Zobrazeno 1 - 10
of 44
pro vyhledávání: '"G Domuta"'
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics.
Objectives In this paper we investigated the effect of indomethacin, acetazolamide and their combination in vitro and in vivo on carbonic anhydrase (CA) isozymes. Method In vitro experiments followed the effect of the two substances at concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1ff71b7078f2b795d14edc800e6339
https://doi.org/10.5414/cpp39265
https://doi.org/10.5414/cpp39265
Publikováno v:
Physiological research. 50(4)
Previous data concerning the action of calcium (Ca) on gastric acid secretion (GAS) indicated that calcium ions increase GAS elicited by gastrin released through a vagal mechanism, and also by a direct effect on parietal cells. Our research showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a8a3b06a3acd72c5d0db6221673adbc
https://pubmed.ncbi.nlm.nih.gov/11551141
https://pubmed.ncbi.nlm.nih.gov/11551141
Publikováno v:
International journal of clinical pharmacology and therapeutics. 39(6)
In this paper we investigated the effect of indomethacin, acetazolamide and their combination in vitro and in vivo on carbonic anhydrase (CA) isozymes.In vitro experiments followed the effect of the two substances at concentrations between 10(-8)-10(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0f0fe9c8321ba1662cd339c8ea7c2e9
https://pubmed.ncbi.nlm.nih.gov/11430635
https://pubmed.ncbi.nlm.nih.gov/11430635
Publikováno v:
Drugs under experimental and clinical research. 27(2)
Carbonic anhydrase (CA) is a zinc enzyme that catalyses the reversible hydration reaction of CO2 and plays a major role in the acid-base balance. We have previously shown that certain vasoconstrictive therapeutic agents increase CA I activity whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf9a7c8960349aa2ead6ec1f730b6596
https://pubmed.ncbi.nlm.nih.gov/11392054
https://pubmed.ncbi.nlm.nih.gov/11392054
Publikováno v:
Cardiovascular drugs and therapy. 14(5)
Calcium channel blockers are a group of drugs used for the treatment of hypertension. Carbonic anhydrase (CA) I detected in vascular smooth muscle and in other cells in the organism has a major role in the acid-base balance and in vascular processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13d99988704085d4854310e5ff0fe134
https://pubmed.ncbi.nlm.nih.gov/11101200
https://pubmed.ncbi.nlm.nih.gov/11101200
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 52(5)
Cysteamine is known as the most efficient substance in producing experimental duodenal ulcers reaching 100% after a single dose administration in rats. It is also described the acid hypersecretion and the duodenal mucosa blood flow decrease after cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::621973ba87ddd8d1fcba00036793a775
https://pubmed.ncbi.nlm.nih.gov/11089894
https://pubmed.ncbi.nlm.nih.gov/11089894
Publikováno v:
Research communications in molecular pathology and pharmacology. 105(3)
A classification of diuretics mainly comprises mercurials; carbonic anhydrase inhibitors, thiazide diuretics, loop diuretics, inhibitors of renal epithelial Na+ channels and antagonists of mineralocorticoid receptors. We studied in this paper the rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b5423376fd8d20cbe0e4acc3636b6dc
https://pubmed.ncbi.nlm.nih.gov/10954127
https://pubmed.ncbi.nlm.nih.gov/10954127
Publikováno v:
Drugs under experimental and clinical research. 25(6)
Five years ago, our in vitro and in vivo studies demonstrated for the first time that diuretic agents such as furosemide, hydrochlorothiazide, amiloride, triamterene and spironolactone inhibit carbonic anhydrase (CA) I, II and renal CA IV by a direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a546ebaffd5494238657aa7bc97592d6
https://pubmed.ncbi.nlm.nih.gov/10713865
https://pubmed.ncbi.nlm.nih.gov/10713865
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
In this study our experiments followed in vitro and in vivo the effect of omeprazole on purified and erythrocyte carbonic anhydrase (CA) I and II isozymes, as well as on gastric mucosa CA IV in humans. Our in vitro results show that omeprazole-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6ee26914764fb8532a18036010b0831
https://pubmed.ncbi.nlm.nih.gov/10411559
https://pubmed.ncbi.nlm.nih.gov/10411559
Publikováno v:
International journal of clinical pharmacology and therapeutics. 37(6)
In this paper we investigated in humans and in animals the in vitro and in vivo effect of omeprazole upon purified and erythrocyte carbonic anhydrase (CA) I and II isozymes, as well as on gastric mucosa CA IV.In vitro, we observed the effect of omepr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59543074833b0c10a0474c1aef07d644
https://pubmed.ncbi.nlm.nih.gov/10395120
https://pubmed.ncbi.nlm.nih.gov/10395120