Zobrazeno 1 - 10
of 381
pro vyhledávání: '"G Haydon"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Neuronal activity undergoes significant changes during vigilance states, accompanied by an accommodation of energy demands. While the astrocyte-neuron lactate shuttle has shown that lactate is the primary energy substrate for sustaining neur
Externí odkaz:
https://doaj.org/article/60dff80641184a76b1e5174ab88bd923
Publikováno v:
Genealogy, Vol 7, Iss 1, p 13 (2023)
Identity development among late adolescent university students and its relationship to family history knowledge was examined in this study. Identity development was examined using Marcia’s individual developmental framework (1988) of exploration an
Externí odkaz:
https://doaj.org/article/5b18d82fcd5a4cef889f176dd0818c9c
Autor:
WonHee Kim, Liang Ma, Selene Lomoio, Rachel Willen, Sylvia Lombardo, Jinghui Dong, Philip G. Haydon, Giuseppina Tesco
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2018)
Abstract Background β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the rate-limiting enzyme in the production of amyloid beta (Aβ), the toxic peptide that accumulates in the brains of Alzheimer’s disease (AD) patients. Our previous
Externí odkaz:
https://doaj.org/article/7258624d78f2453a9df25d037112256f
Autor:
Moritz Armbruster, Saptarnab Naskar, Jacqueline P. Garcia, Mary Sommer, Elliot Kim, Yoav Adam, Philip G. Haydon, Edward S. Boyden, Adam E. Cohen, Chris G. Dulla
Publikováno v:
Nature Neuroscience. 25:607-616
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f34587797d45ca154da1b7a347143088
https://doi.org/10.1038/s41593-022-01049-x
https://doi.org/10.1038/s41593-022-01049-x
Autor:
Jerome Clasadonte, Lydie Morel, Camila M. Barrios-Camacho, Ming Sum R. Chiang, Jinhua Zhang, Lakshmanan Iyer, Philip G. Haydon, Yongjie Yang
Publikováno v:
Neurobiology of Disease, Vol 91, Iss , Pp 315-325 (2016)
Astroglia, the most abundant glial cells in the mammalian central nervous system (CNS), are considered an emerging key player in seizure induction and progression. Although astrocytes undergo reactive gliosis in temporal lobe epilepsy (TLE) with dram
Externí odkaz:
https://doaj.org/article/2dca29ec442d48bd82e76f712b062908
Autor:
Selene Lomoio, Ravi S. Pandey, Nicolas Rouleau, Beatrice Menicacci, WonHee Kim, William L. Cantley, Philip G. Haydon, David A. Bennett, Tracy L. Young-Pearse, Gregory W. Carter, David L. Kaplan, Giuseppina Tesco
BackgroundCurrent models to study Alzheimer’s disease (AD) include cell cultures and animal models. Human diseases, however, are often poorly reproduced in animal models. Developing techniques to differentiate human brain cells from induced pluripo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0df38cc1e2d0dcc039217844e20f208d
https://doi.org/10.1101/2022.07.21.501004
https://doi.org/10.1101/2022.07.21.501004
Autor:
Kendall R Walker, Amit Modgil, David Albrecht, Selene Lomoio, Philip G Haydon, Stephen J Moss, Giuseppina Tesco
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155799 (2016)
Golgi-localized γ-ear-containing ARF binding protein 3 (GGA3) is a monomeric clathrin adaptor that has been shown to regulate the trafficking of the Beta-site APP-cleaving enzyme (BACE1), which is required for production of the Alzheimer's disease (
Externí odkaz:
https://doaj.org/article/f97a36937c584f06ae853a52e5cb0fbf
Autor:
Shefeeq M. Theparambil, Noemí Esteras, Philip G. Haydon, Patrick S. Hosford, Anna Hadjihambi, Anja G. Teschemacher, Alla Korsak, Mark F. Lythgoe, Egor A. Turovsky, Nephtali Marina, Alexander V. Gourine, Yichao Yu, Alice Braga
Publikováno v:
The Journal of Neuroscience
Teschemacher, A G 2020, ' Mechanosensory signalling in astrocytes ', Journal of Neuroscience . https://doi.org/10.1523/JNEUROSCI.1249-20.2020
Teschemacher, A G 2020, ' Mechanosensory signalling in astrocytes ', Journal of Neuroscience . https://doi.org/10.1523/JNEUROSCI.1249-20.2020
Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048d950691e1f343934537a3549a6335
http://europepmc.org/articles/PMC7724146
http://europepmc.org/articles/PMC7724146
Autor:
Michael M. Halassa, Marco Dal Maschio, Riccardo Beltramo, Philip G. Haydon, Fabio Benfenati, Tommaso Fellin
Publikováno v:
The Scientific World Journal, Vol 10, Pp 1634-1645 (2010)
Although astrocytes are increasingly recognized as important modulators of neuronal excitability and information transfer at the synapse, whether these cells regulate neuronal network activity has only recently started to be investigated. In this art
Externí odkaz:
https://doaj.org/article/ca6161589a9b43ae9ac98e954c7a05e9
Publikováno v:
The Scientific World Journal, Vol 7, Pp 89-97 (2007)
Though accumulating evidence shows that the metabotropic glutamate receptor 5 (mGluR5) mediates some of the actions of extracellular glutamate after cocaine use, the cellular events underlying this action are poorly understood. In this review, we wil
Externí odkaz:
https://doaj.org/article/08056a81e3d94752973b715d904db3c9