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Cortical and subcortical chemical pathology in Alzheimer's disease as assessed by multislice proton magnetic resonance spectroscopic imaging

Autor: J.H. Duyn, L. Verhagen Metman, Nicholas J. Patronas, Alessandro Bertolino, G. Di Chiro, T. N. Chase, Simona Bonavita, N. Lundbom, Gioacchino Tedeschi

Publikováno v: Neurology. 47:696-704

Background: Multislice proton magnetic resonance spectroscopic imaging (1H-MRSI) permits the simultaneous acquisition of N-acetylaspartate (NA), choline (Cho), creatine/phosphocreatine (Cre), and lactate (Lac) signal intensities from four 15-mm slice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dfe0d27f5bbec9f5bc1a4e7d77c14e
https://doi.org/10.1212/wnl.47.3.696

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Decreased cerebral glucose metabolism in patients with brain tumors: an effect of corticosteroids

Autor: Luigi Aloj, G. Di Chiro, Arturo Brunetti, Ramesh Raman, Michael J. Fulham, Andrew J. Dwyer

Publikováno v: Journal of Neurosurgery. 83:657-664

✓ The authors measured cerebral glucose metabolism (CMRglu) using [18F]fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) in patients with brain tumors to evaluate the effect of exogenous corticosteroids (in this instance, dexamethasone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b15d44e611399398739f15e271931e
https://doi.org/10.3171/jns.1995.83.4.0657

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Transsynaptic Reduction in N-Acetyl-Aspartate in Cerebellar Diaschisis

Autor: G. Di Chiro, Jeffrey R. Alger, J.H. Duyn, M. J. Dietz, H. H.-L. Shih, Michael J. Fulham

Publikováno v: Journal of Computer Assisted Tomography. 18:697-704

Objective To determine if the transneuronal cerebellar hemispheric metabolic asymmetry seen in crossed cerebellar diaschisis, and readily detected with positron emission tomography (PET), is associated with alterations in metabolite signal intensitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::439bf6694daa1c595867657a20eea227
https://doi.org/10.1097/00004728-199409000-00004

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MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys

Autor: Robert J. Plunkett, Krzysztof S. Bankiewicz, Robert S. Miletich, Joseph A. Frank, Mario Quarantelli, G. Di Chiro, Irwin J. Kopin

Publikováno v: Annals of Neurology. 35:689-697

Exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can cause an acute chemical toxicity resulting in a parkinsonian state in humans and nonhuman primates. We wished to assess whether the toxicity from MPTP is associated with changes on m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c1bcf1069218df9fd37c4c7eb814a0
https://doi.org/10.1002/ana.410350609

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Histopathologic correlates of abnormal water diffusion in cerebral ischemia: diffusion-weighted MR imaging and light and electron microscopic study

Autor: Carlo Pierpaoli, I. Linfante, A. Righini, G. Di Chiro, Jung Hwa Tao-Cheng, Jeffry R. Alger

Publikováno v: Radiology. 189:439-448

PURPOSE: To correlate the findings on diffusion-weighted magnetic resonance (MR) images with the cytologic and histologic findings in ischemic tissue. MATERIALS AND METHODS: A photochemical model of cerebral infarction in rats was studied with diffus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9689189f358f6e910298596aafea327b
https://doi.org/10.1148/radiology.189.2.8210373

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Neuroimaging of juvenile pilocytic astrocytomas: an enigma

Autor: J Nishimiya, J W Melisi, Andrew J. Dwyer, G. Di Chiro, Michael J. Fulham

Publikováno v: Radiology. 189:221-225

To present the imaging, metabolic, and clinical data obtained in five patients with juvenile pilocytic astrocytomas (JPAs) and discuss the paradoxical neuroimaging findings.Five patients with JPAs who had undergone structural imaging and fluorine-18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c6f0358eefa70a2ed2f9d44d92ccbe
https://doi.org/10.1148/radiology.189.1.8372197

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T1 and t2 of ferritin at different field strengths: effect on mri

Autor: Josef Vymazal, C McRill, Olga Zak, C Shen, G. Di Chiro, Rodney A. Brooks

Publikováno v: Magnetic Resonance in Medicine. 27:368-374

Nuclear magnetic relaxation times T1 and T2 were measured in ferritin solutions at field strengths from 0.04 to 1.5 T. T1 was relatively constant, but 1/T2 increased linearly with field strength, in agreement with earlier MRI observations in the monk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f9e5d2eb6d5ff8c2d28b6c343dde80
https://doi.org/10.1002/mrm.1910270218

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In vivo study of nmda-sensitive glutamate receptor by fluorothienylcycloexylpiperidine, a possible ligand for positron emission tomography

Autor: Erminio Costa, B. R. De Costa, Alessandro Guidotti, C. Ferrarese, G. Di Chiro, Michael J. Fulham, Robert S. Miletich, Kenner C. Rice

Publikováno v: Neuropharmacology. 30:899-905

As a preliminary to positron emission tomography (PET) studies of excitatory amino acid neurotransmission, N-methyl-d-aspartate (NMDA)-sensitive glutamate receptors of mice and rats were labelled in vivo with [3H]fluorothienylcycloexylpiperidine (FTC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::965097009e8ae7a4e4d5314cee8d7d56
https://doi.org/10.1016/0028-3908(91)90125-u

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