Zobrazeno 1 - 10
of 15
pro vyhledávání: '"G F Lockwood"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 24:249-254
Currently, the use of classical bioequivalence criteria is being called into question for certain classes of drugs such as bisphosphonates. These compounds typically possess a wide therapeutic index but may be characterized by low and variable absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454a0e9395bb0a42990f4b858a7ff03e
https://doi.org/10.1007/bf03190028
https://doi.org/10.1007/bf03190028
Autor:
P. A. Fox, J Rogers, G F Lockwood, Dennis Greenslade, K Lasher, H. Thysell, Dennis Lendrem, S. G. Woolfrey, J Hegbrant
Publikováno v:
Journal of Pharmacy and Pharmacology. 47:651-655
This study was designed to test a proposed dose modification for intravenous milrinone in congestive heart failure patients (CHF, NYHA I-II) with either moderate or severe renal impairment. All the patients were administered an intravenous loading do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed979862d7a8bb212ca46bd1e25817ab
https://doi.org/10.1111/j.2042-7158.1995.tb05853.x
https://doi.org/10.1111/j.2042-7158.1995.tb05853.x
Autor:
P M, LoRusso, B J, Foster, A, Wozniak, L K, Heilbrun, J I, McCormick, P E, Ruble, M A, Graham, J, Purvis, J, Rake, M, Drozd, G F, Lockwood, T H, Corbett
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
SR233377 is a novel thioxanthenone analogue that demonstrated solid tumor selectivity in vitro with activity confirmed in vivo against several murine tumors including those of colon, pancreas, and mammary origin. Its primary preclinical dose-limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e44301546982d7214898850eff7d52f2
https://pubmed.ncbi.nlm.nih.gov/10955788
https://pubmed.ncbi.nlm.nih.gov/10955788
Autor:
J B Houston, G F Lockwood
Publikováno v:
Journal of Pharmacy and Pharmacology. 34:777-781
The effect of cold stress and ether stress on mixed function oxidase activity in vivo has been studied using the aminopyrine-−14CO2 exhalation rate (CER) method. Cold stress following both acute and chronic exposure resulted in enhanced rate of dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77daba85df171f5315405e05b26f310e
https://doi.org/10.1111/j.2042-7158.1982.tb06224.x
https://doi.org/10.1111/j.2042-7158.1982.tb06224.x
Autor:
G. F. Lockwood, Rosemary R. Berardi, Martha L. Hyneck, John G. Wagner, E. Sakmar, Ira A. Cohen, J. J. Wells, U. A. Shukla
Publikováno v:
Biopharmaceutics & Drug Disposition. 5:169-176
A two-way crossover bioavailability study of two commercial cimetidine formaulations was performed on 24 healthy male volunteers. Drug was administered after an overnight fast and plasma samples were withdrawn periodically for 12 h. Urine was collect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dcbf87895fd3d707e408730b0e6646
https://doi.org/10.1002/bdd.2510050210
https://doi.org/10.1002/bdd.2510050210
Autor:
Robert G. Garrison, G. F. Lockwood
Publikováno v:
Mycopathologia et Mycologia Applicata. 35:377-388
The results of this study indicate thatHistoplasma capsulatum in its saprophytic form is able to utilize the major nitrogenous constituent of avian manure as a nitrogen source. In addition, the enzymes responsible for the pathway of uric acid degrada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f78f3a71eb698645f3e7df91ca1d78e
https://doi.org/10.1007/bf02050753
https://doi.org/10.1007/bf02050753
Autor:
John G. Wagner, G. F. Lockwood
Publikováno v:
Biopharmaceutics & Drug Disposition. 4:397-399
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b0946f210e69e7c7086aa5df81d986
https://doi.org/10.1002/bdd.2510040411
https://doi.org/10.1002/bdd.2510040411
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 9(5)
The usefulness of determining aminopyrine demethylation kinetics via monitoring of metabolite exhalation rats had been assessed. In rats receiving [N-dimethyl-14C]aminopyrine, a biexponential decline in the 14CO2 exhalation rate is apparent when moni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4270f8c36a87f73a3f2445bacba49dff
https://pubmed.ncbi.nlm.nih.gov/6117444
https://pubmed.ncbi.nlm.nih.gov/6117444
Autor:
G F, Lockwood, R L, Newman
Publikováno v:
Obstetrics and gynecology. 44(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3822346fda51010245c1548e226ed5b5
https://pubmed.ncbi.nlm.nih.gov/4608396
https://pubmed.ncbi.nlm.nih.gov/4608396
Autor:
J B Houston, G F Lockwood
Publikováno v:
The Journal of pharmacy and pharmacology. 31(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f21aa330d05584a7c307e5bde511a2
https://pubmed.ncbi.nlm.nih.gov/41916
https://pubmed.ncbi.nlm.nih.gov/41916