434 Correlation of endometrial tumor DNA mismatch repair status and MELF-pattern invasion

Autor: E Kertowidjojo, C DiNobile, Michael L. Pearl, W Burke, G Gossner, X Wen, C Tornos

Publikováno v: Poster.

Introduction Endometrial adenocarcinoma is the most common gynecologic malignancy in the United States. Between 10–30% of endometrial adenocarcinomas exhibit microsatellite instability (MSI), a type of genetic hypermutability that results from impa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a5735cf6fb6d2f239e61d1ce75983d9
https://doi.org/10.1136/ijgc-2020-igcs.376

The effect of PrP Sc accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue

Autor: Anton G. Gossner, John Hopkins

Publikováno v: Veterinary Microbiology
Gossner, A G & Hopkins, J 2015, ' The effect of PrP(Sc) accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue ', Veterinary Microbiology, vol. 181, no. 3-4, pp. 204-211 . https://doi.org/10.1016/j.vetmic.2015.10.013

Highlights • Arrays quantified gene expression in peripheral LNs during sheep scrapie. • Disease progression associated with alterations of inflammatory gene expression. • Lymph node response contrasts with response of CNS. • Step changes to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77036cb37ca6c00e7369103e8238fbb4

Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie

Autor: Anton G. Gossner, Jim D. Foster, John K. Fazakerley, Nora Hunter, John Hopkins

Publikováno v: Gossner, A G, Foster, J D, Fazakerley, J K, Hunter, N & Hopkins, J 2011, ' Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie ', Veterinary Microbiology, vol. 147, no. 1-2, pp. 42-48 . https://doi.org/10.1016/j.vetmic.2010.05.043

Rodent scrapie models have been exploited to define the molecular basis for the progression of neuropathological changes in TSE diseases. We aim to assess whether CNS gene expression changes consistently observed in mouse models are of generic releva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8972c467ca0ca63ac4a0a56dd399d4bd
https://doi.org/10.1016/j.vetmic.2010.05.043

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Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response

Autor: Anton G Gossner, Virginia M Venturina, Darren J Shaw, Josephine M Pemberton, John Hopkins

Publikováno v: Gossner, A G, Venturina, V M, Shaw, D J, Pemberton, J M & Hopkins, J 2012, ' Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response ', Veterinary Research, vol. 43, no. 1, 26, pp.-. https://doi.org/10.1186/1297-9716-43-26
Veterinary Research
Veterinary Research, Vol 43, Iss 1, p 26 (2012)

Teladorsagia circumcincta is the most economically important gastrointestinal (abomasal) nematode parasite of sheep in cool temperate regions, to which sheep show genetically-varying resistance to infection. Lambs, from parents with genetic variation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf40f39b77b98c8c9f3d8d286ba395b
https://www.pure.ed.ac.uk/ws/files/7605484/BMC_2012_Pemberton.pdf