Zobrazeno 1 - 10
of 40
pro vyhledávání: '"G F, Gibbons"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 3, Pp 469-481 (1997)
Cultured hepatocytes from rats fed a low fat, chow diet (LF) or diets rich in fish oil (FO, 20% v/w) or olive oil (OO, 20%, v/w) were used to determine how the intracellular metabolism and secretion of apolipoproteins (apo)B-100 and B-48 respond to i
Externí odkaz:
https://doaj.org/article/69a73f5922eb4e3e809d3656c9fc1458
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 10, Pp 1801-1808 (1994)
The human hepatoma cell line HepG2 in culture medium synthesized fatty acids de novo (144 +/- 9 nmol fatty acid/mg protein per 24 h) at a rate similar to that observed in freshly prepared rat hepatocytes (192 +/- 8 nmol/mg per 24 h) and in primary cu
Externí odkaz:
https://doaj.org/article/0f12fb8ba5d44f80b6e88c017e749fd9
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 12, Pp 1358-1367 (1984)
In rat hepatocytes freshly isolated from donor rats at different times of the day, the rates of lipogenesis (de novo fatty acid synthesis) varied with a diurnal periodicity. The maximal rate occurred approximately 5 hr after the end of the normal 8-h
Externí odkaz:
https://doaj.org/article/503f5be511f441fbbcb78f220f232293
Autor:
C R Pullinger, G F Gibbons
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 10, Pp 1321-1328 (1983)
The true rate of sterol synthesis in liver cells was determined by measurement of the weight of desmosterol produced over a given time period during incubations in the presence of triparanol. The simultaneous presence of tritiated water (3H2O) during
Externí odkaz:
https://doaj.org/article/e2b65c104a96480eb29932316201f18c
Publikováno v:
European Journal of Clinical Investigation. 28:720-729
Background Calcium antagonists lower plasma levels of lipoproteins and suppress hepatic very low-density lipoprotein (VLDL) secretion. Similar effects have been observed with the calcium ionophore A23187. We studied further the effect of calcium on V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8390c7babd9e5cd2a65b23317930e37
https://doi.org/10.1046/j.1365-2362.1998.00354.x
https://doi.org/10.1046/j.1365-2362.1998.00354.x
Publikováno v:
Scopus-Elsevier
In hepatocytes cultured in the presence of oleate (initial concn. 0.75 mM), the secretion of very-low-density lipoprotein (VLDL) triacylglycerol and, to a lesser extent, apoprotein B (apoB) increased with time, whereas there was a large decline in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2099e308ff9c77afa190efa8f06a6a4
https://doi.org/10.1042/bj2870749
https://doi.org/10.1042/bj2870749
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 7, Pp 1017-1027 (1992)
In primary cultures of rat hepatocytes, prostaglandin E2 and prostaglandin D2 (PGE2 and PGD2) inhibited the secretion of very low density lipoprotein (VLDL)-associated apoB, triacylglycerol, and cholesterol. These effects were concentration-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32967adbec3cb9446127e677205fa2c6
https://doi.org/10.1016/s0022-2275(20)41417-8
https://doi.org/10.1016/s0022-2275(20)41417-8
Autor:
G F Gibbons, D Wiggins
Publikováno v:
Biochemical Journal. 284:457-462
In hepatocyte cultures maintained in the absence of extracellular fatty acids, at least 70% of the secreted very-low-density lipoprotein (VLDL) triacylglycerol was derived via lipolysis of intracellular triacylglycerol. This proportion was unchanged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce43551f8ebcd370188845941420351
https://doi.org/10.1042/bj2840457
https://doi.org/10.1042/bj2840457
Autor:
G F Gibbons, F J Burnham
Publikováno v:
Biochemical Journal. 275:87-92
The mass of very-low-density-lipoproteins (VLDL) triacylglycerol secreted from isolated hepatocytes was dependent on the nutritional state of the donor rats, and declined in the order sucrose-fed greater than chow-fed greater than polyunsaturated-fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613861a8601dd45a101b5f1fdb3c5324
https://doi.org/10.1042/bj2750087
https://doi.org/10.1042/bj2750087
Publikováno v:
Biochemical Journal. 271:761-766
The distribution of newly synthesized and exogenous fatty acids and of newly synthesized cholesterol between cellular and very-low-density lipoprotein (VLDL) lipids was studied in hepatocytes derived from animals fed on a normal diet or on diets supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb309c4e85eef778bf195f627712368a
https://doi.org/10.1042/bj2710761
https://doi.org/10.1042/bj2710761