Zobrazeno 1 - 10
of 26
pro vyhledávání: '"G E Rovati"'
Autor:
Christian Pinna, Paolo Ciana, Electra Brunialti, G. E. Rovati, Giuseppe Battaglia, Massimo Locati, Chiara Sfogliarini, Elisabetta Vegeto, Giovanna Pepe, Adriana Maggi, Loris Rizzello, Federica Mornata
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Biomedicine & Pharmacotherapy, Vol 144, Iss, Pp 112274-(2021)
Biomedicine & Pharmacotherapy
Universidad de Barcelona
Biomedicine & Pharmacotherapy, Vol 144, Iss, Pp 112274-(2021)
Biomedicine & Pharmacotherapy
Sex differences in immune-mediated diseases are linked to the activity of estrogens on innate immunity cells, including macrophages. Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in estrogen receptor-alpha (ERα)-dependent br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c994910ef146d1fc8be5adba855c1928
https://pubmed.ncbi.nlm.nih.gov/34653752
https://pubmed.ncbi.nlm.nih.gov/34653752
Autor:
Fabio Stellari, Patrizia Risé, Thierry Durand, Annalisa Trenti, Angelo Sala, Carola Buccellati, Chiara Bolego, Dayaker Gandrath, G. E. Rovati, Laurence Balas
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (21), pp.9961-9975. ⟨10.1021/acs.jmedchem.9b01463⟩
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (21), pp.9961-9975. ⟨10.1021/acs.jmedchem.9b01463⟩
International audience; Protectin D1 [neuroprotectin D1 (NPD1), PD1] has been proposed to play a key role in the resolution of inflammation. Aside from its ω-monohydroxylated metabolite, little has been reported on its metabolic fate. Upon NPD1 incu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ebe0611238fa4f44d0bb8529f4de40
https://pubmed.ncbi.nlm.nih.gov/31626541
https://pubmed.ncbi.nlm.nih.gov/31626541
Autor:
Emanuele Borroni, Ivan Brivio, Antonio Di Gennaro, Valérie Capra, Chiara Carnini, Marco Fiumicelli, Silvia Carnevali, Paolo Mangano, Carola Buccellati, Maria Rosa Accomazzo, Angelo Sala, G. E. Rovati
Publikováno v:
Prostaglandins & Other Lipid Mediators. 120:115-125
We evaluated the autocrine activities of cysteinyl leukotrienes (cysteinyl-LTs) in HUVEC and studied the signaling and the pharmacological profile of the CysLT2 receptor (CysLT2R) expressed by ECs, finally assessing the role of the CysLT2R in permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bca7dcd07042adcd514a224620844e7
https://doi.org/10.1016/j.prostaglandins.2015.03.007
https://doi.org/10.1016/j.prostaglandins.2015.03.007
Autor:
G. E. Rovati, Valérie Capra
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 12(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe428788ad6fa581833289a163e6085c
https://pubmed.ncbi.nlm.nih.gov/24612435
https://pubmed.ncbi.nlm.nih.gov/24612435
Autor:
M. Hoxha, V. Capra, C. Buccellati, A. Sala, C. Cena, R. Fruttero, M. Bertinaria, G. E. Rovati
Today COXIBs are used in the treatment of arthritis and many other painful conditions in selected patients with high gastrointestinal risk and low cardiovascular (CV) risk. Previously, we have identified an unexpected mechanism of action of a traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9ccfd827818ed082cc7126f88005fe
http://hdl.handle.net/2318/1523595
http://hdl.handle.net/2318/1523595
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 14:3-19
This review describes the aspects of leukotriene (LT) pharmacology and biology that are relevant to their important role in asthma. The biosynthesis and metabolism, including transcellular metabolism, of LTB4 and the cysteinyl-LTs (i.e. LTC4, LTD4 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a41b7a08a4eec00a4e270cecc74577
https://doi.org/10.1006/pupt.2000.0262
https://doi.org/10.1006/pupt.2000.0262
Autor:
Nicosia S, G. E. Rovati
Publikováno v:
Trends in Pharmacological Sciences. 15:140-144
It is very common in practice to find that some concentration-response curves are ‘bell shaped', and this phenomenon also applies to partial agonist curves. On the basis of these considerations, a mathematical model has been developed for the inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37b0378939e3604cc3e7cc8f6772d9b
https://doi.org/10.1016/0165-6147(94)90073-6
https://doi.org/10.1016/0165-6147(94)90073-6
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 38(5)
Montelukast is a potent cysteinyl leukotriene-1 receptor antagonist possessing some anti-inflammatory effects although the molecular mechanism of these anti-inflammatory effects is unknown. In this study, we aimed to investigate the effect of montelu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdd9938c92353eb95915f25b5905b08
https://pubmed.ncbi.nlm.nih.gov/18325031
https://pubmed.ncbi.nlm.nih.gov/18325031
Autor:
E, Selg, C, Buccellati, M, Andersson, G E, Rovati, M, Ezinga, A, Sala, A-K, Larsson, M, Ambrosio, E, Ambrosio, L, Låstbom, V, Capra, B, Dahlén, A, Ryrfeldt, G C, Folco, S-E, Dahlén
Publikováno v:
British journal of pharmacology. 152(8)
Non-steroidal anti-inflammatory drugs (NSAIDs) are analgesic and anti-inflammatory by virtue of inhibition of the cyclooxygenase (COX) reaction that initiates biosynthesis of prostaglandins. Findings in a pulmonary pharmacology project gave rise to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d5b7edb9fe24c19e89076109031ef26
https://pubmed.ncbi.nlm.nih.gov/17965743
https://pubmed.ncbi.nlm.nih.gov/17965743
Publikováno v:
Molecular pharmacology. 57(6)
We report the identification of a novel pharmacological profile for the leukotriene (LT)C(4) binding site we previously identified in human lung parenchyma (HLP). We used a series of classic cysteinyl-LT (CysLT)(1) receptor antagonists belonging to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2a3206afc658c505a676748eeeba04c
https://pubmed.ncbi.nlm.nih.gov/10825389
https://pubmed.ncbi.nlm.nih.gov/10825389