Zobrazeno 1 - 7
of 7
pro vyhledávání: '"G E Zurenko"'
Publikováno v:
Current Opinion in Pharmacology. 1:470-476
The oxazolidinones represent the first truly new class of antibacterial agents to reach the marketplace in several decades. They have a unique mechanism of action involving inhibition of the initiation step of protein synthesis and are not cross-resi
Autor:
Christine M Sanfilippo, D. L. Shinabarger, G. E. Zurenko, Christine K. Hesje, T.W. Morris, W. Haas
Publikováno v:
Journal of chemotherapy (Florence, Italy). 23(2)
This study examined the susceptibility of a variety of wild-type strains and efflux pump mutants to besifloxacin and the comparator agents sparfloxacin, ciprofloxacin, norfloxacin, moxifloxacin, tetracycline, and ethidium bromide. Organisms tested in
Autor:
M R, Barbachyn, S J, Brickner, R C, Gadwood, S A, Garmon, K C, Grega, D K, Hutchinson, K, Munesada, R J, Reischer, M, Taniguchi, L M, Thomasco, D S, Toops, H, Yamada, C W, Ford, G E, Zurenko
Publikováno v:
Advances in experimental medicine and biology. 456
Publikováno v:
Journal of clinical microbiology. 28(10)
Endoscopic, histologic, and microbiologic evaluations of 21 cynomolgus and 34 rhesus monkeys for naturally occurring Helicobacter pylori infection were done. H. pylori was never isolated from any cynomolgus monkey, but was found in 12 rhesus monkeys.
Publikováno v:
Journal of medicinal chemistry. 27(9)
An unusual acid-mediated rearrangement of o-nitrostyrene oxide afforded 1-(hydroxymethyl)-2,1-benzisoxazol-3(1H)-one which exhibited broad-spectrum antimicrobial and cytotoxic activity. A number of analogues were prepared by employing a modified zinc
Publikováno v:
Drugs under experimental and clinical research. 14(6)
Trospectomycin (TSP; U-63366F) is a novel spectinomycin (SP) analogue with broad-spectrum antibacterial activity. The in vitro activity of the analogue was compared to that of SP against approximately 400 bacterial isolates. The in vivo activity of t
Publikováno v:
Journal of medicinal chemistry. 27(2)
The preparation of a series of analogues of clindamycin is described in which the naturally occurring five-membered cyclic amino acid amide portion of the molecule is replaced by a four-, six-, or seven-membered cyclic amino acid amide. The most inte