Zobrazeno 1 - 10
of 43
pro vyhledávání: '"G G, Yarbrough"'
Autor:
G G, Yarbrough, D P, Taylor
Publikováno v:
Journal of the Royal College of Physicians of London. 25(4)
Modern technology applied to the study of receptor proteins has revealed that distinct structural domains of these molecules subserve different functions. With many receptors it is known that a soluble, extracellular portion of the molecule is respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe02737b692f5df10e139be2a87fda97
https://pubmed.ncbi.nlm.nih.gov/1960687
https://pubmed.ncbi.nlm.nih.gov/1960687
Autor:
G G Yarbrough
Publikováno v:
Life Sciences. 33:111-118
The centrally mediated pharmacological effects of thyrotropin releasing hormone (TRH), their mechanistic basis and therapeutic implications, along with the possible physiological significance of extrahypothalamic TRH, have been the subject of numerou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc45757a7b6712cc0cb8ae53fba45bec
https://doi.org/10.1016/0024-3205(83)90403-4
https://doi.org/10.1016/0024-3205(83)90403-4
Publikováno v:
Journal of Pharmacological Methods. 11:187-193
Xylazine causes a dose-related loss of the righting reflex (LRR) in mice when combined with a subanesthetic dose of chloral hydrate. Compounds that preferentially block alpha 2-adrenoceptors antagonize this xylazine plus chloral hydrate LRR at low do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18c0715b9b5543dc22a5d518895ae3f3
https://doi.org/10.1016/0160-5402(84)90037-8
https://doi.org/10.1016/0160-5402(84)90037-8
Autor:
Dilip K. Singh, Jodie McGuffin-Clineschmidt, D. R. Haubrich, Gregory E. Martin, Robert J. Bendesky, G G Yarbrough
Publikováno v:
European Journal of Pharmacology. 99:73-78
The rank order of potency to activate central dopamine autoreceptors of seven compounds known to possess central nervous system dopamine agonist activity were assessed with the following techniques: (1) inhibition of dopaminergic neuronal firing in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec2c5f8bbdcf8c69dead51698773e24
https://doi.org/10.1016/0014-2999(84)90433-3
https://doi.org/10.1016/0014-2999(84)90433-3
Autor:
G K Kostopoulos, G G Yarbrough
Publikováno v:
Journal of Pharmacy and Pharmacology. 27:408-412
The effects of microiontophoretic applications of equivalent doses (ejection times and currents) of noradrenaline, amphetamine, octop-amine and p-hydroxynorephedrine on the spontaneous firing of Purkinje and unidentified cells in the cerebellum of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811558c4478c38151a191e159f6ceaf0
https://doi.org/10.1111/j.2042-7158.1975.tb09469.x
https://doi.org/10.1111/j.2042-7158.1975.tb09469.x
Publikováno v:
Psychopharmacology. 70:145-148
Thyrotropin-releasing hormone (TRH) and a structurally related analogue of TRH, MK-771, administered IP or orally, restored flex or reflex activity in rats with acute spinal transections. The effect of MK-771 in this test was not modified by pretreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862fe70f2b42fe36b440858b7b4dd44e
https://doi.org/10.1007/bf00435305
https://doi.org/10.1007/bf00435305
Autor:
C. Wong, G. G. Yarbrough
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 53:509-512
The effects of pretreatments with various doses of glutamic acid diethyl or dimethyl esters on morphine-induced anti-nociception in the hot-plate and tail-flick tests on rats were examined. While neither substance alone altered control reaction times
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b578dde4a7a042bc889429be9676a62a
https://doi.org/10.1139/y75-072
https://doi.org/10.1139/y75-072
Autor:
G. G. Yarbrough
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 56:443-446
Iontophoretically applied muscimol exerted a potent inhibitory action on the firing of spontaneously active cerebral cortical neurons of rats. On the basis of ejection currents employed, muscimol was considerably more potent than γ-aminobutyric acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b5e6f4751654ba1f39255be96de2d3
https://doi.org/10.1139/y78-066
https://doi.org/10.1139/y78-066
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 61:764-766
Comparisons among spontaneously hypertensive (SHR), Kyoto Wistar (KW), and Wistar (W) rats were made of the functional states of central nervous system (CNS) α2-adrenoceptors (clonidine-induced mydriasis) and nonvascular peripheral presynaptic α2-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0628c2446c59491f8f36586b49ef59f
https://doi.org/10.1139/y83-118
https://doi.org/10.1139/y83-118
Autor:
D. K. Singh, G. G. Yarbrough
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 57:920-922
Topically applied MK-771 (pyro-2-aminoadipyl-histidyl-thiazolidine-4-carboxamide), a novel thyrotropin-releasing hormone (TRH) analog, was found to be equipotent with TRH in depolarizing the ventral roots of the isolated, hemisected amphibian (Bufo m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64054f1f228549dc30db6c84a28afd9c
https://doi.org/10.1139/y79-141
https://doi.org/10.1139/y79-141