Zobrazeno 1 - 10
of 372
pro vyhledávání: '"G Goglia"'
Autor:
Agnieszka A. Gil, César Carrasco-López, Liyuan Zhu, Evan M. Zhao, Pavithran T. Ravindran, Maxwell Z. Wilson, Alexander G. Goglia, José L. Avalos, Jared E. Toettcher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The ability to regulate nanobody affinity with light would expand the applications toolbox for these reagents. Here the authors insert an optimised photoswitchable AsLOV2 domain into multiple nanobodies and demonstrate photoswitchable binding to fluo
Externí odkaz:
https://doaj.org/article/0efe65320d7b472997bd875d0dcd862e
Autor:
Praveen Pendyala, MD, Alexander G. Goglia, PhD, Malcolm D. Mattes, MD, Alison Grann, MD, David Huang, MD, Raquel T. Wagman, MD, Zeinab Abou Yehia, MD, Jennifer Yoon, MD, Ronald D. Ennis, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 3, Pp 100680- (2021)
Purpose: This study aimed to define how the coronavirus disease of 2019 (COVID-19) pandemic affected the role, timing, and delivery of radiation therapy (RT) in a high-prevalence region at the height of the initial U.S. outbreak. Methods and Material
Externí odkaz:
https://doaj.org/article/a0a6b6d1976043c08a5e3c4ec2f54b2d
Autor:
N. Ari Wijetunga, Alexander G. Goglia, Nils Weinhold, Michael F. Berger, Michael Cislo, Daniel S. Higginson, Kiana Chabot, Ahmed M. Osman, Lauren Schaff, Elena Pentsova, Alexandra M. Miller, Simon N. Powell, Adrienne Boire, Jonathan T. Yang
Publikováno v:
Clinical Cancer Research. 29:775-783
Purpose:Proton craniospinal irradiation (pCSI) is a promising treatment for patients with solid tumor leptomeningeal metastasis (LM). We hypothesize that genetic characteristics before and changes resulting after pCSI will reflect clinical response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b42fa98bc9483c6a1456f1f64be287
https://doi.org/10.1158/1078-0432.ccr-22-2434
https://doi.org/10.1158/1078-0432.ccr-22-2434
Publikováno v:
Case Reports in Nephrology, Vol 2020 (2020)
Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis. While the lungs and kidneys are the major organs affected by MPA, it is known to involve multiple organ systems throughout the body. Temporal art
Externí odkaz:
https://doaj.org/article/7a83c6972876453183f81fc4151ffd24
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Results for each of the 16 identified hits in the panel of IR foci formation assays, and additional clonogenic survival data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2413ea7aafb134ab76274203272711
https://doi.org/10.1158/1535-7163.22503628
https://doi.org/10.1158/1535-7163.22503628
Autor:
Charles L. Sawyers, Simon N. Powell, Jayanta Chaudhuri, Maria Jasin, Michael J. Zelefsky, Peter T. Scardino, John Wongvipat, Haley Hieronymus, Anuradha Gopalan, Alexander G. Goglia, Sho Fujisawa, Neel P. Shah, Philip A. Watson, Yu Chen, Brett S. Carver, Deyou Zheng, Ling Cai, Wei-Feng Yen, Vivek K. Arora, Phillip J. Iaquinta, Daniel E. Spratt, Elizabeth M. Kass, Man X. Lee, Joel S. Parker, William R. Polkinghorn
Supplementary Figure S1 - PDF file 1194K, Gamma-H2AX foci and Comet assay normalized of LNCaP plus or minus androgen normalized to time 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e77594a6f2297abd44d8b914566fc28
https://doi.org/10.1158/2159-8290.22529294.v1
https://doi.org/10.1158/2159-8290.22529294.v1
Autor:
Charles L. Sawyers, Simon N. Powell, Jayanta Chaudhuri, Maria Jasin, Michael J. Zelefsky, Peter T. Scardino, John Wongvipat, Haley Hieronymus, Anuradha Gopalan, Alexander G. Goglia, Sho Fujisawa, Neel P. Shah, Philip A. Watson, Yu Chen, Brett S. Carver, Deyou Zheng, Ling Cai, Wei-Feng Yen, Vivek K. Arora, Phillip J. Iaquinta, Daniel E. Spratt, Elizabeth M. Kass, Man X. Lee, Joel S. Parker, William R. Polkinghorn
Supplementary Table S2 - PDF file 250K, Defining AR-regulated DNA repair genes in LNCaP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e9824254a57dbcbbfe87a6194f0ac0
https://doi.org/10.1158/2159-8290.22529276.v1
https://doi.org/10.1158/2159-8290.22529276.v1
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
HR and mNHEJ results of the high-throughput screen presented as a 2D RADaR plot.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affcfc049296b668007e6b53f1e5e578
https://doi.org/10.1158/1535-7163.22503646.v1
https://doi.org/10.1158/1535-7163.22503646.v1
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Additional data for hits from the primary screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862ddc972d914ec15877873254bb58fd
https://doi.org/10.1158/1535-7163.22503625
https://doi.org/10.1158/1535-7163.22503625
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Additional cell-based DSB repair assay optimization studies in preparation for high-throughput screening.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f6558e3af8443e735e7eadca176f48
https://doi.org/10.1158/1535-7163.22503649
https://doi.org/10.1158/1535-7163.22503649