Zobrazeno 1 - 10
of 55
pro vyhledávání: '"G E, Sonenshein"'
Publikováno v:
The Journal of Immunology. 163:6530-6535
Engagement of the B cell receptor of WEHI 231 immature B cells leads sequentially to a drop in c-Myc, to induction of the cyclin-dependent kinase inhibitor p27Kip1, and finally to apoptosis. Recently we demonstrated that the drop in c-Myc expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb220fc79441462fa8eaa16f08274f97
https://doi.org/10.4049/jimmunol.163.12.6530
https://doi.org/10.4049/jimmunol.163.12.6530
Autor:
G E Sonenshein
Publikováno v:
The Journal of Immunology. 158:1994-1997
Whereas overexpression of the c-myc gene was found to promote apoptosis in fibroblasts, myeloid, and T cells, physiologic cell death of immature B cell lymphomas correlated with a drop in c-myc expression. Here, the author reviews recent evidence dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0beee9492958f40f46ff3dd5617fdf1
https://doi.org/10.4049/jimmunol.158.5.1994
https://doi.org/10.4049/jimmunol.158.5.1994
Publikováno v:
The Journal of Immunology. 157:81-86
Engagement of surface IgM (sIgM) on WEHI 231 murine B lymphoma cells leads to abortive activation and apoptosis, suggesting that this cell line may represent a model for tolerance. Loss of viability in these cells is preceded by an early increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4333b96fac455537b80536d5ee6be880
https://doi.org/10.4049/jimmunol.157.1.81
https://doi.org/10.4049/jimmunol.157.1.81
Publikováno v:
The Journal of Immunology. 145:732-736
The binding of ligand to surface IgR results in the initial activation of B cells. As shown by experiments in which B cells are polyclonally stimulated with anti-Ig antibody, this includes an early increase in c-myc gene expression. In our study a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9100492738123d6e10205a47ea8bd5b2
https://doi.org/10.4049/jimmunol.145.2.732
https://doi.org/10.4049/jimmunol.145.2.732
Autor:
E, Landesman-Bollag, D H, Song, R, Romieu-Mourez, D J, Sussman, R D, Cardiff, G E, Sonenshein, D C, Seldin
Publikováno v:
Molecular and cellular biochemistry. 227(1-2)
Breast cancer is a major cause of cancer death in women, and the genetic abnormalities leading to the common sporadic forms of the disease are still under active investigation. CK2 has been reported to be upregulated in human breast cancer, which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::581d46d8d9663ef1db7df9f0ef641fd0
https://pubmed.ncbi.nlm.nih.gov/11827167
https://pubmed.ncbi.nlm.nih.gov/11827167
Autor:
R, Romieu-Mourez, E, Landesman-Bollag, D C, Seldin, A M, Traish, F, Mercurio, G E, Sonenshein
Publikováno v:
Cancer research. 61(9)
Nuclear factor-kappaB (NF-kappaB)/Rel transcription factors regulate genes that control cell proliferation, survival, and transformation. In normal breast epithelial cells, NF-kappaB/Rel proteins are mainly sequestered in the cytoplasm bound to one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c71ed17f55179ba166de776e26dd44c6
https://pubmed.ncbi.nlm.nih.gov/11325857
https://pubmed.ncbi.nlm.nih.gov/11325857
Publikováno v:
Endocrinology. 142(1)
Dependence of murine pro-B Ba/F3 cells on interleukin-3 can be substituted by GH when cells are stably transfected with the GH receptor (GHR) complementary DNA. Recently, we demonstrated that Ba/F3 cells produce GH, which is responsible for the survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1a2903e137c635985edbf72b884919b
https://pubmed.ncbi.nlm.nih.gov/11145577
https://pubmed.ncbi.nlm.nih.gov/11145577
Autor:
A F, Trombino, R I, Near, R A, Matulka, S, Yang, L J, Hafer, P A, Toselli, D W, Kim, A E, Rogers, G E, Sonenshein, D H, Sherr
Publikováno v:
Breast cancer research and treatment. 63(2)
Exposure to ubiquitous environmental chemicals, such as polycyclic aromatic hydrocarbons (PAH), may contribute to human breast cancer. In animals, PAH induce tumors in part by activating the aryl hydrocarbon receptor (AhR)/transcription factor. Histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f97a410ef8f25cfb4372ba13c09456f3
https://pubmed.ncbi.nlm.nih.gov/11097088
https://pubmed.ncbi.nlm.nih.gov/11097088
Publikováno v:
Journal of cellular biochemistry. 80(1)
Vascular smooth muscle cells (SMCs), the major cellular constituent of the medial layer of an artery, synthesize the majority of connective tissue proteins, including fibrillar collagen types I, III, and V/XI. Proper collagen synthesis and deposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd599a77ec8eb90a68fd3b1bbe7f86c1
https://pubmed.ncbi.nlm.nih.gov/11029762
https://pubmed.ncbi.nlm.nih.gov/11029762
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 10(8)
Nuclear factor (NF)-kappaB/Rel transcription factors normally exist in non-B cells, such as epithelial cells, in inactive forms sequestered in the cytoplasm with specific inhibitory proteins, termed IkappaBs. Recently, however, we discovered that bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e14074991ad3fb1210c52b6f4194ab64
https://pubmed.ncbi.nlm.nih.gov/10470853
https://pubmed.ncbi.nlm.nih.gov/10470853