Zobrazeno 1 - 10
of 484
pro vyhledávání: '"G Fenton"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3164-3174 (2024)
The study aimed to identify common differentially expressed lncRNAs from manually curated ulcerative colitis (UC) gene expression omnibus (GEO) datasets. Nine UC transcriptomic datasets of clearly annotated human colonic biopsies were included in the
Externí odkaz:
https://doaj.org/article/7dc862188221439e971bcfa9890c5533
Autor:
Wei Meng, Christopher G. Fenton, Kay-Martin Johnsen, Hagar Taman, Jon Florholmen, Ruth H. Paulssen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract DNA methylation has been implied to play a role in the immune dysfunction associated with inflammatory bowel disease (IBD) and the disease development of ulcerative colitis (UC). Changes of the DNA methylation and correlated gene expression
Externí odkaz:
https://doaj.org/article/bc54cd138aab4111b45ebe330b96abf6
Autor:
Alicia Villatoro, Vincent Cuminetti, Aurora Bernal, Carlos Torroja, Itziar Cossío, Alberto Benguría, Marc Ferré, Joanna Konieczny, Enrique Vázquez, Andrea Rubio, Peter Utnes, Almudena Tello, Xiaona You, Christopher G. Fenton, Ruth H. Paulssen, Jing Zhang, Fátima Sánchez-Cabo, Ana Dopazo, Anders Vik, Endre Anderssen, Andrés Hidalgo, Lorena Arranz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-28 (2023)
Abstract Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid leukemia (AML) patients and represents a prognos
Externí odkaz:
https://doaj.org/article/afa216c403e945989b02eb0db5160047
Publikováno v:
Non-coding RNA Research, Vol 7, Iss 1, Pp 40-47 (2022)
Background and aims: The study aimed to identify yet unknown and uncharacterized long non-coding RNAs (lncRNAs) in treatment-naïve ulcerative colitis (UC), and to define their possible roles in UC pathogenesis. For that purpose, accurate quantificat
Externí odkaz:
https://doaj.org/article/19e60fa45cc64d8fbf6af08d7cc7ed6e
Autor:
Alicia Villatoro, Vincent Cuminetti, Aurora Bernal, Carlos Torroja, Itziar Cossío, Alberto Benguría, Marc Ferré, Joanna Konieczny, Enrique Vázquez, Andrea Rubio, Peter Utnes, Almudena Tello, Xiaona You, Christopher G. Fenton, Ruth H. Paulssen, Jing Zhang, Fátima Sánchez-Cabo, Ana Dopazo, Anders Vik, Endre Anderssen, Andrés Hidalgo, Lorena Arranz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/eb990af88f664f3d92bb4534d48a9903
Autor:
C. G. Fenton, C. L. Doig, S. Fareed, A. Naylor, A. P. Morrell, O. Addison, C. Wehmeyer, C. D. Buckley, M. S. Cooper, G. G. Lavery, K. Raza, R. S. Hardy
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background Despite their efficacy in the treatment of chronic inflammation, the prolonged application of therapeutic glucocorticoids (GCs) is limited by significant systemic side effects including glucocorticoid-induced osteoporosis (GIOP).
Externí odkaz:
https://doaj.org/article/5c44e2a162a740648662dc940e7bc0af
Autor:
C. G. Fenton, J. M. Webster, C. S. Martin, S. Fareed, C. Wehmeyer, H. Mackie, R. Jones, A. P. Seabright, J. W. Lewis, Y. C. Lai, C. S. Goodyear, S. W Jones, M. S. Cooper, G. G. Lavery, R. Langen, K. Raza, R. S. Hardy
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background Patients with rheumatoid arthritis (RA) experience extra-articular manifestations including osteoporosis and muscle wasting, which closely associate with severity of disease. Whilst therapeutic glucocorticoids (GCs) reduce inflamm
Externí odkaz:
https://doaj.org/article/88f4fa171f8c489ca2601cae7a73bbe6
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248905 (2021)
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal cancer (CRC) risk. The aim of this study was to explore the relationship between transcriptomic and genome-wide DNA methylation profiles in a well-st
Externí odkaz:
https://doaj.org/article/239c27cef6e949078763540f25f25eda
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10500
Long non-coding RNAs (lncRNAs) have been shown to play a role in the pathogenesis of ulcerative colitis (UC). Although epigenetic processes such as DNA methylation and lncRNA expression are well studied in UC, the importance of the interplay between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::bf17860501e8a3515b2d316766fcadb3
Publikováno v:
Functional & Integrative Genomics. 23
Due to the lack of clinical, immunologic, genetic, and laboratory markers to predict remission in ulcerative colitis (UC) without relapse, there is no clear recommendation regarding withdrawal of therapy. Therefore, this study was to investigate if t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16bf24ead8d6896aa558109dedbe082
https://doi.org/10.1007/s10142-023-01099-9
https://doi.org/10.1007/s10142-023-01099-9