Zobrazeno 1 - 10
of 277
pro vyhledávání: '"G J, Dougherty"'
Autor:
Shona T. Dougherty, Gregory M. Hayes, Julie F. Dirks, Carmine Carpenito, Peter D Davis, G J Dougherty
Publikováno v:
Cancer Gene Therapy. 9:133-141
In order to determine the potential of alternative splicing as a means of targeting the expression of therapeutic genes to tumor cells in vivo, a series of episomal plasmid-based "splice-activated gene expression" (pSAGE) vectors was generated, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e2fa16f165d97a8b53e1033d729338
https://doi.org/10.1038/sj.cgt.7700427
https://doi.org/10.1038/sj.cgt.7700427
Autor:
Roland K. Chiu, G J Dougherty, Shona T. Dougherty, Armin Droll, Carmine Carpenito, David L. Cooper
Publikováno v:
Experimental Cell Research, 248(1), 314-21. HANLEY & BELFUS-ELSEVIER INC
Correlations have been noted between the expression of certain alternatively spliced CD44 isoforms and the metastatic propensity of various histologically distinct tumor cell types. The precise mechanism by which particular CD44 isoforms contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf85f4c4140da946e62d7157351a0cf
https://doi.org/10.1006/excr.1999.4391
https://doi.org/10.1006/excr.1999.4391
Publikováno v:
Experimental Cell Research. 234:225-232
Some cell lines grown for only two cell doublings as multicell spheroids develop a form of resistance to killing by ionizing radiation that has been called the “contact” effect. While our previous results have implicated a role for higher order c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddd8e105935ae49ba05c326dc1c7ea9
https://doi.org/10.1006/excr.1997.3613
https://doi.org/10.1006/excr.1997.3613
Publikováno v:
The Journal of Immunology. 159:919-925
Phagocytosis of apoptotic neutrophil granulocytes by macrophages at inflammatory sites is an important determinant of the process by which inflammation resolves. We demonstrate that phagocytosis of apoptotic neutrophils, but not apoptotic lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0cd72888854fee81cfc3ab6e4d3ef7
https://doi.org/10.4049/jimmunol.159.2.919
https://doi.org/10.4049/jimmunol.159.2.919
Publikováno v:
Cancer Immunology, Immunotherapy. 44:165-172
In order to better define the role played by tumor-cell-derived macrophage-colony-stimulating factor (M-CSF) in regulating the recruitment and phenotype of tumor-associated macrophages, Polyoma large T-transformed fibroblastoid cell lines, derived fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c167cd40bb88bb52779202c15ea5ba3e
https://doi.org/10.1007/s002620050369
https://doi.org/10.1007/s002620050369
Publikováno v:
British Journal of Haematology. 97:22-28
We have identified three non-cross-reacting anti-human CD44 monoclonal antibodies that have significant positive or negative (or no) effects on normal human haemopoiesis in the long-term culture (LTC) system. These effects manifested as increases or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87a2e578ff238e71a92a0376c5da3ae
https://doi.org/10.1046/j.1365-2141.1997.d01-2139.x
https://doi.org/10.1046/j.1365-2141.1997.d01-2139.x
Publikováno v:
Cancer Letters. 111:27-37
The molecular mechanisms that regulate the production and/or functional activity of intratumoral tumor necrosis factor-alpha (TNF-alpha) remain poorly defined. To begin to address this issue we have examined the level of TNF-alpha mRNA and protein pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120b623056a729e18a584b169d194cee
https://doi.org/10.1016/s0304-3835(96)04490-4
https://doi.org/10.1016/s0304-3835(96)04490-4
Publikováno v:
Blood. 86:2976-2985
CD44 is a widely expressed, multifunctional, cell-surface glycoprotein that has been implicated in the regulation of normal hematopoiesis. In addition, expression of particular isoforms of CD44 has been associated with malignant transformation and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bf034ef8a7d0f324f48af76431e7a08
https://doi.org/10.1182/blood.v86.8.2976.2976
https://doi.org/10.1182/blood.v86.8.2976.2976
Publikováno v:
Trends in Glycoscience and Glycotechnology. 7:45-56
CD44は生体内に広範に分布する細胞表面糖タンパク質で、リンパ造血、骨髄造血、リンパ球再循環、がん転移、単球やマクロファージの活性化など、接着に依存した多くの細胞現象に重要
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab1c209490b2a2621792f91120f56ed
https://doi.org/10.4052/tigg.7.45
https://doi.org/10.4052/tigg.7.45
Publikováno v:
British Journal of Cancer
Cellular populations in the squamous cell carcinoma SCCVII, growing in C3H/HeN mice given Photofrin, were examined at various time intervals during the photodynamic light treatment and up to 8 h later. Cell populations present within excised tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa6a0fa49aea251e45030bfaeed0f04
http://europepmc.org/articles/PMC2033617
http://europepmc.org/articles/PMC2033617