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pro vyhledávání: '"G G, Sladek"'
Phase I study of a five-day dose schedule of 4-Ipomeanol in patients with non-small cell lung cancer
Autor:
V K, Kasturi, M P, Dearing, S C, Piscitelli, E K, Russell, G G, Sladek, K, O'Neil, G A, Turner, T L, Morton, M C, Christian, B E, Johnson, M J, Kelley
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(9)
The mammalian pulmonary toxin 4-ipomeanol (IPO) is activated by the cytochrome P450 system in bronchial Clara cells in animals. The resulting metabolites bind rapidly to macromolecules, producing localized cytotoxicity. IPO has in vitro and in vivo a
Autor:
Chute JP; Division of Hematology/Oncology, National Naval Medical Center, Bethesda, Maryland 20889-5600, USA., Ryan CP, Sladek G, Shakir KM
Publikováno v:
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 1997 Mar-Apr; Vol. 3 (2), pp. 77-9.
Publikováno v:
Arthritis and rheumatism [Arthritis Rheum] 1981 May; Vol. 24 (5), pp. 747.