Prevalence of and Risk Factors for Hepatic Steatosis and Nonalcoholic Fatty Liver Disease in People With Type 2 Diabetes:the Edinburgh Type 2 Diabetes Study

Autor: Rachel M. Williamson, G I Johnston, Lisa D. Nee, Elisa Perry, Peter C. Hayes, Jackie F. Price, Liesbeth A.F. Van Look, S Glancy, Rebecca M. Reynolds, Mark W. J. Strachan, Brian M. Frier

Publikováno v: Williamson, R M, Price, J F, Glancy, S, Perry, E, Nee, L D, Hayes, P C, Frier, B M, Van Look, L A F, Johnston, G I & Reynolds, R M & Strachan, M 2011, ' Prevalence of and Risk Factors for Hepatic Steatosis and Nonalcoholic Fatty Liver Disease in People With Type 2 Diabetes : the Edinburgh Type 2 Diabetes Study ', Diabetes Care, vol. 34, no. 5, pp. 1139-1144 . https://doi.org/10.2337/dc10-2229
Diabetes Care

OBJECTIVE Type 2 diabetes is an established risk factor for development of hepatic steatosis and nonalcoholic fatty liver disease (NAFLD). We aimed to determine the prevalence and clinical correlates of these conditions in a large cohort of people wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af7eb20528e7be8eec3fd0f025eb226
https://hdl.handle.net/20.500.11820/84d1cb62-6d8b-45a2-b497-edeceaf91a2f

Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1

Autor: Michael A. Gimbrone, Jong Il Kim, R Eddy, G I Johnston, T Shows, Tucker Collins, Amy J. Williams, Michael P. Bevilacqua

Publikováno v: Journal of Biological Chemistry. 266:2466-2473

Endothelial-leukocyte adhesion molecule 1 is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. Endothelial-leukocyte adhesion molecule 1 is a member of the selectin family of cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f44ef45db634e9dd4dae036ae31779e
https://doi.org/10.1016/s0021-9258(18)52267-5

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal

Autor: Joshua M. Brickman, Andrea L. Zamparini, G I Johnston, Tim M Watts, Clare Gardner, Simon R. Tomlinson

Publikováno v: Zamparini, A L, Watts, T, Gardner, C E, Tomlinson, S R, Johnston, G I & Brickman, J M 2006, ' Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal ', Development, vol. 133, no. 18, pp. 3709-22 . https://doi.org/10.1242/dev.02516

In Xenopus , the establishment of the anteroposterior axis involves two key signalling pathways, canonical Wnt and Nodal-related TGFβ. There are also a number of transcription factors that feedback upon these pathways. The homeodomain protein Hex, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9f09b40ba8ff5b4554dfe2e7badeb2
https://hdl.handle.net/20.500.11820/cbce62f2-beb7-469b-87d6-f943e3c9429e

Structure of the human gene encoding granule membrane protein-140, a member of the selectin family of adhesion receptors for leukocytes

Autor: G I, Johnston, G A, Bliss, P J, Newman, R P, McEver

Publikováno v: The Journal of biological chemistry. 265(34)

GMP-140, an inducible granule membrane protein of platelets and endothelial cells, is a member of the selectin family of cell surface receptors that mediate interactions of leukocytes with the blood vessel wall. These molecules all contain an N-termi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ef87965020327a1b49edd14a84dab34
https://pubmed.ncbi.nlm.nih.gov/1701178

EXTRACELLULAR CALCIUM AND PLATELET GLYCOPROTEINS

Autor: G I Johnston, I Jabbal-Gill, S Heptinstall

Publikováno v: XIth International Congress on Thrombosis and Haemostasis.

Platelet membrane glycoproteins lib and Ilia form Ca++-dependent heterodimer complexes that contain binding sites for fibrinogen and therefore are relevant to the ability of platelets to aggregate together. In this study we investigated the effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9915056db2a21a6a6523eab1874a36da
https://doi.org/10.1055/s-0038-1643507