Zobrazeno 1 - 10
of 13
pro vyhledávání: '"G E, Arteel"'
Autor:
J A Raleigh, Y. Iimuro, C Wall, K T Knecht, H D Connor, Y. Adachi, R P Mason, G E Arteel, Moritz V. Frankenberg, D. Forman, B. U. Bradford, Ronald G. Thurman
Publikováno v:
Frontiers in Bioscience. 4:e42-46
Alcohol treatment results in increases in the release of endotoxin from gut bacteria and membrane permeability of the gut to endotoxin, or both. Females are more sensitive to these changes. Elevated levels of endotoxin activate Kupffer cells to relea
Autor:
Min Lin, M. von Frankenberg, R. M. Gallucci, Z. Zhong, R P Mason, Hide Tsukamoto, H. Kono, B Stefanovic, B. U. Bradford, J A Raleigh, David A. Brenner, R. G. Thurman, Y. Iimuro, M. Luster, D. Forman, C. Wall, G E Arteel, N. Enomoto, J. J. Lemasters, K. Ikejima, M. Kadiiska, Y. Adachi
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:766-768
Autor:
G. E. Arteel, R. A. Rippe, B. Schnabl, Matthias Froh, Erwin Gäbele, Marcus Mühlbauer, C Hellerbrand, Reiner Wiest
Publikováno v:
Zeitschrift für Gastroenterologie. 43
Autor:
Z, Zhong, G E, Arteel, H D, Connor, P, Schemmer, S C, Chou, J A, Raleigh, R P, Mason, J J, Lemasters, R G, Thurman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
Disturbances in hepatic microcirculation increase graft injury and failure; therefore, this study evaluates the effects of ethanol on microcirculation after liver transplantation. Donor rats were given one dose of ethanol (5 g/kg) by gavage 20 h befo
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
Kupffer cell-dependent injury in livers gently manipulated during harvest develops upon transplantation; however, underlying mechanisms remain unknown. Thus, the purpose of this study was to identify factors involved in mechanisms of injury. Livers f
Publikováno v:
Radiation research. 151(5)
Pimonidazole binding was compared with oxygen electrode measurements and with measurements of the radiobiologically hypoxic fraction in C3H mammary tumors in which oxygenation was manipulated by means of subjecting tumor-bearing CDF1 mice to air brea
Publikováno v:
Molecular pharmacology. 55(4)
Ethanol increases free radical formation; however, it was recently demonstrated that it also causes extensive hypoxia in rat liver in vivo. To address this issue, it was hypothesized that peroxynitrite formed in normoxic periportal regions of the liv
Autor:
R G, Thurman, B U, Bradford, Y, Iimuro, K T, Knecht, G E, Arteel, M, Yin, H D, Connor, C, Wall, J A, Raleigh, M V, Frankenberg, Y, Adachi, D T, Forman, D, Brenner, M, Kadiiska, R P, Mason
Publikováno v:
Journal of gastroenterology and hepatology.
Previous research from this laboratory using a continuous enteral ethanol (EtOH) administration model demonstrated that Kupffer cells are pivotal in the development of EtOH-induced liver injury. When Kupffer cells were destroyed using gadolinium chlo
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(2)
Glycine prevents hepatic damage caused by hypoxia-reoxygenation, diminishes mortality due to endotoxin and minimizes alcoholic liver injury by decreasing blood ethanol. Our purpose was to investigate the effect of dietary glycine during recovery from
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(3)
Tacrine is an acetylcholinesterase inhibitor approved for the treatment of Alzheimer's disease. Unfortunately, reversible hepatotoxicity in about 30% of patients at therapeutic doses limits clinical use. The purpose of this study was to develop and c