Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G E Hancock"'
Autor:
S M, van Schaik, N, Obot, G, Enhorning, K, Hintz, K, Gross, G E, Hancock, A M, Stack, R C, Welliver
Publikováno v:
Journal of medical virology. 62(2)
Immunologic mechanisms are thought to contribute to the pathogenesis of respiratory syncytial virus (RSV) bronchiolitis in humans. RSV-infected BALB/c mice exhibit tachypnea and signs of outflow obstruction, similar to symptoms in humans. Interferon
Autor:
C. K. Job, Kendall A. Smith, J Barker, Gilla Kaplan, P W Roche, R A Burkhardt, W J Britton, W J Theuvenet, A Molloy, G E Hancock
Publikováno v:
The Journal of Experimental Medicine
14 patients with lepromatous leprosy received twice daily injections of 10 micrograms recombinant interleukin 2 (rIL-2), by the intradermal route, in the skin of the back for 8 d (total dose, 160 micrograms). Lymphokine administration was accomplishe
Autor:
M. Becx‐Bleumink, P. J. Converse, Rolf Kiessling, M. Dietz, G E Hancock, Saba Work Teklemariam, T. H. M. Ottenhoff, Gilla Kaplan, Assefa Wondimu, Zanvil A. Cohn
Publikováno v:
Scandinavian journal of immunology. 32(2)
Thirty-one patients with lepromatous leprosy received recombinant interleukin 2 (IL-2) intradermally in doses ranging from 10 to 30 micrograms. Before injection and at time intervals of 2-21 days thereafter, samples of peripheral blood mononuclear ce
Publikováno v:
Infection and Immunity. 53:26-31
We investigated natural resistance in mice to Yersinia enterocolitica, an enteric bacterial pathogen of humans, with a view to determine host genetic factors that are important in resistance. Most mouse strains studied (C3H/HeN, BALB/c, BALB.B, DBA/2
Publikováno v:
The Journal of Experimental Medicine
We have examined an in vitro system in which PBMC from purified protein derivative (PPD)-sensitized patients generate CTL after in vitro activation with antigen. These cells selectively destroy mycobacterial antigen PPD-pulsed monocyte targets. These
Autor:
T. H. M. Ottenhoff, P Converse, M. Dietz, Giulia Sheftel, M. Becx‐Bleumink, Gilla Kaplan, S Teklemariam, G E Hancock, C. K. Job, R Kiessling
Publikováno v:
The Journal of Experimental Medicine
Human rIL-2 (10-30 micrograms) was injected intradermally into the skin of patients with lepromatous leprosy with high bacillary loads. All patients responded to the lymphokine with local areas of induration that peaked at 24 h and persisted for 4-7
Publikováno v:
The Journal of Experimental Medicine
We describe a bioassay that allows the in vitro investigation of the stimulatory and suppressive factors derived from immune cells in short-term cultures of human keratinocytes. In agreement with other assays, epidermal growth factor is not mitogenic
Autor:
G E Hancock, J F Jones
Publikováno v:
Infection and immunity. 42(2)
By using mice with naturally occurring defects, we have shown that an intact macrophage system is crucial to survival with the pathogenic protozoan Trypanosoma rhodesiense, since a defect in these cells decreased survival by half. Deficiencies in nat
Publikováno v:
Infection and Immunity. 56:532-533
By using recombinant inbred mice derived from strains genetically resistant or susceptible to Yersinia enterocolitica, we demonstrated a tentative linkage of resistance with the Es-1 locus on murine chromosome 8. No correlation with resistance and ge