Zobrazeno 1 - 10
of 27
pro vyhledávání: '"G Ia, Dubur"'
Autor:
E V, Ivanov, T V, Ponomareva, G N, Merkushev, I K, Romanovich, G Ia, Dubur, E A, Bisenieks, Ia R, Uldrikis, Ia Ia, Poĭkans
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 44(5)
First attempt to analyse radiation modifying action of 52 compounds--derivatives of 1,4-dihydropyridine is presented. Many of these compounds have electrodonating and antioxidative activities. Local radioprotective effects of the substances has been
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (1)
The paper summarizes the results of studies into the modifying effect of some 1,4-dihydroisonicotinic acid (1,4-DHINA) derivatives during chemical mutagenesis in eukaryotic organisms. The compounds under study are effective in reducing the incidence
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 116(10)
The experiments on focal penicillin-induced epileptic activity in the brain cortex (Wistar rats) and bicuculline- and thiosemicarbazide-induced seizures (Icr:Icl mice) showed that the glutapyrone possessed a significant antiepileptic activity. As pre
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 114(7)
In experiments on awake cats before and after intracerebral hemorrhage influence of cerebrocrast and nimodipine intravenous infusion (1 microgram/kg-1/min-1 during 60 min) on cerebral blood flow (CBF) in the cortex, thalamus and reticular formation a
Autor:
A G, Pokrovskiĭ, O A, Pliasunova, L S, Sandakhchiev, O I, Kiselev, O N, Chupakhin, V N, Charushin, M G, Ponizovskiĭ, G Ia, Dubur, E A, Bisenieks
Publikováno v:
Doklady Akademii nauk. 326(2)
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 112(10)
In experiments on freely moving male Wistar rats it was shown that IOS-1.1212 (1,4-dihydropyridine) in a dose 2 and 10 mg/kg (i. p.) suppressed the penicillin-induced focal epileptic activity in cerebral cortex. Similar suppressing effect of IOS-1.12
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 110(12)
It was found therapeutic-preventive effectiveness of antioxidants (1,4-dihydropyridine derivatives) at poisoning with malathion insecticide. The effect of 1,4-dihydropyridine derivatives can be attributed to a prevention of lipid peroxidation. Antiox
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 110(10)
Cardiovascular drugs nifedipine and riodipine (1,4-dihydropyridine derivatives) were studied as to their effect on some biochemical characteristics of erythrocytes. Both compounds failed to effect 2,3-diphosphoglycerate concentration in intact erythr
Publikováno v:
Tsitologiia. 23(8)
A fluorescent compound 4-(p-dimethylinostyryl)-1-methylpyridinium (DSM) has been synthesized, having the absorption maximum about 450 nm and the fluorescence maximum about 590 nm in a water solution. A considerable increase of its fluorescence intens
Publikováno v:
Voprosy meditsinskoi khimii. 22(5)
Effect of antioxidants on the rate of free radical peroxidation was studied in mitochondria in presence of Fe2+. For this purpose derivatives of 1,4-dihydroxypyridine, their heteroaromatic analogues, NAD-H+ and butyl hydroxytoluene (35 substances) we