Zobrazeno 1 - 10
of 347
pro vyhledávání: '"G Illei"'
Autor:
Dominic Sinibaldi, Gabor G Illei, Wendy I White, S Sam Lim, Jason Cobb, Ahmad Akhgar, Lingmin Zeng, Alton B Farris, Monica Battle, David Chain, Jennifer A Cann
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss 1 (2023)
Objective Lupus nephritis (LN) is diagnosed by biopsy, but longitudinal monitoring assessment methods are needed. Here, in this preliminary and hypothesis-generating study, we evaluate the potential for using urine proteomics as a non-invasive method
Externí odkaz:
https://doaj.org/article/96a750e6e45844798878b7804593e4aa
Autor:
Junjun Luan, Jingqi Fu, Chengjie Chen, Congcong Jiao, Weiwei Kong, Yixiao Zhang, Qing Chang, Yanqiu Wang, Detian Li, Gabor G. Illei, Jeffrey B. Kopp, Jingbo Pi, Hua Zhou
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background The prevalence of lupus nephritis (LN) remains high despite various emerging monoclonal antibodies against with targeting systemic lupus erythematosus (SLE). Renal fibrosis is the main feature of late stage LN, and novel therapeut
Externí odkaz:
https://doaj.org/article/a82964f9cea44bbbad5b57b1bfa2f11c
Autor:
Junjun Luan, Congcong Jiao, Cong Ma, Yixiao Zhang, Xiangnan Hao, Guangyu Zhou, Jingqi Fu, Xingyu Qiu, Hongyu Li, Wei Yang, Gabor G. Illei, Jeffrey B. Kopp, Jingbo Pi, Hua Zhou
Publikováno v:
Oxidative medicine and cellular longevity. 2022
Recent studies have focused on nuclear-encoded circular RNAs (circRNAs) in kidney diseases, but little is known about mitochondrial circRNAs. Differentially expressed circRNAs were analyzed by RNA deep sequencing from lupus nephritis (LN) biopsies an
Autor:
Ahmad Akhgar, Dominic Sinibaldi, Lingmin Zeng, Alton B Farris, Jason Cobb, Monica Battle, David Chain, Jennifer A Cann, Gábor G Illei, S Sam Lim, Wendy I White
Publikováno v:
Lupus Science & Medicine. 10:e000747
ObjectiveLupus nephritis (LN) is diagnosed by biopsy, but longitudinal monitoring assessment methods are needed. Here, in this preliminary and hypothesis-generating study, we evaluate the potential for using urine proteomics as a non-invasive method
Autor:
Sencer Goklemez, Sarfaraz Hasni, Frances T Hakim, Paolo A Muraro, Filip Pirsl, Jeremy Rose, Sarfraz Memon, Daniel F Fowler, Seth M Steinberg, Eva H Baker, Sandya R Panch, Ronald Gress, Gabor G Illei, Peter E Lipsky, Steven Z Pavletic
Publikováno v:
Rheumatology (Oxford)
Objective Autologous haematopoietic cell transplantation (AHSCT) improves immunologic dysfunction in patients with SLE. However, the curative potential of this therapy remains uncertain. This study reports outcomes in SLE patients receiving a lymphod
Autor:
Jodi L. Karnell, Michael A Smith, William Rees, Victoria P. Werth, Jill Henault, Li Yan, Katherine Ann Vousden, Jeffrey M. Riggs, Miguel A. Sanjuan, Vib Trial Investigators, G. Illei, John N. Ratchford, Yanping Wu, Simone M. Nicholson, Kerry A. Casey, Nanette Mittereder, Michele Gunsior, Jorn Drappa
Publikováno v:
Science translational medicine. 13(595)
Plasmacytoid dendritic cells (pDCs) not only are specialized in their capacity to secrete large amounts of type I interferon (IFN) but also serve to enable both innate and adaptive immune responses through expression of additional proinflammatory cyt
Autor:
Dominic Sinibaldi, Nehal N. Mehta, G. Illei, Mariana J. Kaplan, Binbing Yu, Xinghao Wang, Philip M. Carlucci, L. Wang, Kerry A. Casey, Martin P. Playford, Shiliang Wang, Wendy I. White, Nickie L Seto, Michael A Smith, Alan T. Remaley
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)References. 73(3)
OBJECTIVE Neutrophil dysregulation and the type I interferon (IFN) axis have been proposed to contribute to premature cardiovascular disease, a leading cause of mortality in patients with systemic lupus erythematosus (SLE). In the present study, we e
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e30679 (2012)
There is an increasing interest in using microRNAs (miRNA) as biomarkers in autoimmune diseases. They are easily accessible in many body fluids but it is controversial if they are circulating freely or are encapsulated in microvesicles, particularly
Externí odkaz:
https://doaj.org/article/9e81d38d15fd40e09f958eb3e23c4614
Publikováno v:
Lupus. 27:955-962
A post-hoc analysis of pooled data from two Phase IIb trials (sifalimumab; NCT01283139, anifrolumab; NCT01438489) assessed the clinical significance of a Systemic Lupus Erythematosus (SLE) Responder Index (SRI(4)) response (Week 52) for 736 patients
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19962 (2011)
Intercellular adhesion molecule-1 (ICAM-1) is involved in migration and co-stimulation of T and B cells. Membrane bound ICAM-1 is over expressed in the salivary glands (SG) of Sjögren's syndrome (SS) patients and has therefore been proposed as a pot
Externí odkaz:
https://doaj.org/article/e7e94273db88427781e2ce01653f7fed