Zobrazeno 1 - 10
of 61
pro vyhledávání: '"G G Illei"'
Autor:
G G Illei, Howard A. Austin
Publikováno v:
Lupus. 14:65-71
Membranous lupus nephritis (MLN) represents about 20% of clinically significant renal disease in lupus. Few studies have addressed directly the pathogenesis of MLN. Our assumptions about the underlying mechanisms are based on the combination of extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546b6f480714f152cef5f694cb0cd303
https://doi.org/10.1191/0961203305lu2062oa
https://doi.org/10.1191/0961203305lu2062oa
Publikováno v:
Expert Opinion on Investigational Drugs. 10:1117-1130
In systemic lupus erythematosus hyperactive helper T-cells drive polyclonal B-cell activation and secretion of pathogenic auto-antibodies. The auto-antibodies form immune complexes with their respective auto-antigens, which in turn deposit in sites s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5d820191e8503ce77c16a62f85ec1f
https://doi.org/10.1517/13543784.10.6.1117
https://doi.org/10.1517/13543784.10.6.1117
Autor:
G G, Illei, J H, Klippel
Publikováno v:
Rheumatic Disease Clinics of North America. 26:63-73
The removal of pathologic humors by various methods is an ancient medical remedy used in the management of diseases whose pathophysiology is poorly understood and whose effective treatment modalities are lacking. The contemporary means for such an ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adb1795477ccf6b785f991982ee835f
https://doi.org/10.1016/s0889-857x(05)70120-4
https://doi.org/10.1016/s0889-857x(05)70120-4
Publikováno v:
Oral diseases. 18(4)
Patients with Sjögren's syndrome (SS) show aberrant expression of the B cell-related mediators, B cell-activating factor (BAFF), and a proliferation-inducing ligand (APRIL) in serum and salivary glands (SGs). We studied the biological effect of neut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5793ce2822fe67478b7e0b719a90af84
https://pubmed.ncbi.nlm.nih.gov/22212434
https://pubmed.ncbi.nlm.nih.gov/22212434
Publikováno v:
Oral diseases. 18(1)
Non-obese diabetic (NOD) mice develop an autoimmune exocrinopathy that shows similarities with Sjögren's syndrome. They provide an experimental model to study the pathoetiogenesis of this disease.Salivary gland (SG) function and salivary sodium cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5dc46ff0ff968fe61862fcb66f4fb52
https://pubmed.ncbi.nlm.nih.gov/21914088
https://pubmed.ncbi.nlm.nih.gov/21914088
Publikováno v:
Oral diseases. 18(2)
Sjögren's syndrome is a complex autoimmune disease of the salivary gland with an unknown etiology, so a thorough characterization of the transcriptome would facilitate our understanding of the disease. We use ultradeep sequencing of small RNAs from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab09aa75a40669fa233118643a8068fe
https://pubmed.ncbi.nlm.nih.gov/21895886
https://pubmed.ncbi.nlm.nih.gov/21895886
Publikováno v:
Oral diseases. 16(1)
The aim of this study was to examine the presence of microRNAs (miRNAs) within exosomes isolated from human saliva and to optimize and test methods for successful downstream applications.Exosomes isolated from fresh and frozen glandular and whole hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::318fb089e4196c1a4e2ae63cc149c939
https://pubmed.ncbi.nlm.nih.gov/19627513
https://pubmed.ncbi.nlm.nih.gov/19627513
Publikováno v:
Lupus. 10(3)
Aggressive immunosuppressive therapy with cyclophosphamidehas improved the outcome of major organ disease in lupus patients. Controlled trials have shown that pulse cyclophosphamide is the treatment of choice for patients with moderate to severe prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d4dd8ce8c641935558dc0046bce112
https://pubmed.ncbi.nlm.nih.gov/11315345
https://pubmed.ncbi.nlm.nih.gov/11315345
Publikováno v:
Arthritis and rheumatism. 43(6)
Monocyte-derived cytokines are important mediators in synovitis and represent novel therapeutic targets. This study was undertaken to analyze their expression in synovial membrane (SM) of patients with psoriatic arthritis (PsA) compared with that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::047b304567e3fefa2c6d3c0ae9b05067
https://pubmed.ncbi.nlm.nih.gov/10857783
https://pubmed.ncbi.nlm.nih.gov/10857783
Autor:
J H Klippel, G G Illei
Publikováno v:
Lupus. 7(9)
Lupus nephritis can be managed successfully in the majority of cases; most therapies, however, are associated with significant side-effects. Several new agents aiming at specific stages in the pathogenesis of lupus are in different phases of clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a075c6f541ab3bd913d8c3a9c4bbcb17
https://pubmed.ncbi.nlm.nih.gov/9884104
https://pubmed.ncbi.nlm.nih.gov/9884104