Zobrazeno 1 - 10
of 44
pro vyhledávání: '"G Engelke"'
Autor:
Benjamin A Y Cher, Eric A Wilson, Alexa M Pinsky, Ryan F Townshend, Ann V Wolski, Michael Broderick, Allison M Milen, Audrey Lau, Amrit Singh, Sandro K Cinti, Carl G Engelke, Anjan K Saha
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 11, p e28105 (2021)
BackgroundDuring the initial months of the COVID-19 pandemic, rapidly rising disease prevalence in the United States created a demand for patient-facing information exchanges that addressed questions and concerns about the disease. One approach to ma
Externí odkaz:
https://doaj.org/article/5558bfd039a14e0a9241bf1c7b4a3671
Autor:
Yajing Liu, Sahezeel Awadia, Amy Delaney, Merna Sitto, Carl G. Engelke, Heli Patel, Andrew Calcaterra, Sylvia Zelenka-Wang, Hojin Lee, Joseph Contessa, Nouri Neamati, Mats Ljungman, Theodore S. Lawrence, Meredith A. Morgan, Alnawaz Rehemtulla
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100834- (2020)
The Unfolded Protein Response (UPR) plays a key role in the adaptive response to loss of protein homeostasis within the endoplasmic reticulum (ER). The UPR has an adaptive function in protein homeostasis, however, sustained activation of the UPR due
Externí odkaz:
https://doaj.org/article/8565fd736ec64fb4919739945b14f89d
Autor:
Meredith A. Morgan, Theodore S. Lawrence, Christine E. Canman, Daniel R. Wahl, Daria Tanska, Qiang Zhang, Sheryl A. Flanagan, Joshua Parsels, Carl G. Engelke, Leslie A. Parsels
PARP inhibitor monotherapy (olaparib) was recently FDA approved for the treatment of BRCA1/2-mutant, homologous recombination (HR) repair-deficient pancreatic cancer. Most pancreatic cancers, however, are HR proficient and thus resistant to PARP inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c065c0fdfb526bd02e24a6cc4c4b70c
https://doi.org/10.1158/1535-7163.c.6542746.v1
https://doi.org/10.1158/1535-7163.c.6542746.v1
Autor:
Meredith A. Morgan, Theodore S. Lawrence, Christine E. Canman, Daniel R. Wahl, Daria Tanska, Qiang Zhang, Sheryl A. Flanagan, Joshua Parsels, Carl G. Engelke, Leslie A. Parsels
Suppl. Figs. 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603db91bb92004b40d6d714342045895
https://doi.org/10.1158/1535-7163.22520725.v1
https://doi.org/10.1158/1535-7163.22520725.v1
Autor:
Meredith A. Morgan, Jonathan Maybaum, Theodore S. Lawrence, Joel K. Greenson, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Dongping Wei, Daria M. Tanska, Jordan R. Robertson, David Karnak, Qiang Zhang, Yushen Qian, Leslie A. Parsels, Carl G. Engelke
PDF file, 126K, MK8776 treatment causes persistent gammaH2AX expression in response to gemcitabine/radiation in MiaPaCa-2 but not Capan-1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d119884b9a519379893e67c008240f8
https://doi.org/10.1158/1078-0432.22446759
https://doi.org/10.1158/1078-0432.22446759
Autor:
Meredith A. Morgan, Jonathan Maybaum, Theodore S. Lawrence, Joel K. Greenson, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Dongping Wei, Daria M. Tanska, Jordan R. Robertson, David Karnak, Qiang Zhang, Yushen Qian, Leslie A. Parsels, Carl G. Engelke
PDF file, 340K, MK8776 abrogates the G2 checkpoint in response to gemcitabine/radiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d09e2a57cc8b96ca621681be7548f60
https://doi.org/10.1158/1078-0432.22446762
https://doi.org/10.1158/1078-0432.22446762
Autor:
Meredith A. Morgan, Theodore S. Lawrence, Jonathan Maybaum, Lili Zhao, Mary A. Davis, Katherine B. Marsh, Jordan R. Robertson, Dongping Wei, Tasneem Kausar, Leslie A. Parsels, Carl G. Engelke, David Karnak
Supplementary Figure 1. The effects of AZD1775 and olaparib on the radiation-induced G2 checkpoint; S2: Sub-G1 DNA content following AZD1775, olaparib, and radiation treatments; S3: Weight loss associated with combined treatment with AZD1775, olapari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691df006b1bc5963ff72eb89209951cc
https://doi.org/10.1158/1078-0432.22461614.v1
https://doi.org/10.1158/1078-0432.22461614.v1
Autor:
Meredith A. Morgan, Jonathan Maybaum, Theodore S. Lawrence, Joel K. Greenson, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Dongping Wei, Daria M. Tanska, Jordan R. Robertson, David Karnak, Qiang Zhang, Yushen Qian, Leslie A. Parsels, Carl G. Engelke
PDF file, 78K, Summary of radiosensitization by MK8776.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c571c6618b15ab5b8bccfbd085fb060
https://doi.org/10.1158/1078-0432.22446744.v1
https://doi.org/10.1158/1078-0432.22446744.v1
Autor:
Meredith A. Morgan, Jonathan Maybaum, Theodore S. Lawrence, Joel K. Greenson, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Dongping Wei, Daria M. Tanska, Jordan R. Robertson, David Karnak, Qiang Zhang, Yushen Qian, Leslie A. Parsels, Carl G. Engelke
PDF file, 297K, Phosphorylated Chk1 (S345) in MiaPaCa-2 xenograft slices.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465c1a282bbef4ddcdfa6844defe7073
https://doi.org/10.1158/1078-0432.22446747.v1
https://doi.org/10.1158/1078-0432.22446747.v1
Autor:
Meredith A. Morgan, Jonathan Maybaum, Theodore S. Lawrence, Joel K. Greenson, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Dongping Wei, Daria M. Tanska, Jordan R. Robertson, David Karnak, Qiang Zhang, Yushen Qian, Leslie A. Parsels, Carl G. Engelke
PDF file, 85K, Pancreatic cancer cell survival in response to increasing concentrations of MK8776.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c01e17f942d3c38096e1377557fe2c
https://doi.org/10.1158/1078-0432.22446765.v1
https://doi.org/10.1158/1078-0432.22446765.v1