Zobrazeno 1 - 10
of 48
pro vyhledávání: '"G J, Kaczorowski"'
Autor:
G J, Kaczorowski, M L, Garcia
Publikováno v:
International review of neurobiology. 128
High conductance, calcium-activated potassium (BK) channels (KCa1.1) are important in regulating physiologic responses in many types of tissues and, as such, present opportunities for development of new therapeutic agents. Both channel agonists and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55c9ebdc4cfa875ab721b0f4299eb48e
https://pubmed.ncbi.nlm.nih.gov/27238271
https://pubmed.ncbi.nlm.nih.gov/27238271
Autor:
M L Garcia, G J Kaczorowski
High conductance, calcium-activated potassium (BK) channels (KCa1.1) are important in regulating physiologic responses in many types of tissues and, as such, present opportunities for development of new therapeutic agents. Both channel agonists and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15078173a0d6445a7b2e633e95e07ef4
https://doi.org/10.1016/bs.irn.2016.02.013
https://doi.org/10.1016/bs.irn.2016.02.013
Publikováno v:
Journal of Applied Physiology. 74:1879-1884
Airway smooth muscle plasma membranes contain a variety of functional K+ channels. In particular, there is a predominance of Ca(2+)-activated K+ channels (maxi-K). Inhibition of these K+ channels has been postulated to account for the ability of char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397196ad69e58e3a2e01cfc07e943b15
https://doi.org/10.1152/jappl.1993.74.4.1879
https://doi.org/10.1152/jappl.1993.74.4.1879
Publikováno v:
British journal of pharmacology. 131(4)
Correolide (1 - 10 microM), a nortriterpene purified from Spachea correae and a selective blocker of Kv1 potassium channels, elicits repetitive twitching in guinea-pig ileum. This effect is not seen in guinea-pig duodenum, portal vein, urinary bladde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5616759476ed629d9914aa9da32581bc
https://pubmed.ncbi.nlm.nih.gov/11030727
https://pubmed.ncbi.nlm.nih.gov/11030727
Autor:
M, Hanner, W A, Schmalhofer, B, Green, C, Bordallo, J, Liu, R S, Slaughter, G J, Kaczorowski, M L, Garcia
Publikováno v:
The Journal of biological chemistry. 274(36)
Correolide, a novel nortriterpene natural product, potently inhibits the voltage-gated potassium channel, K(v)1.3, and [(3)H]dihydrocorreolide (diTC) binds with high affinity (K(d) approximately 10 nM) to membranes from Chinese hamster ovary cells th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac0b1f18c1a37a14ab4a90dc06c2bea9
https://pubmed.ncbi.nlm.nih.gov/10464244
https://pubmed.ncbi.nlm.nih.gov/10464244
Autor:
M L, Garcia, K M, Giangiacomo, M, Hanner, H G, Knaus, O B, McManus, W A, Schmalhofer, G J, Kaczorowski
Publikováno v:
Methods in enzymology. 294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d83b8f4008573fffbe305f7b6c9ecfe3
https://pubmed.ncbi.nlm.nih.gov/9916233
https://pubmed.ncbi.nlm.nih.gov/9916233
Publikováno v:
Methods in enzymology. 294
The search for peptidyl inhibitors of K+ channels is a very active area of investigation. In addition to scorpion venoms, other venom sources have been investigated; all of these sources have yielded novel peptides with interesting properties. For in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77dffd028976a0d25a2197ec9f0790a2
https://pubmed.ncbi.nlm.nih.gov/9916251
https://pubmed.ncbi.nlm.nih.gov/9916251
Autor:
M, Hanner, R, Vianna-Jorge, A, Kamassah, W A, Schmalhofer, H G, Knaus, G J, Kaczorowski, M L, Garcia
Publikováno v:
The Journal of biological chemistry. 273(26)
Coexpression of alpha and beta subunits of the high conductance Ca2+-activated K+ (maxi-K) channel leads to a 50-fold increase in the affinity for 125I-charybdotoxin (125I-ChTX) as compared with when the alpha subunit is expressed alone (Hanner, M.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::468b3575f0fb0824c72665244cceddab
https://pubmed.ncbi.nlm.nih.gov/9632689
https://pubmed.ncbi.nlm.nih.gov/9632689
Autor:
R O, Koch, S G, Wanner, A, Koschak, M, Hanner, C, Schwarzer, G J, Kaczorowski, R S, Slaughter, M L, Garcia, H G, Knaus
Publikováno v:
The Journal of biological chemistry. 272(44)
Neurons require specific patterns of K+ channel subunit expression as well as the precise coassembly of channel subunits into heterotetrameric structures for proper integration and transmission of electrical signals. In vivo subunit coassembly was in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae10a98db5e15019dd155585d623de89
https://pubmed.ncbi.nlm.nih.gov/9346893
https://pubmed.ncbi.nlm.nih.gov/9346893
Autor:
M L, Garcia, M, Hanner, H G, Knaus, R, Koch, W, Schmalhofer, R S, Slaughter, G J, Kaczorowski
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27fcc4ce2a703fcd61291b0abc9eb3eb
https://pubmed.ncbi.nlm.nih.gov/9160122
https://pubmed.ncbi.nlm.nih.gov/9160122