Zobrazeno 1 - 10
of 10
pro vyhledávání: '"G J, Christianson"'
Autor:
G J Christianson, W Brooks, S Vekasi, E A Manolfi, J Niles, S L Roopenian, J B Roths, R Rothlein, D C Roopenian
Publikováno v:
The Journal of Immunology. 159:4781-4792
The goal of this study was to determine whether class I proteins play an important role in the regulation of Ig and to elucidate the mechanism(s) involved. We analyzed the phenotype imposed by a null allele of beta 2-microglobulin (beta 2m). Serum Ig
Autor:
D. V. Serreze, W. S. Gallichan, D. P. Snider, K. Croitoru, K. L. Rosenthal, E. H. Leiter, G. J. Christianson, M. E. Dudley, D. C. Roopenian
Publikováno v:
Diabetes. 45:902-908
Autor:
G J Christianson, R L Blankenburg, T M Duffy, D Panka, J B Roths, A Marshak-Rothstein, D C Roopenian
Publikováno v:
The Journal of Immunology. 156:4932-4939
MRL-lpr/lpr mice develop a distinctive immunologic disease characterized by accumulation of unusually large numbers of T cells in the peripheral lymphoid organs. Most of the accumulating T cells express an alpha beta-TCR but are peculiar in that they
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(8)
Of the many minor histocompatibility (H) Ags that have been detected in mice, the ability to induce graft vs host disease (GVHD) after bone marrow transplantation is restricted to a limited number of immunodominant Ags. One such murine Ag, B6dom1, is
Autor:
A, Boesteanu, M, Brehm, L M, Mylin, G J, Christianson, S S, Tevethia, D C, Roopenian, S, Joyce
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
CD8+ T cells respond to Ags when their clonotypic receptor, the TCR, recognizes nonself peptides displayed by MHC class I molecules. The TCR/ligand interactions are degenerate because, in its life time, the TCR interacts with self MHC class I-self pe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(2)
The H3 complex, on mouse Chromosome 2, is an important model locus for understanding mechanisms underlying non-self Ag recognition during tissue transplantation rejection between MHC-matched mouse strains. H3a is a minor histocompatibility Ag gene, l
Autor:
G J, Christianson, W, Brooks, S, Vekasi, E A, Manolfi, J, Niles, S L, Roopenian, J B, Roths, R, Rothlein, D C, Roopenian
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(10)
The goal of this study was to determine whether class I proteins play an important role in the regulation of Ig and to elucidate the mechanism(s) involved. We analyzed the phenotype imposed by a null allele of beta 2-microglobulin (beta 2m). Serum Ig
Autor:
G J, Christianson, R L, Blankenburg, T M, Duffy, D, Panka, J B, Roths, A, Marshak-Rothstein, D C, Roopenian
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(12)
MRL-lpr/lpr mice develop a distinctive immunologic disease characterized by accumulation of unusually large numbers of T cells in the peripheral lymphoid organs. Most of the accumulating T cells express an alpha beta-TCR but are peculiar in that they
Autor:
B R, Blazar, D C, Roopenian, P A, Taylor, G J, Christianson, A, Panoskaltsis-Mortari, D A, Vallera
Publikováno v:
Transplantation. 61(4)
To determine whether a disparity at a single miH genetic loci are sufficient to generate GVHD in mice, we focused on well-known genetic alleleic differences at the miH gene loci, H3 and H4. For H3 congenic GVHD studies, C57BL/10 (H2b) mice were used
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(9)
This work addresses the functional basis of classical minor histocompatibility (H) loci. We focus on the H-3 locus, which is actually a complex genetic unit to which the phenotypic trait of tissue rejection, genes whose products stimulate specific su