Zobrazeno 1 - 10
of 128
pro vyhledávání: '"G F, Vande Woude"'
Autor:
Lauren C. Harshman, Toni K. Choueiri, Michael B. Atkins, Marcella Callea, G F Vande Woude, Kathryn P. Gray, Laurence Albiges, Soumitro Pal, Rupal S. Bhatt, Aly-Khan A. Lalani, Mamta Gupta, David F. McDermott, Jean-Christophe Pignon, Sabina Signoretti
Publikováno v:
Oncotarget
In preclinical models, c-Met promotes survival of renal cancer cells through the regulation of programmed death-ligand 1 (PD-L1). However, this relationship in human clear cell renal cell carcinoma (ccRCC) is not well characterized. We evaluated c-Me
Autor:
F. H. Yang, B. Zhang, D. J. Zhou, L. Bie, M. W. Tom, D. C. Drummond, T. Nicolaides, S. Mueller, A. Banerjee, J. W. Park, M. D. Prados, D. C. James, N. Gupta, R. Hashizume, G. W. Strohbehn, J. Zhou, M. Fu, T. R. Patel, J. M. Piepmeier, W. M. Saltzman, Q. Xie, J. Johnson, R. Bradley, M. L. Ascierto, L. Kang, J. Koeman, F. M. Marincola, M. Briggs, K. Tanner, G. F. Vande Woude, S. Tanaka, L. K. Klofas, H. Wakimoto, D. R. Borger, A. J. Iafrate, T. T. Batchelor, A. S. Chi, A. B. Madhankumar, B. Slagle-Webb, E. Rizk, K. Harbaugh, J. R. Connor, G. Sarkar, G. L. Curran, R. B. Jenkins, K. Kurozumi, T. Ichikawa, M. Onishi, K. Fujii, J. Ishida, Y. Shimazu, I. Date, K. Ebsworth, M. J. Walters, L. S. Ertl, Y. Wang, R. D. Berahovich, P. Zhang, J. P. Powers, S.-C. Liu, R. Al Omran, T. J. Sullivan, J. C. Jaen, M. Brown, T. J. Schall, N. Yusuke, S. Shimizu, Y. Shishido-Hara, Y. Shiokawa, M. Nagane, J. Wang, K. Sai, F.-R. Chen, Z.-P. Chen, Z. Shi, J. Zhang, K. Zhang, L. Han, L. Chen, X. Qian, A. Zhang, G. Wang, Z. Jia, P. Pu, C. Kang, L.-Y. Kong, T. A. Doucette, S. D. Ferguson, J. Hachem, Y. Yang, J. Wei, W. Priebe, G. N. Fuller, W. Qiao, G. Rao, A. B. Heimberger, P.-Y. Chen, T. Ozawa, D. Drummond, R. Santos, J. D. Torre, C. Ng, E. L. Lepe, N. Butowski, M. Prados, K. Bankiewicz, C. D. James, Z. Cheng, Y. Gong, Y. Ma, S. Muller-Knapp, S. Knapp, E. Antonio Chiocca, B. Kaur, J. S. Yu, V. Judkowski, A. Bunying, J. Ji, Z. Li, J. Bender, C. Pinilla, V. Srinivasan, M. Dombovy-Johnson, E. Carson-Walter, K. Walter, Z. Xu, B. Popp, D. Schlesinger, L. Gray, J. Sheehan, S. T. Keir, H. S. Friedman, D. D. Bigner, C. Kut, B. Tyler, E. McVeigh, X. Li, D. Herzka, S. Grossman, J. L. Lasky, E. Panosyan, W. H. Meisen, J. Hardcastle, J. Wojton, E. Wohleb, C. Alvarez-Breckenridge, M. Nowicki, J. Godbout, S. Y. Lee, J. M. Sheehan, S. Yin, S. Kaluz, S. N. Devi, R. de Noronha, K. C. Nicolaou, E. G. Van Meir, J. E. Lachowicz, M. Demeule, C. Che, S. Tripathy, S. Jarvis, J.-C. Currie, A. Regina, T. Nguyen, J.-P. Castaigne, K. Zielinska-Chomej, C. Mohanty, K. Viktorsson, R. Lewensohn, J. J. Driscoll, S. Alsidawi, R. E. Warnick, O. Rixe, A. C. deCarvalho, S. Irtenkauf, L. Hasselbach, H. Xin, T. Mikkelsen, J. H. Sherman, A. Siu, O. Volotskova, M. Keidar, D. M. Gibo, P. Dickinson, J. Robertson, J. Rossmeisl, W. Debinski, S. Nair, R. Schmittling, D. Boczkowski, G. Archer, J. H. Sampson, D. A. Mitchell, I. S. Miller, S. Didier, D. W. Murray, M. Issaivanan, S. J. Coniglio, J. E. Segall, Y. Al-Abed, M. Symons, A. Fotovati, K. Hu, J. Triscott, J. Bacha, D. M. Brown, S. E. Dunn, D. J. Daniels, T. E. Peterson, A. B. Dietz, G. J. Knutson, I. F. Parney, R. J. Diaz, B. Golbourn, D. Picard, C. Smith, A. Huang, J. Rutka, N. Saito, J. Fu, J. Yao, S. Wang, D. Koul, W. K. A. Yung, Y. Yuan, E. P. Sulman, H. Colman, F. F. Lang, E. A. Slat, E. D. Herzog, J. B. Rubin, A. S. Carminucci, B. Amendolara, R. Leung, L. Lei, P. Canoll, J. N. Bruce, J. A. Wojton, Z. Chu, C.