Zobrazeno 1 - 10
of 23
pro vyhledávání: '"G I Murray"'
Autor:
W L, Allen, P D, Dunne, S, McDade, E, Scanlon, M, Loughrey, H, Coleman, C, McCann, K, McLaughlin, Z, Nemeth, N, Syed, P, Jithesh, K, Arthur, R, Wilson, V, Coyle, D, McArt, G I, Murray, L, Samuel, P, Nuciforo, J, Jimenez, G, Argiles, R, Dienstmann, J, Tabernero, L, Messerini, S, Nobili, E, Mini, K, Sheahan, E, Ryan, P G, Johnston, S, Van Schaeybroeck, M, Lawler, D B, Longley
Transcriptomic profiling of colorectal cancer (CRC) has led to identification of four consensus molecular subtypes (CMS1-4), which have prognostic value in stage II/III disease. More recently, the Colorectal Cancer Intrinsic Subtypes (CRIS) classific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9141b5bd3c825b310e2851e50702c8ff
https://europepmc.org/articles/PMC6040635/
https://europepmc.org/articles/PMC6040635/
Publikováno v:
Xenobiotica. 28:443-456
1. Glutathione S-transferase (GST) activity in the cytosol of renal cortex and tumours from eight men and eight women was measured using 1-chloro-2,4-dinitrobenzene (CDNB) as a substrate. GST activities ranged from 685 to 2192 nmol/min/mg protein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee30300370c4f4ff7969fcc7d68b3e3
https://doi.org/10.1080/004982598239371
https://doi.org/10.1080/004982598239371
Autor:
K, Cuschieri, D H, Brewster, C, Graham, S, Nicoll, A R W, Williams, G I, Murray, D, Millan, I, Johannessen, A, Hardie, H A, Cubie
Publikováno v:
International journal of cancer. 135(11)
While much is known about the influence of HPV type on the progression of pre-invasive cervical lesions, the impact of HPV type on cervical cancer prognosis is less evidenced. Thus, we assessed the impact of HPV type on the survival of women diagnose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acc58596ca60b42f69cae76a9ef0ff51
https://pubmed.ncbi.nlm.nih.gov/24740764
https://pubmed.ncbi.nlm.nih.gov/24740764
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 24(2)
Nerve fibers can exert trophic/anti-trophic effects on epithelial cells. Substance P (SP) is a pro-proliferative neuropeptide, whereas sympathetic noradrenaline is anti-proliferative at high concentrations.Density of noradrenergic and sensory nerve f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dec49ce802e6d8df0343ee0ffd82b3f
https://pubmed.ncbi.nlm.nih.gov/22093159
https://pubmed.ncbi.nlm.nih.gov/22093159
Publikováno v:
Biochemical pharmacology. 62(2)
The overexpression of human cytochrome P450 CYP1B1 has been observed in a wide variety of malignant tumours, but the protein is undetectable in normal tissues. A number of cytochrome P450 enzymes are known to metabolise a variety of anticancer drugs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bc2ec9a8f50ea6a4cfec30f4f4a3a56
https://pubmed.ncbi.nlm.nih.gov/11389879
https://pubmed.ncbi.nlm.nih.gov/11389879
Autor:
S C, Pritchard, M C, Nicolson, C, Lloret, J A, McKay, V G, Ross, K M, Kerr, G I, Murray, H L, McLeod
Publikováno v:
Oncology reports. 8(2)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide, with a very poor survival rate. Therefore there is intense scrutiny to provide a better understanding of the molecular and cellular processes involved in this aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ab235c1215dad3516bec3d655b44f89
https://pubmed.ncbi.nlm.nih.gov/11182067
https://pubmed.ncbi.nlm.nih.gov/11182067
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
The cytochrome P450 1B1 (CYP1B1) is involved in the metabolism of procarcinogens and xenobiotics. Human CYP1B1 protein has been detected in a variety of tumors but is not detected in adjacent normal tissues or in liver. This suggests that CYP1B1 coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51200c7bc003f7d4b1f3d3d7cb3eb03c
https://pubmed.ncbi.nlm.nih.gov/11160641
https://pubmed.ncbi.nlm.nih.gov/11160641
Autor:
G I, Murray
Publikováno v:
The Journal of pathology. 192(4)
The cytochromes P450 (P450) are a large group of constitutive and inducible haem-containing enzymes, which have a central role in the oxidative metabolism of a diverse range of xenobiotics. Many P450 substrates are carcinogenic, while other substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97754635088671ed941cc3297e183421
https://pubmed.ncbi.nlm.nih.gov/11113857
https://pubmed.ncbi.nlm.nih.gov/11113857
Autor:
R G, Jaffrey, S C, Pritchard, C, Clark, G I, Murray, J, Cassidy, K M, Kerr, M C, Nicolson, H L, McLeod
Publikováno v:
Cancer research. 60(16)
Genomic instability is observed in the majority of human tumors. Dysregulation of the mitotic spindle checkpoint is thought to be one of the mechanisms that facilitate aneuploidy in tumor cells. Mutations in the mitotic spindle checkpoint kinase BLUB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b28671c3cec7790a5a60b69bb04d8655
https://pubmed.ncbi.nlm.nih.gov/10969775
https://pubmed.ncbi.nlm.nih.gov/10969775
Publikováno v:
International journal of cancer. 88(1)
Cyclin D1 is a key cell cycle regulatory protein, the expression and subcellular localization of which is often altered in human tumor cells. A common A/G single nucleotide polymorphism (A870G) in exon 4 of the cyclin D1 gene, CCND1, is associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8a13a4aabeebca1ababf0fc310d6994
https://pubmed.ncbi.nlm.nih.gov/10964085
https://pubmed.ncbi.nlm.nih.gov/10964085