Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development

Autor: Dagmar Rudzki, Xavier Montalban, Antonio Bertolotto, Florian Deisenhammer, Finn Sellebjerg, Raija L.P. Lindberg, Matthias Mehling, Per Soelberg Sørensen, Michael Khalil, Michael Guger, G Giovanonni, Chris H. Polman, Joep Killestein, Simona Malucchi, Franz Schautzer, Alban Millonig, Harald Hegen, Martina Hoelzl, Manuel Comabella

Publikováno v: Multiple Sclerosis, 20(5), 577-587. SAGE Publications Ltd
Hegen, H, Millonig, A, Bertolotto, A, Comabella, M, Giovanonni, G, Guger, M, Hoelzl, M, Khalil, M, Killestein, J, Lindberg, R, Malucchi, S, Mehling, M, Montalban, X, Polman, C H, Rudzki, D, Schautzer, F, Sellebjerg, F, Sorensen, P S & Deisenhammer, F 2014, ' Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development ', Multiple Sclerosis, vol. 20, no. 5, pp. 577-587 . https://doi.org/10.1177/1352458513503597

Background: Neutralizing antibodies (NAb) affect efficacy of interferon-beta (IFN-b) treatment in multiple sclerosis (MS) patients. NAbs evolve in up to 44% of treated patients, usually between 6–18 months on therapy. Objectives: To investigate whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea6ad82a4f49b875c6c5bbd87e96376
https://doi.org/10.1177/1352458513503597

Primary diffuse leptomeningeal gliomatosis simulating tuberculous meningitis

Autor: N Balakas, J H Rees, T Revesz, M Luxsuwong, G Giovanonni, S F Hain, A Agathonikou, C P Panayiotopoulos

Publikováno v: Journal of neurology, neurosurgery, and psychiatry. 70(1)

Three patients are reported on who presented with communicating hydrocephalus due to presumed tuberculous meningitis. Subsequent clinical deterioration despite antituberculous chemotherapy prompted reassessment with FDG-PET scanning and meningeal bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0384381f7598be4f7201606ea5c61745
https://pubmed.ncbi.nlm.nih.gov/11118261

PND13 A COST-EFFECTIVENESS ANALYSIS OF NATALIZUMAB VS. INTERFERON-BETA AND GLATIRAMER ACETATE IN PATIENTS WITH ACTIVE RELAPSING-REMITTING MULTIPLE SCLEROSIS CURRENTLY FAILING ON EXISTING THERAPY

Autor: S Hughes, G Giovanonni, ER Samuels, R Gani

Publikováno v: Value in Health. 11:A140

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce9a57a1b5c5e4f3046b090d5b630b5
https://doi.org/10.1016/s1098-3015(10)70446-0

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