-H. Kwon, L. M. Chow, M. Palascak, R. Franco, T. Bourdeau, S. Thornton, X. Qi, G. J. Kitange, A. C. Mladek, D. Su, B. L. Carlson, M. A. Schroeder, J. L. Pokorny, K. K. Bakken, S. K. Gupta, P. A. Decker, W. Wu, J. N. Sarkaria, M. P. Oddou, A. Mollard, L. T. Call, H. Vakayalapati, S. L. Warner, S. Sharma, D. J. Bearss, T. C. Chen, H. Cho, W. Wang, F. M. Hofman, C. T. Flores, D. Snyder, L. Sanchez-Perez, C. Pham, H. Friedman, E. Woolf, M. G. Abdelwahab, G. Turner, M. C. Preul, A. Lynch, J. M. Rho, A. C. Scheck, L. Salphati, T. P. Heffron, B. Alicke, K. Barck, R. A. Carano, J. Cheong, J. Greve, L. B. Lee, M. Nishimura, J. Pang, E. G. Plise, H. B. Reslan, X. Zhang, S. G. GOuld, A. G. Olivero, H. S. Phillips, G. Zadeh, S. Jalali, D. Voce, Z. Wei, K. Shijun, K. Nikolai, W. Josh, C. Clayton, Y. Bakhtiar, R. Alkins, A. Burgess, M. Ganguly, W. Wels, K. Hynynen, Y. M. Li, H. Jun, V. Daniel, H. A. Walter, H. Nakashima, T. T. Nguyen, I. Shalkh, W. F. Goins, E. A. Chiocca, I. V. Pyko, M. Nakada, N. Furuyama, T. Lei, Y. Hayashi, K. Kawakami, T. Minamoto, A. S. Fedulau, J.-i. Hamada
Publikováno v:
Neuro-Oncology. 14:vi25-vi37
Ginsenoside Rg3 is a natural active ingredient that is extracted from Korean red ginseng root. It elevates the therapeutic effect of radiotherapy and chemotherapy, but previous studies found that the application of Rg3 is heavily limited by its low b
Publikováno v:
Oncogene
Summary CDK2-cyclin E triggers centrosome duplication, and nucleophosmin (NPM/B23) is found to be one of its targets. NPM/B23 phosphorylated by CDK2-cyclin E acquires a high binding affinity to Rho-associated kinase (ROCK II), and physically associat
Autor:
Shahriar Koochekpour, Nicholas S. Duesbery, Han-Mo Koo, James H. Resau, Stephen H. Leppla, Craig P. Webb, G F Vande Woude
Publikováno v:
Proceedings of the National Academy of Sciences. 98:4089-4094
Lethal factor is a protease, one component of Bacillus anthracis exotoxin, which cleaves many of the mitogen-activated protein kinase kinases (MEKs). Given the importance of MEK signaling in tumorigenesis, we assessed the effects of anthrax lethal to
Autor:
Nicholas S. Duesbery, G F Vande Woude
Publikováno v:
Journal of Applied Microbiology. 87:289-293
A search of the National Cancer Institute's Anti-Neoplastic Drug Screen for compounds with an inhibitory profile similar to that of the mitogen-activated protein kinase kinase (MAPKK) inhibitor PD098059 yielded anthrax lethal toxin. Anthrax lethal fa
Autor:
Kazuyasu Sakaguchi, M Fiscella, Shuren Shen, W E Mercer, H Zhang, S Fan, Patrick M. O'Connor, G F Vande Woude, Ettore Appella
Publikováno v:
Proceedings of the National Academy of Sciences. 94:6048-6053
Exposure of mammalian cells to ionizing radiation (IR) induces a complex array of cellular responses including cell cycle arrest and/or apoptosis. IR-induced G 1 arrest has been shown to depend on the presence of the tumor suppressor p53, which acts
Publikováno v:
Biology of Reproduction. 55:1261-1270
During meiotic maturation, numerous cytoplasmic and nuclear events take place that prepare the oocytes for fertilization. These changes are initiated by an increase in the activity of several kinases, most notably maturation-promoting factor, also ca
Autor:
Renping Zhou, K Fukasawa, G F Vande Woude, Taesaeng Choi, K Borror, Lino Tessarollo, James H. Resau
Publikováno v:
Proceedings of the National Academy of Sciences. 93:7032-7035
Mos is an upstream activator of mitogen-activated protein kinase (MAPK) and, in mouse oocytes, is responsible for metaphase II arrest. This activity has been likened to its function in Xenopus oocytes as a component of cytostatic factor. Thus, Mos-de
Autor:
G F Vande Woude, Kenji Fukasawa
Publikováno v:
Proceedings of the National Academy of Sciences. 92:3430-3434
High levels of mos protooncogene product are expressed during oocyte meiotic maturation and Mos has been implicated in formation of the spindle and spindle pole. Here, we show that in Swiss 3T3 cells with 4N DNA content, high levels of Mos lead to th