Zobrazeno 1 - 10
of 20
pro vyhledávání: '"G E, Billman"'
Autor:
Donal S. O'Leary, Robert D. Foreman, Harold D. Schultz, Jeffrey L. Ardell, G. E. Billman, Irving H. Zucker, John A. Armour, Peng Sheng Chen, Michael C. Andresen, Kenji Sunagawa, Hani N. Sabbah, Neil Herring
Publikováno v:
The Journal of Physiology. 594:3877-3909
Neuronal elements distributed throughout the cardiac nervous system, from the level of the insular cortex to the intrinsic cardiac nervous system, are in constant communication with one another to ensure that cardiac output matches the dynamic proces
Autor:
G E, Billman
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 2(12)
Kanebo is investigating KB-R7943, a Na+/Ca2+ ion exchange inhibitor, for the potential treatment of ischemia and reperfusion injury. It inhibited the outward Na+/Ca2+ exchange current (iNCX) more potently than the inward current under unidirectional
Autor:
G E, Billman, R A, Altschuld
Publikováno v:
Cardiologia (Rome, Italy). 43(8)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(3)
The activation of the ATP-sensitive potassium channel (KATP) during myocardial ischemia leads to potassium efflux, reductions in action potential duration and the formation of ventricular fibrillation (VF). Drugs that inactivate KATP should prevent t
Publikováno v:
Circulation. 96(6)
The ventricular myocardium contains functional beta2-adrenergic receptors that when activated increase intracellular Ca2+ transients. Because elevated Ca2+ has been implicated in the induction of ventricular fibrillation (VF), it is possible that the
Autor:
G E, Billman, R L, Hamlin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(3)
Calcium channel antagonists can reduce calcium overload induced by myocardial ischemia and thereby protect against malignant arrhythmias. However, these drugs may also adversely affect cardiac contractile function. Mibefradil is a new calcium antagon
Autor:
G E, Billman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(1)
Cocaine-induced increases in catecholamines and the resulting enhanced activation of myocardial adrenergic receptors could contribute significantly to the formation of ventricular fibrillation (VF). In order to test this hypothesis, a 2-min coronary
Publikováno v:
Biochemistry and molecular biology international. 30(5)
S-Nitrosoglutathione, a possible intermediate in the pharmacological mechanisms of many vasodilators, undergoes hemolysis at pH 7.4 and 37 degrees C to give oxidized glutathione and nitric oxide with a second-order rate constant of approximately 3 x
Autor:
G E, Billman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(1)
It is increasingly apparent that cocaine can provoke lethal cardiac events, including ventricular fibrillation (VF). Cocaine-induced accumulation of intracellular calcium could contribute significantly to the development of these lethal arrhythmias.
Autor:
G E, Billman
Publikováno v:
Journal of cardiovascular pharmacology. 18
Calcium-channel antagonists are widely used in the treatment of supraventricular tachyarrhythmias. The potential benefits of these agents in the management of ventricular arrhythmias, however, are not widely appreciated. Ventricular arrhythmias resul