Systemic urocortin 2, but not urocortin 1 or stressin 1-A, suppresses feeding via CRF2 receptors without malaise and stress

Autor: E M, Fekete, Y, Zhao, A, Szücs, V, Sabino, P, Cottone, J, Rivier, W W, Vale, G F, Koob, E P, Zorrilla

Publikováno v: British journal of pharmacology. 164(8)

Infusion of corticotropin-releasing factor (CRF)/urocortin (Ucn) family peptides suppresses feeding in mice. We examined whether rats show peripheral CRF/Ucn-induced anorexia and determined its behavioural and pharmacological bases.Male Wistar rats (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8eacf7dccc807f3047f70fbee9d8aff3
https://pubmed.ncbi.nlm.nih.gov/21627635

Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats

Autor: M, Vallée, W, Shen, S C, Heinrichs, C F, Zorumski, D F, Covey, G F, Koob, R H, Purdy

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2001, 14 (12), pp.2003-2010. ⟨10.1046/j.0953-816x.2001.01817.x⟩
European Journal of Neuroscience, 2001, 14 (12), pp.2003-2010. ⟨10.1046/j.0953-816x.2001.01817.x⟩

International audience; Pregnenolone sulphate (PREGS) has generated interest as one of the most potent memory-enhancing neurosteroids to be examined in rodent learning studies, with particular importance in the ageing process. The mechanism by which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::67b401a0c4a1622bda1b67104ba50c31
https://hal.archives-ouvertes.fr/hal-02323909

Increased ethanol self-administration in delta-opioid receptor knockout mice

Autor: A J, Roberts, L H, Gold, I, Polis, J S, McDonald, D, Filliol, B L, Kieffer, G F, Koob

Publikováno v: Alcoholism, clinical and experimental research. 25(9)

The role of the delta-opioid receptor in ethanol drinking has remained unclear despite the use of traditional pharmacological and correlational approaches. The results of several studies suggest that pharmacological blockade of these receptors result

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0b8a6c0e7fdf22c52ba1a21e89491c7
https://pubmed.ncbi.nlm.nih.gov/11584142

Animal models of craving: a roundtable discussion

Autor: G F, Koob, F, Weiss, S T, Tiffany, W, Zieglgansberger, R, Spanagel

Publikováno v: Alcohol Research & Health

Five experts respected for their work in the development of animal models of alcohol craving offer their perspectives in a roundtable discussion format. The panel members discuss the various definitions and theories of alcohol craving and the benefit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ac252e9c858e0a726c77b1cfa4db389
https://pubmed.ncbi.nlm.nih.gov/10890819

Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects

Autor: S S, Watkins, L, Stinus, G F, Koob, A, Markou

Publikováno v: The Journal of pharmacology and experimental therapeutics. 292(3)

The negative affective aspects of nicotine withdrawal have been hypothesized to contribute to tobacco dependence. In the present studies in rats, brain stimulation reward thresholds, conditioned place aversions, and somatic signs of withdrawal were u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2ec742c67be678dea9421061ac2cd15e
https://pubmed.ncbi.nlm.nih.gov/10688623