Zobrazeno 1 - 10
of 111
pro vyhledávání: '"G G, Klaus"'
Publikováno v:
The Journal of Immunology. 159:1150-1159
B cell activation induced by cross-linking of CD40 is enhanced by costimulation with certain T cell-derived cytokines (generally Th2 type), most notably IL-4. We show here that the induction of DNA synthesis in normal mouse B cells by anti-CD40 mAb i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70630f3c8488abfee20237fd6f45a5bf
https://doi.org/10.4049/jimmunol.159.3.1150
https://doi.org/10.4049/jimmunol.159.3.1150
Publikováno v:
The Journal of Immunology. 152:2821-2829
Cross-linking of sIgM or sIgD receptors on mature B cells with appropriate anti-Ig Abs normally induces B cell activation and DNA synthesis. We show here that hypercross-linking of either class of sIg receptor on these cells by biotinylated, normally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5f9f55edde1ecc3aa960aa80d10c84
https://doi.org/10.4049/jimmunol.152.6.2821
https://doi.org/10.4049/jimmunol.152.6.2821
Publikováno v:
European journal of immunology. 29(10)
Protection against infection with encapsulated bacteria is mediated by IgG antibodies against the capsular polysaccharides. Production of such antibodies is impaired during infancy, when susceptibility to bacterial meningitis is greatest. Recent stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb7d3613e59a8f60d37dd2a66cc7cd07
https://pubmed.ncbi.nlm.nih.gov/10540333
https://pubmed.ncbi.nlm.nih.gov/10540333
Autor:
E W, Lam, J, Glassford, J, van der Sman, L, Banerji, A R, Pizzey, N, Shaun, B, Thomas, G G, Klaus
Publikováno v:
European journal of immunology. 29(10)
Since signals via CD40 and the B cell receptor are known to synergize to induce B cell activation, we have analyzed the pocket protein/E2F complexes in mouse B lymphocytes following stimulation by anti-IgM, anti-CD40, alone or together. We find that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e4b334f75743d0b27baf2541fa8b013
https://pubmed.ncbi.nlm.nih.gov/10540350
https://pubmed.ncbi.nlm.nih.gov/10540350
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
The interaction of CD40 on B cells with the CD40 ligand (CD40L) on preactivated CD4 T cells is critical for the initiation of T-dependent Ab responses. It is believed that signals via CD40 synergize with cytokines (e.g., IL-4 and IL-5) to drive B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9d9cde1b3b1512bf61d543ba8d4d433
https://pubmed.ncbi.nlm.nih.gov/9794390
https://pubmed.ncbi.nlm.nih.gov/9794390
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
The potent accessory properties of dendritic cells (DC) develop sequentially during a process termed "maturation." Splenic DC undergo functional maturation in vivo in response to the bacterial product LPS and migrate from the marginal zone to the T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8611b961ed59a4310b68973cbaafafb
https://pubmed.ncbi.nlm.nih.gov/9794369
https://pubmed.ncbi.nlm.nih.gov/9794369
Autor:
G G, Klaus
Publikováno v:
Seminars in immunology. 2(2)
Guanine nucleotide regulatory (G) proteins control signalling via a variety of widely distributed cell surface receptors. Relatively little is known about the involvement of G-proteins in signal transduction via biologically important receptors on ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf4444a320ba7a868953c9946c144829
https://pubmed.ncbi.nlm.nih.gov/2151799
https://pubmed.ncbi.nlm.nih.gov/2151799
Autor:
M K Bijsterbosch, G G Klaus
Publikováno v:
The Journal of Immunology. 137:1294-1299
Concanavalin A (Con A) induces DNA synthesis in bulk cultures of murine T cells. In contrast, the lectin has been shown to stimulate purified B cells to leave G0, but not to proliferate. We demonstrate here that Con A induces comparable increases in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72dda9f79aa2a8721170ddcd1503ad6b
https://doi.org/10.4049/jimmunol.137.4.1294
https://doi.org/10.4049/jimmunol.137.4.1294
Publikováno v:
The Journal of Immunology. 139:3924-3929
We have recently described three "immature" B cell lymphomas which are exquisitely sensitive to growth inhibition by anti-Ig reagents and may serve as models for tolerance induction in normal B cells. These cells are inhibited from cell cycle progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::991b6dfafacac75549157297a16f4321
https://doi.org/10.4049/jimmunol.139.12.3924
https://doi.org/10.4049/jimmunol.139.12.3924
Autor:
M M Harnett, G G Klaus
Publikováno v:
The Journal of Immunology. 140:3135-3139
Cross-linking of the IgM and IgD Ag-R on mature B lymphocytes provokes the rapid hydrolysis of phosphatidylinositol 4,5-bisphosphate. We show here that in permeabilized, [3H]inositol-labeled mouse B cells the nonhydrolyzable GTP analogue GTP gamma S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad55e7c2f5310d57464dcb57b6f6ff3
https://doi.org/10.4049/jimmunol.140.9.3135
https://doi.org/10.4049/jimmunol.140.9.3135