Výsledky vyhledávání

Deducing the organization of a transmembrane domain by disulfide cross-linking. The bacterial chemoreceptor Trg

Autor: M R Lebert, D P Dutton, G G Burrows, Gerald L. Hazelbauer, Geoffrey F. Lee

Publikováno v: Journal of Biological Chemistry. 269:29920-29927

The transmembrane domain of chemoreceptor Trg from Escherichia coli contains four segments, two from each subunit of the homodimer. We used site-specific mutagenesis to introduce cysteines into those segments and oxidative cross-linking of cysteine p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91dd5cde23538258658b235016e69833
https://doi.org/10.1016/s0021-9258(18)43969-5

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Human TCR as antigen: homologies and potentially cross-reactive HLA-DR2-restricted epitopes within the AV and BV CDR2 loops

Autor: A A, Vandenbark, N, Culbertson, T, Finn, D, Barnes, A, Buenafe, G G, Burrows, S, Law, Y K, Chou, H, Offner

Publikováno v: Critical reviews in immunology. 20(1)

The major function of the T-cell receptor is to confer antigen specificity to T cells. However, nascent TCR proteins that are not assembled into functional heterodimers may be processed and displayed with self MHC molecules on the T-cell surface, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8cb647e2188d943b1394ba0ce73488ff
https://pubmed.ncbi.nlm.nih.gov/10770270

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Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis

Autor: G G, Burrows, B F, Bebo, K L, Adlard, A A, Vandenbark, H, Offner

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(11)

We designed and expressed in bacteria a single-chain two-domain MHC class II molecule capable of binding and forming stable complexes with antigenic peptide. The prototype "beta1alpha1" molecule included the beta1 domain of the rat RT1.B class II mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b559f04cd4640d309b07d3c8f96a5d6d
https://pubmed.ncbi.nlm.nih.gov/9834080

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Vaccination with BV8S2 protein amplifies TCR-specific regulation and protection against experimental autoimmune encephalomyelitis in TCR BV8S2 transgenic mice

Autor: H, Offner, K, Adlard, B F, Bebo, J, Schuster, G G, Burrows, A C, Buenafe, A A, Vandenbark

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(5)

TCR determinants overexpressed by autopathogenic Th1 cells can naturally induce a second set of TCR-specific regulatory T cells. We addressed the question of whether immune regulation could be induced naturally in a genetically restricted model in wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::941c18d951212e0c48bc3985bbc5c63e
https://pubmed.ncbi.nlm.nih.gov/9725209

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Multiple class I motifs revealed by sequencing naturally processed peptides eluted from rat T cell MHC molecules

Autor: G G, Burrows, K, Ariail, B, Celnik, J E, Gambee, H, Offner, A A, Vandenbark

Publikováno v: Journal of neuroscience research. 49(1)

Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides. Displayed on the cell surface, the class I/peptide complex provides an extracellular indication of the intracellular milieu. We have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac380620bb5d457c2ee413052f648e92
https://pubmed.ncbi.nlm.nih.gov/9211995

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Variation in H-2K(k) peptide motif revealed by sequencing naturally processed peptides from T-cell hybridoma class I molecules

Autor: G G, Burrows, K, Ariail, B, Celnik, J E, Gambee, B F, Bebo, H, Offner, A A, Vandenbark

Publikováno v: Journal of neuroscience research. 45(6)

Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides, displaying them on the cell surface and providing an extracellular indication of intracellular invasion. The most clearly defined rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65a4b4074727c84ffeaf228245e8c886
https://pubmed.ncbi.nlm.nih.gov/8892092

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Neonatal injection of Lewis rats with recombinant V beta 8.2 induces T cell but not B cell tolerance and increased severity of experimental autoimmune encephalomyelitis

Autor: M, Vainiene, G G, Burrows, K, Ariail, I, Robey, A A, Vandenbark, H, Offner

Publikováno v: Journal of neuroscience research. 45(4)

In Lewis rats with experimental autoimmune encephalomyelitis (EAE) mediated by V beta 8.2 effector cells, anti-idiotypic T cells and antibodies could be boosted by injection of V beta 8.2 peptides, inducing both T cells and antibodies that reduced th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a576c037d76b33b2217bd04d1a312320
https://pubmed.ncbi.nlm.nih.gov/8872909

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Deducing the organization of a transmembrane domain by disulfide cross-linking. The bacterial chemoreceptor Trg

Autor: G F, Lee, G G, Burrows, M R, Lebert, D P, Dutton, G L, Hazelbauer

Publikováno v: The Journal of biological chemistry. 269(47)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57d6670d4c02e729eb6813a24652ddf4
https://pubmed.ncbi.nlm.nih.gov/7961989

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Purification of Receptor Protein Trg by Exploiting a Property Common to Chemotactic Transducers of Escherichia coli

Autor: G G Burrows, M E Newcomer, Gerald L. Hazelbauer

Publikováno v: Journal of Biological Chemistry. 264:17309-17315

The methyl-accepting chemotactic transducers of Escherichia coli were found to bind strongly to Cibacron blue-Sepharose. Among potential elutants tested, only S-adenosylmethionine at moderate concentrations and NaCl at concentrations greater than 1.5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3c0edcd79bcb3cc6f6cc31b569bb71a
https://doi.org/10.1016/s0021-9258(18)71493-2

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Akademický článek

Accidental ice-burn.

Autor: Stagnell S, Burrows G

Publikováno v: British dental journal [Br Dent J] 2016 Aug 26; Vol. 221 (4), pp. 149.

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