Zobrazeno 1 - 10
of 107
pro vyhledávání: '"G H Morrison"'
Autor:
G H Morrison, Subhash Chandra, Elena V. Usova, A. J. Lunato, Weihua Ji, Q Li, Werner Tjarks, C Boyer, Jianghai Wang, Staffan Eriksson, Jin-Cong Zhuo, Guirec Y. Cosquer
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:695-698
Several N-3 substituted carboranyl Thd analogs were synthesized. These agents as well as some non-boronated nucleosides were evaluated in phosphoryl transfer assays with recombinant human TK1 and TK2. For some carboranyl thymidine analogs, TK1 phosph
Autor:
G H, Morrison
Publikováno v:
Canadian Medical Association journal. 88(26)
Autor:
G H, Morrison
Publikováno v:
Canadian Medical Association journal. 82(18)
Publikováno v:
Anticancer research. 21(4A)
Selective accumulation of boron-10 isotope in the nuclei of cancer cells is pivotal to the success of Boron Neutron Capture Therapy (BNCT). Sophisticated microanalytical techniques are needed for checking the selectivity and boron delivery characteri
Publikováno v:
Cancer research. 56(19)
Boron neutron capture therapy (BNCT), a binary treatment modality that can potentially irradiate tumor tissue within cellular dimensions, is critically dependent on the preferential delivery of 10B to individual neoplastic cells. In this study, ion m
Publikováno v:
Radiation research. 140(1)
A well-characterized in vitro cryogenic preparation for ion microscopic isotope imaging, which minimizes redistribution of diffusible species, was used to determine the distribution of boron in GS-9L gliosarcoma cells incubated with the boron neutron
Publikováno v:
The Journal of biological chemistry. 269(21)
Ion microscopy was employed to investigate intracellular total calcium concentrations and calcium influx, and efflux in resting and antigen-stimulated tumor mast cells (RBL-2H3 cells). The nucleus, a perinuclear region which included the Golgi appara
Publikováno v:
Scanning microscopy. Supplement. 8
Ion microscopy, a mass spectrometry based isotopic imaging technique, is uniquely suited for ion transport related problems in biological systems. Due to its high sensitivity, it can image the transport and distribution of both major and minor elemen
Publikováno v:
Cancer research. 52(19)
The effectiveness of boron neutron capture therapy is predicted to be dependent not only on the amount of boron taken up by the target cells but also on the intracellular distribution of boron. Using the isotopic imaging technique ion microscopy, we
Autor:
G A, Valaskovic, G H, Morrison
Publikováno v:
Scanning microscopy. 6(2)
A short review of recent efforts being made in the quantification of images in ion microscopy is given. Special aspects of instrumentation, detection and acquisition, which are unique to direct imaging secondary ion mass spectrometry, are discussed i