Zobrazeno 1 - 10
of 62
pro vyhledávání: '"G J, Offerhaus"'
Autor:
E B, Conemans, G M, Raicu-Ionita, C R C, Pieterman, K M A, Dreijerink, O M, Dekkers, A R, Hermus, W W, de Herder, M L, Drent, A N A, van der Horst-Schrivers, B, Havekes, P H, Bisschop, G J, Offerhaus, I H M, Borel Rinkes, G D, Valk, H Th M, Timmers, M R, Vriens
Publikováno v:
Journal of endocrinological investigation. 41(6)
Pancreatic neuroendocrine tumors are a major manifestation of multiple endocrine neoplasia type 1 (MEN1). This tumor syndrome is caused by germline mutations in MEN1, encoding menin. Insight into pathogenesis of these tumors might lead to new biomark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f046f9dee791fdc0b2ab88014432504c
https://pubmed.ncbi.nlm.nih.gov/29134609
https://pubmed.ncbi.nlm.nih.gov/29134609
Publikováno v:
Familial Cancer. 1:181-185
PARTIIPARTII Molecular andPhenotvvic Studies of Peutz-Jeshers Syndrome Chapte rr 7 Jann Peutz, Harold Jeghers and a remarkable combination of polyposis andd pigmentatio n of the skin and mucous membranes Josbertt J. Keller , G, Johan A, Offerhaus, Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7936376feb31b2dfe597c99279217d
https://doi.org/10.1023/a:1021149327174
https://doi.org/10.1023/a:1021149327174
Autor:
G J Offerhaus, Ralph H. Hruban, Wolter J. Mooi, Robbert J.C. Slebos, Otilia Dalesio, Sjoerd Rodenhuis
Publikováno v:
JNCI: Journal of the National Cancer Institute. 83:1024-1027
To investigate a possible relationship between the exposure to tobacco smoke and the presence of ras point mutations, we examined lung adenocarcinoma samples from 27 smokers and from 27 nonsmokers. Activating point mutations in K-ras (also known as K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabc20b9f8b3487bb8f2f0420e17f2db
https://doi.org/10.1093/jnci/83.14.1024
https://doi.org/10.1093/jnci/83.14.1024
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 148(7)
To provide an embryological explanation for the presence of ovarian stroma in cystadenomas of the liver and pancreas.Investigation of patients and embryos.From 1997 to 2001 in the Academic Medical Centre, Amsterdam, the Netherlands, nine women were t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8f9479afa0649df4f083d7920cf8d9b
https://pubmed.ncbi.nlm.nih.gov/15015250
https://pubmed.ncbi.nlm.nih.gov/15015250
Publikováno v:
Familial cancer. 1(3-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cccc1dbcb83c5dd5fb98de40fe9694aa
https://pubmed.ncbi.nlm.nih.gov/14574176
https://pubmed.ncbi.nlm.nih.gov/14574176
Autor:
J J, Keller, G J, Offerhaus, P, Drillenburg, E, Caspers, A, Musler, A, Ristimäki, F M, Giardiello
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(12)
Sulindac causes the reduction of adenomas in familial adenomatous polyposis (FAP) patients, but complete regression is unusual, and breakthrough of colorectal carcinoma during sulindac treatment has been described. The molecular features related to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25339cff7b8881258b4ead23e0f443c9
https://pubmed.ncbi.nlm.nih.gov/11751493
https://pubmed.ncbi.nlm.nih.gov/11751493
Autor:
A C, Tersmette, G M, Petersen, G J, Offerhaus, F C, Falatko, K A, Brune, M, Goggins, E, Rozenblum, R E, Wilentz, C J, Yeo, J L, Cameron, S E, Kern, R H, Hruban
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)
It has been estimated that familial aggregation and genetic susceptibility play a role in as many as 10% of patients with pancreatic cancer (PC). The quantified prospective risk of PC among first-degree relatives of PC patients has not been investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ed35e826d6d5716abdf5f1706f12fe1
https://pubmed.ncbi.nlm.nih.gov/11297271
https://pubmed.ncbi.nlm.nih.gov/11297271
Autor:
J W, van Sandick, J J, van Lanschot, F J, ten Kate, G J, Offerhaus, P, Fockens, G N, Tytgat, H, Obertop
Publikováno v:
Cancer. 88(11)
As an alternative to surgical resection, endoscopic treatment modalities are being explored for the treatment of patients with early esophageal carcinoma. This study aimed to evaluate patterns of local growth and regional dissemination of early adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c43461bbeddb02f96866fadb901c546
https://pubmed.ncbi.nlm.nih.gov/10861416
https://pubmed.ncbi.nlm.nih.gov/10861416
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
Sebaceous gland carcinomas (SGCs) are rare malignant skin tumors occurring sporadically or as a phenotypic feature of the Muir-Torre syndrome (MTS). A subset of patients with MTS have a variant of the hereditary nonpolyposis colorectal cancer syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54a877ad3369107457d19790e84f955c
https://pubmed.ncbi.nlm.nih.gov/10815898
https://pubmed.ncbi.nlm.nih.gov/10815898
Autor:
R E, Wilentz, M, Goggins, M, Redston, V A, Marcus, N V, Adsay, T A, Sohn, S S, Kadkol, C J, Yeo, M, Choti, M, Zahurak, K, Johnson, M, Tascilar, G J, Offerhaus, R H, Hruban, S E, Kern
Publikováno v:
The American journal of pathology. 156(5)
Medullary carcinomas of the pancreas are a recently described, histologically distinct subset of poorly differentiated adenocarcinomas that may have a unique pathogenesis and clinical course. To further evaluate these neoplasms, we studied genetic, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b7deda91c8cb2c2f5a63dcbe0c45069
https://pubmed.ncbi.nlm.nih.gov/10793075
https://pubmed.ncbi.nlm.nih.gov/10793075