Zobrazeno 1 - 10
of 22
pro vyhledávání: '"G H, Sunshine"'
Publikováno v:
Immunology. 94:513-522
In vivo anergy can be modelled by administration of soluble peptide to T-cell receptor (TCR) transgenic mice specific for the moth cytochrome c peptide 88-103 (MCCp). Two weeks after initial peptide treatment, T cells were present in normal numbers b
Publikováno v:
The Journal of Experimental Medicine
We have examined the requirements for activating unprimed T cells in vivo by transferring T cells into scid mice, which lack mature B and T cells. Purified adult thymocytes and a protein antigen, keyhole limpet hemocyanin (KLH), were injected into sc
Autor:
E A, Leadbetter, C R, Bourque, B, Devaux, C D, Olson, G H, Sunshine, S, Hirani, B P, Wallner, D E, Smilek, M P, Happ
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(1)
Multiple sclerosis is an autoimmune disease of the central nervous system in which T cell reactivity to several myelin proteins, including myelin basic protein (MBP), proteolipid protein, and myelin oligodendrocyte glycoprotein (MOG), has been implic
Publikováno v:
The Journal of Experimental Medicine
In the presence of the soluble polypeptide antigens ovalbumin and keyhole limpet hemocyanin, purified mouse spleen dendritic cells induce the secretion of IL-2 by antigen-specific T cell hybridomas. This response is H-2 restricted and can be specific
Publikováno v:
The Journal of Immunology. 132:1728-1734
A mechanism responsible for the induction of NP-specific first order (inducer) suppressor cells (TS1) is described. TS1 cells are induced by i.v. administration of hapten-coupled splenic cells. Their activity is assessed by the adoptive transfer of N
Publikováno v:
The Journal of Immunology. 133:1137-1141
Third-order (Ts3) suppressor cells are generated after conventional immunization. These cells, however, will not mediate suppressor cell function unless specifically triggered by an activating signal, termed TsF2. This report analyzes the mechanism o
Publikováno v:
The Journal of Immunology. 130:546-550
Murine cortisone-resistant thymocytes were separated by staining with monoclonal anti-Lyt-2 antibody and FMF into Lyt-2- and Lyt-2+ subsets in order to analyze the nature of stimulator accessory cells required to activate each of these functionally d
Publikováno v:
Nature New Biology. 230:133-136
Binding sites on intracellular membranes in rat fiver cells seem to be sex specific. Activation of isolated endoplasmic reticulum depends on oestradiol in the male, and on testosterone in the female.
Publikováno v:
Cellular immunology. 93(2)
We have used a fractionation procedure involving bovine serum albumin gradient floatation, adherence to glass, and rosetting with antibody-coated sheep erythrocytes to purify an accessory cell fraction from Lewis rat spleens. The fraction which is of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 132(4)
A mechanism responsible for the induction of NP-specific first order (inducer) suppressor cells (TS1) is described. TS1 cells are induced by i.v. administration of hapten-coupled splenic cells. Their activity is assessed by the adoptive transfer of N