Zobrazeno 1 - 10
of 43
pro vyhledávání: '"G Hoste"'
Autor:
Ines Nevelsteen, Ann Smeets, Chantal Van Ongeval, Hans Wildiers, Anne-Sophie Van Rompuy, Laurence Slembrouck, Caroline Weltens, G Hoste, Els Van Nieuwenhuysen, Giuseppe Floris, Isabelle Vanden Bempt, Kevin Punie, Patrick Neven, Lynn Jongen, Sileny Han
Publikováno v:
Modern Pathology. 34:1297-1309
Multigene signatures (MGS) are used to guide adjuvant chemotherapy (aCT) decisions in patients diagnosed with estrogen receptor (ER)-positive HER2-negative early breast cancer. We used results from three MGS (Oncotype DX® (ODX), MammaPrint® (MP) or
Autor:
Sileny Han, Erik Van Limbergen, Ines Nevelsteen, Ann Smeets, Lynn Jongen, Hans Wildiers, Isabelle Vanden Bempt, Giuseppe Floris, Philippe Moerman, Laurence Slembrouck, Patrick Neven, Kevin Punie, Caroline Weltens, G Hoste, Els Van Nieuwenhuysen
Publikováno v:
Cancer Research. 80:P3-07
Background Multigene signatures (MGS) select women with estrogen receptor positive human epidermal growth factor receptor 2 negative (ER+/HER2-) breast cancers where adjuvant chemotherapy (aCT) can be avoided. However, MGS are expensive and not alway
Autor:
Hans Wildiers, Cécile Reyes, Sileny Han, Lorenza Mittempergher, Timothé Cynober, F Reyal, Leonie J. M. J. Delahaye, Kevin Punie, Liesbet Vliegen, Ines Nevelsteen, Enora Laas Faron, Laurence Slembrouck, Petra Sintubin, Sara Vander Borght, G Hoste, Patrick Neven, Giuseppe Floris, Audrey Rapinat, Ann Smeets, Sylvain Baulande, Lynn Jongen, Mylène Bohec, Virginie Raynal, David Gentien, Céline Helsmoortel, Mireille Snel, Els Van Nieuwenhuysen, Lauren Darrigues, Isabelle Vanden Bempt, Anke T. Witteveen, Sari Neijenhuis, Cecile Laurent, Annuska M. Glas, Anne Vincent Salomon
Publikováno v:
Translational Oncology, Vol 12, Iss 12, Pp 1557-1565 (2019)
Translational Oncology
Translational Oncology
A previously developed and centrally validated MammaPrint® (MP) and BluePrint® (BP) targeted RNA next-generation sequencing (NGS) kit was implemented and validated in two large academic European hospitals. Additionally, breast cancer molecular subt
Autor:
Machteld Keupers, Chantal Van Ongeval, Eric Legius, Hilde Brems, Patrick Neven, Ellen Denayer, Hilde Van Esch, Renate Prevos, Christine Desmedt, G Hoste, Ines Nevelsteen, Jan Ardui, H. Wildiers, Hilde Peeters, A Smeets, K Punie, Griet Van Buggenhout, Giuseppe Floris, Geneviève Michils
Publikováno v:
Cancer Research. 80:P6-08
Background: The introduction of multi-gene panel testing and improved awareness under patients and physicians has led to an increase of individuals with known germline pathogenic variants in hereditary breast and ovarian cancer (HBOC) genes. Signific
Autor:
Leonie J. M. J. Delahaye, Liesbet Vliegen, P Sintubin, Laurence Slembrouck, E Van Nieuwenhuysen, I. Vanden Bempt, C Helsmoortel, L Darrigues, S Vander Borght, EL Faron, Cécile Reyes, Sileny Han, H. Wildiers, Lynn Jongen, G Hoste, Annuska M. Glas, Patrick Neven, S Neijenhuis, V Raynal, L. Mittempergher, Anne Vincent Salomon, A Smeets, K Punie, Guiseppe Floris, Anke T. Witteveen, Mylène Bohec, Timothé Cynober, F Reyal, Ines Nevelsteen, Audrey Rapinat, Cécile Laurent
Publikováno v:
Cancer Research. 79:P4-08
Background Many countries restrict patient material exchange to central diagnostic laboratories abroad, limiting access to assays like MammaPrint® (MP) and BluePrint® (BP). Both assays are microarray-based, with MP being prognostic for distant recu
Autor:
Patrick Neven, Eric Legius, G Van Buggenhout, Guiseppe Floris, Sileny Han, Caroline Weltens, P D'Hoore, Patrick Berteloot, K Punie, A Smeets, E Van Nieuwenhuysen, H. Wildiers, Hilde Janssen, G Hoste, E. Van Limbergen, Ines Nevelsteen
Publikováno v:
Cancer Research. 79:P5-09
Background The introduction of multi-gene panel testing in the diagnosis of hereditary breast and ovarian cancer (HBOC) has led to an important increase in the detection of breast cancer predisposition genes other than BRCA1 and BRCA2. Methods All in
Publikováno v:
Obstetrics and Gynecology International, Vol 2013 (2013)
Traditional population-based cervical screening programs, based on cytology, have successfully reduced the burden of cervical cancer. Nevertheless limitations remain and new screening methods are emerging. Despite vaccination against the 2 most oncog
Externí odkaz:
https://doaj.org/article/9c38a00dd35f45979732627c6faf952d
Autor:
Laurence Slembrouck, G Hoste, Johan Menten, Hans Wildiers, Carlos L. Arteaga, Isabelle Vanden Bempt, Giuseppe Floris, Kevin Punie, Tom Matton, Lynn Jongen, Sara Vander Borght, Patrick Neven
Publikováno v:
Clinical Drug Investigation. 38:1071-1075
We present the case of a postmenopausal patient with a secondary metastatic ER-positive, HER2-negative breast cancer who was successfully treated with fulvestrant and alpelisib following six lines of therapy. The tumour showed two uncommon PIK3CA mut
Autor:
Benoit Beuselinck, I. Lefever, Nicole Concin, Ignace Vergote, Hans Wildiers, G Hoste, Patrick Berteloot, E Van Nieuwenhuysen, R Salihi, Sileny Han, Patrick Neven, Kevin Punie
Publikováno v:
Breast Cancer Research and Treatment. 171:131-141
We aimed to investigate the role of palbociclib, a first-in-class cyclin-dependent kinase 4 and 6 inhibitor, in postmenopausal women with highly pretreated endocrine therapy-resistant metastatic breast cancer (MBC). Between 28 September 2015 and 14 M
Juvenile papillomatosis of the breast, also known as Swiss cheese disease, is a rare and benign proliferative disorder affecting young women. These patients tend to have a strong family history of cancer. The lesion typically presents as a localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e5c48d00778112fada72ae06a6db3d
https://europepmc.org/articles/PMC6456279/
https://europepmc.org/articles/PMC6456279/