Zobrazeno 1 - 10
of 26
pro vyhledávání: '"G H Wong"'
Autor:
Daniel P. G. H. Wong, Benjamin H. Good
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Gut microbiota can adapt to their host environment by rapidly acquiring new mutations. However, the dynamics of this process are difficult to characterize in dominant gut species in their complex in vivo environment. Here we show that the fi
Externí odkaz:
https://doaj.org/article/2c7cd8140f834c6898bdacf61f417448
Autor:
G H Wong, D V Goeddel
Publikováno v:
The Journal of Immunology. 152:1751-1755
The Fas Ag and the p55 TNF receptor (TNF-R1) are related molecules that can signal apoptosis. Some tumor cell lines are selectively killed by Fas activation and others by TNF-R1 activation even though both receptors are often co-expressed. TNF-R1-med
Publikováno v:
The Journal of Immunology. 151:4248-4257
In rat hepatoma H-35 cells, TNF-alpha, like IL-1 beta, stimulates the synthesis and secretion of type 1 acute phase plasma proteins, including alpha 1-acid glycoprotein (AGP), complement component 3 (C3), hemopexin, and haptoglobin. TNF and IL-1 in c
Publikováno v:
The Journal of Immunology. 149:3350-3353
Agonist antibodies (Ab) to the two TNF receptors, TNF-R1 (55 kDa) and TNF-R2 (75 kDa), have been shown to signal many of the distinct functions induced by TNF-alpha. We have found that anti-TNF-R1, but not anti-TNF-R2, Ab trigger antiviral activity i
Autor:
David Venzon, Jeffrey A. Norton, G. G. H. Wong, Douglas L. Fraker, Gerard M. Doherty, H R Alexander
Publikováno v:
The Journal of Experimental Medicine
Differentiation factor (D factor), also called leukemia inhibitory factor (LIF), is a glycoprotein that has been increasingly recognized to possess a wide range of physiological activities. We examined the possibility that the administration of D fac
Publikováno v:
EXS. 77
Tumor necrosis factor (TNF) and lymphotoxin (LT) are related cytokines produced in response to infection or oxidative insults such as radiation. These cytokines bind to the same receptors and have pleiotropic effects on a variety of cell types. TNF o
Publikováno v:
Journal of cellular biochemistry. 60(1)
Tumor necrosis factor (TNF) and lymphotoxin (LT), initially described as tumoricidal proteins, may be useful as adjuncts in cancer therapy. Treatment with TNF or LT was found to protect cells and animals against damage mediated by radiation or cytoto
Publikováno v:
Microsurgery. 17(3)
The effect of lymphotoxin (LT) on the functional recovery of crushed peripheral nerves was studied. Using a specially designed compression device, a 5 mm segment of the right sciatic nerve of rats was subjected to a 100 g crush load with a 2 hr durat
Publikováno v:
The Journal of Immunology. 140:4217-4223
We have examined the effects of transforming growth factor-beta (TGF-beta 1) on the expression of the class II histocompatibility Ag, HLA-DR: 1) induced by human rIFN-gamma (rHuIFN-gamma) in human melanoma, Hs294T cells and 2) constitutively expresse
Publikováno v:
The Journal of Immunology. 132:1361-1369
Metabolic labeling and immunoprecipitation with monoclonal antibodies, showed that lines of T-dependent mast cells (P cells) that were cultured in the absence of interferon-gamma (IFN-gamma) did not synthesize detectable amounts of Ia antigens or the