Zobrazeno 1 - 10
of 20
pro vyhledávání: '"G E, Dukes"'
Publikováno v:
British journal of pharmacology. 167(4)
Delayed gastric emptying is poorly managed. Motilin agonists are potential treatments but inadequate understanding into how enteric nerve functions are stimulated compromises drug/dose selection. Resolution is hampered by extreme species dependency s
Publikováno v:
Alimentary pharmacologytherapeutics. 32(6)
Anxiety, depression and nongastrointestinal symptoms are often prominent in irritable bowel syndrome (IBS), but their relative value in patient management has not been quantitatively assessed. We modified the Patient Health Questionnaire 15 (PHQ-15)
Publikováno v:
American Journal of Health-System Pharmacy. 50:106-108
The stability of ondansetron hydrochloride in extemporaneously prepared oral solutions containing orange juice, cola, or cherry syrup was determined. Solutions were prepared by adding ondansetron hydrochloride to orange juice, cola, or cherry syrup t
Autor:
M, Camilleri, E A, Mayer, D A, Drossman, A, Heath, G E, Dukes, D, McSorley, S, Kong, A W, Mangel, A R, Northcutt
Publikováno v:
Alimentary pharmacologytherapeutics. 13(9)
No currently available treatment provides consistent relief of irritable bowel syndrome. Colonic sensory and motor function are modulated partly through 5HT3-receptors.To evaluate effects of the 5HT3-receptor antagonist, alosetron, in irritable bowel
Autor:
G E, Dukes
Publikováno v:
Pharmacotherapy. 17(5)
Autor:
K M, Jones, E, Liao, K, Hohneker, S, Turpin, M M, Henry, K, Selinger, P H, Hsyu, R C, Boucher, M R, Knowles, G E, Dukes
Publikováno v:
Pharmacotherapy. 17(2)
To compare the pharmacokinetics and systemic exposure of nebulized and oral amiloride in adolescents and adults with mild to moderate cystic fibrosis (CF).Open-label, randomized, two-way crossover, single-dose pharmacokinetic study.University hospita
Autor:
W D, Figg, G E, Dukes, H R, Lesesne, S W, Carson, S S, Songer, J F, Pritchard, D J, Hermann, J R, Powell, L J, Hak
Publikováno v:
Pharmacotherapy. 15(6)
To compare three quantitative metabolic markers used to assess hepatic function, indocyanine green (ICG), a high-extraction marker; antipyrine, a low-extraction marker; and dextromethorphan, a P-450IID6 marker, with the clinically used Pugh's classif
Autor:
P E, Warner, K L, Brouwer, E K, Hussey, G E, Dukes, W D, Heizer, K H, Donn, I M, Davis, J R, Powell
Publikováno v:
Pharmaceutical research. 12(1)
Sumatriptan exhibits low oral bioavailability partly due to presystemic metabolism, which may vary with regional differences in metabolic activity throughout the gastrointestinal tract. This study evaluated sumatriptan absorption in humans after admi
Publikováno v:
Southern medical journal. 86(5)
Ondansetron hydrochloride is a new serotonin receptor antagonist that is effective in preventing emesis associated with cancer chemotherapy. The antiemetic effect appears to be exerted through a peripheral vagal blocking within the gastrointestinal t
Autor:
B J, Zarowitz, P H, Vlasses, G E, Dukes, P, Gal, W A, Miller, W C, Porter, D R, Rush, P, Schneider, R L, Talbert
Publikováno v:
Pharmacotherapy. 13(3)
Certification of pharmacotherapy specialists is proceeding smoothly. Modifications to the examination process, which include reapportioning domains, offering the examination at several sites, and establishing the recertification process, have occurre