Zobrazeno 1 - 10 of 10 pro vyhledávání: '"G E, Tranter"'
1
Characterisation of the solution conformation of a cyclic RGD peptide analogue by NMR spectroscopy allied with a genetic algorithm approach and constrained molecular dynamics
Autor: C. J. Harris, C. Heide, R. C. Glen, P. M. Doyle, G. E. Tranter, P. N. Sanderson, B. D. Hudson, A. W. R. Payne
Publikováno v: International Journal of Peptide and Protein Research. 43:588-596
The solution conformation of a cyclic RGD peptide analogue, cyclo-(S,S)-2-merrcaptobenzoate-arginine-glycine-aspartate -2-mercaptoanilide, has been determined via two independent approaches for the searching of conformational space and identification
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2621378ce54f53a81a7511727c8a6f
https://doi.org/10.1111/j.1399-3011.1994.tb00561.x
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2
Temperature denaturation and aggregation of a multi-domain protein (IgG1) investigated with an array of complementary biophysical methods
Autor: T Garfagnini, G E Tranter, S J P Gnaniah, Eleonora Cerasoli, Jascindra Ravi, D le Pevelen
Publikováno v: Analytical and bioanalytical chemistry. 406(26)
Proteins are used as drugs against different pathologies because of their potential specificity of action with fewer side effects. However, their production and successful storage imposes a greater challenge compared to small molecule drugs. Though t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df60326aa57845680fee40adcfb980d7
https://pubmed.ncbi.nlm.nih.gov/24994667
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4
NMR and QSAR studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. I: design, synthesis and degradation rate measurement
Autor: S J, Vanderhoeven, J C, Lindon, J, Troke, G E, Tranter, I D, Wilson, J K, Nicholson
Publikováno v: Xenobiotica; the fate of foreign compounds in biological systems. 34(1)
1. The products arising from intramolecular acyl migration reactions of drug ester glucuronides are reactive towards cellular proteins and can potentially cause toxic side-effects. The relationship between molecular structure and the degradation rate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10f006119f1ad8a83c4ea0775bda8139
https://pubmed.ncbi.nlm.nih.gov/15729774
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6
Biomolecular Handedness and the Weak Interaction
Autor: A. J. MacDermott, G. E. Tranter
Publikováno v: Symmetries in Science IV ISBN: 9781461278849
Most biomolecules exist in two enantiomeric or mirror-image forms, but only one of these forms is used naturally in terrestrial biochemistry. This broken symmetry is now believed to be a feature of fundamental physics — a result of symmetry-breakin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e37e353c3836df6c1bc77bb9db69c9f
https://doi.org/10.1007/978-1-4613-0597-2_5
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7
Electroweak Bioenantioselection
Autor: A. J. MacDermott, G. E. Tranter
Publikováno v: Croatica Chemica Acta
Volume 62
Issue 2A
This paper reviews evidence for the view that biomolecular chirality was determined not by chance but by the electroweak interaction. Other influences (such as the Earth's magnetic and gravitational fields, or circularly polarized light) are either f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::596b5fe7efdd52c91f3bf0d970555d78
https://hrcak.srce.hr/175391
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9
Parity-violating energy differences of chiral minerals and the origin of biomolecular homochirality
Autor: G. E. Tranter
Publikováno v: Nature. 318:172-173
The biochemistry of terrestrial organisms is based on chiral (handed) molecules, with one of the two possible series of enantiomers (mirror-image isomers) being predominant. Specifically, terrestrial biochemistry is homochirally supported by L-α-ami
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b4e888f17658742f081ca1d8233e894
https://doi.org/10.1038/318172a0
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10
Preferential stabilization of the D-sugar series by the parity-violating weak interactions
Autor: G. E. Tranter
Publikováno v: Journal of the Chemical Society, Chemical Communications. :60
Hydrated D-glyceraldehyde is stabilized relative to its corresponding L-enantiomer by the parity-violating weak interactions.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67e6d9be914e413f1d7b5bd64e632d92
https://doi.org/10.1039/c39860000060
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