Zobrazeno 1 - 10
of 143
pro vyhledávání: '"G F, Cooper"'
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background High-throughput RNA sequencing (RNA-seq) has evolved as an important analytical tool in molecular biology. Although the utility and importance of this technique have grown, uncertainties regarding the proper analysis of RNA-seq da
Externí odkaz:
https://doaj.org/article/5211d3632bae457abe93c3e8b6f179bd
Autor:
G. F. Cooper, E. C. Inglis
Publikováno v:
Frontiers in Earth Science, Vol 9 (2022)
Lavas produced at subduction zones represent the integration of both source heterogeneity and an array of crustal processes, such as: differentiation; mixing; homogenisation; assimilation. Therefore, unravelling the relative contribution of the sub-a
Externí odkaz:
https://doaj.org/article/99fa8359f4cf48e0bc6bb4c5cb0130dd
Publikováno v:
Frontiers in Earth Science, Vol 9 (2021)
The chemical and isotopic compositions of volcanic arc lavas often show evidence for involvement of a sedimentary component during magma genesis. Determining where this sedimentary component is added to arc magmas is of vital importance for constrain
Externí odkaz:
https://doaj.org/article/9eb93f833e1c4962b68bcc62e6fa2775
Autor:
Mohamed Chaabane, Kalina Andreeva, Jae Yeon Hwang, Tae Lim Kook, Juw Won Park, Nigel G F Cooper
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008338 (2020)
Over the past two decades, researchers have discovered a special form of alternative splicing that produces a circular form of RNA. Although these circular RNAs (circRNAs) have garnered considerable attention in the scientific community for their bio
Externí odkaz:
https://doaj.org/article/9891f01e45f1491d8bbe8f503d5afcdd
Autor:
Xiaohong Li, Eric C Rouchka, Guy N Brock, Jun Yan, Timothy E O'Toole, David A Tieri, Nigel G F Cooper
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201813 (2018)
Breast cancer (BC) is increasing in incidence and resistance to treatment worldwide. The challenges in limited therapeutic options and poor survival outcomes in BC subtypes persist because of its molecular heterogeneity and resistance to standard end
Externí odkaz:
https://doaj.org/article/97566553d6bd4255b00c581fde6a0e99
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187426 (2017)
The goal of this study is to develop a model that explains the relationship between microRNAs, transcription factors, and their co-target genes. This relationship was previously reported in gene regulatory loops associated with 24 hour (24h) and 7 da
Externí odkaz:
https://doaj.org/article/5893ce240a0443c2adb115b717c810fe
Autor:
Xiaohong Li, Guy N Brock, Eric C Rouchka, Nigel G F Cooper, Dongfeng Wu, Timothy E O'Toole, Ryan S Gill, Abdallah M Eteleeb, Liz O'Brien, Shesh N Rai
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176185 (2017)
Normalization is an essential step with considerable impact on high-throughput RNA sequencing (RNA-seq) data analysis. Although there are numerous methods for read count normalization, it remains a challenge to choose an optimal method due to multipl
Externí odkaz:
https://doaj.org/article/a8a395924fac4d30ad6a7991f554b336
Publikováno v:
BioMedInformatics
Volume 1
Issue 2
Pages 4-63
Volume 1
Issue 2
Pages 4-63
Sample size calculation for adequate power analysis is critical in optimizing RNA-seq experimental design. However, the complexity increases for directly estimating sample size when taking into consideration confounding covariates. Although a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f82e45e2125afef63e655b0030cd622
https://doi.org/10.3390/biomedinformatics1020004
https://doi.org/10.3390/biomedinformatics1020004
Autor:
Aruni Bhatnagar, Daniel W. Riggs, Ray Yeager, Xiaohong Li, Nigel G. F. Cooper, David Hoetker, Shahid P Baba, Timothy E. O'Toole, Pawel Lorkiewicz
Publikováno v:
Inhal Toxicol
OBJECTIVE: The inhalation of air-borne toxicants is associated with adverse health outcomes which can be somewhat mitigated by enhancing endogenous anti-oxidant capacity. Carnosine is a naturally occurring dipeptide (β-alanine-L-histidine), present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1794eaccf2a588a738144c9a8012a1ba
https://doi.org/10.1080/08958378.2020.1845257
https://doi.org/10.1080/08958378.2020.1845257
Autor:
Kalina Andreeva, Nigel G. F. Cooper
Publikováno v:
International Journal of Genomics, Vol 2014 (2014)
The health and function of the visual system rely on a collaborative interaction between diverse classes of molecular regulators. One of these classes consists of transcription factors, which are known to bind to DNA and control the transcription act
Externí odkaz:
https://doaj.org/article/3e35e2786f1a4dccbd98d8998381a22f