Zobrazeno 1 - 10
of 53
pro vyhledávání: '"G H, Rothblat"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 11, Pp 2264-2272 (1997)
Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid cholesterol depletion. In the present study, we have developed experimental systems for using solutions of cyclodextrins,
Externí odkaz:
https://doaj.org/article/5e0700f6b3af43719c50722ff4a353eb
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 9, Pp 2041-2051 (1996)
Oxysterols arising from the diet or through lipid peroxidation may be important in the modulation of cellular cholesterol metabolism. In this study, the metabolism of one of the oxysterols, 25-hydroxycholesterol (25OHC), was examined in J774 and mous
Externí odkaz:
https://doaj.org/article/1e67672c09bb45a3aeef33c608851c5a
Autor:
N Fournier, M de la Llera Moya, B F Burkey, J B Swaney, J. Paterniti, Jr., N Moatti, V Atger, G H Rothblat
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 8, Pp 1704-1711 (1996)
Sera of transgenic rats expressing human apoA-I were tested for their ability to stimulate efflux of radiolabeled cholesterol from Fu5AH rat hepatoma cells. Expression of human apoA-I resulted in a dose-dependent increase in HDL, as measured by both
Externí odkaz:
https://doaj.org/article/3af3bcbd889e4e23aa94a7fe8deb9e78
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 3, Pp 505-516 (1995)
The effect of oxysterols on efflux of cholesterol from mouse L-cell fibroblasts, rat Fu5AH hepatoma cells, J774 macrophages, and human EA.hy 926 endothelial cells was studied. Cells were preincubated with 25-hydroxycholesterol (25-OHC) either during
Externí odkaz:
https://doaj.org/article/c81d2dc251cc49c4bd8580144c11b7a5
Autor:
R.K. Tangirala, W.G. Jerome, N.L. Jones, D M Small, W J Johnson, J M Glick, F H Mahlberg, G H Rothblat
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 1, Pp 93-104 (1994)
In a previous study using the J774 macrophage foam cells, we quantitated the accumulation of unesterified (free) cholesterol derived from cholesteryl ester hydrolysis in lysosomes, after phagocytic uptake of cholesteryl ester droplets. In the present
Externí odkaz:
https://doaj.org/article/5e3c37eb3af64a6f90aa1942b4b170d7
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 3, Pp 350-358 (1978)
Human high density lipoprotein enriched in free cholesterol was obtained by exposing the lipoprotein to lipid dispersions having a free cholesterol/lecithin molar ratio greater than two. The metabolism of cholesterol was studied in tissue culture cel
Externí odkaz:
https://doaj.org/article/5d2aced2a655455da57a2bb4f3113a30
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 7, Pp 869-876 (1983)
The objective of this study was to determine whether high density lipoproteins (HDL) that have been treated with hepatic lipase have an enhanced ability to deliver cholesterol to cells. Human HDL was incubated with rat hepatic lipase, reisolated, and
Externí odkaz:
https://doaj.org/article/38b6fe80d7624957ae188cf0c9bb29a4
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 2, Pp 189-197 (1989)
Cultured rabbit aortic smooth muscle cells were converted to foam cells by exposure to sonicated lipid droplets of defined composition using an inverted culture technique. Uptake of the lipid droplets by the cells was shown to be dependent on the tim
Externí odkaz:
https://doaj.org/article/bbb267976b9f47eda45babaf82115870
Autor:
M, de La Llera-Moya, M A, Connelly, D, Drazul, S M, Klein, E, Favari, P G, Yancey, D L, Williams, G H, Rothblat
Publikováno v:
Journal of lipid research. 42(12)
Results from several laboratories clearly indicate that expression of scavenger receptor class B type I (SR-BI) enhances the bidirectional flux of cholesterol between cells and lipoproteins. Because the activity of HMG-CoA reductase, the key enzyme i
Autor:
A E, Christian, H S, Byun, N, Zhong, M, Wanunu, T, Marti, A, Fürer, F, Diederich, R, Bittman, G H, Rothblat
Publikováno v:
Journal of lipid research. 40(8)
Previous studies from this laboratory have demonstrated that low concentrations of cyclodextrins (1.0 mm), when added to serum, act catalytically as cholesterol shuttles to accelerate the exchange of free cholesterol between cells and serum lipoprote