Zobrazeno 1 - 10
of 39
pro vyhledávání: '"G D Yancopoulos"'
Autor:
J. M. Orengo, A. R. Radin, V. Kamat, A. Badithe, L. H. Ben, B. L. Bennett, S. Zhong, D. Birchard, A. Limnander, A. Rafique, J. Bautista, A. Kostic, D. Newell, X. Duan, M. C. Franklin, W. Olson, T. Huang, N. A. Gandhi, L. Lipsich, N. Stahl, N. J. Papadopoulos, A. J. Murphy, G. D. Yancopoulos
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Allergen-specific immunotherapy is used to treat patients affected by acute immunoglobulin E (IgE) responses, but the function mechanism is unclear. Here the authors show that the administration of two cat allergen-specific IgGs reduces allergic resp
Externí odkaz:
https://doaj.org/article/4d30f5e885654cfb894aa83d96ba2276
Autor:
Elkan R. Gamzu, Shinji Hadano, Alan I. Faden, Kazunori Tanaka, Amanda M. VanDenburgh, Veronica L. Todaro, Bruce J. Kinon, Robin Elliott, Krishna Mettu, Pradeep Sahota, Arch G. Mainous, Bogdan A. Stoica, Barbara E. Herr, Ilya Lipkovich, Robert G. Robinson, Hitoshi Osuga, Susan Abu-Shakra, Mandeep Garewal, John P. Houston, Sergio E. Starkstein, Rachel L. Richesson, Daniel W. Smith, Herbert Marini, Manjamali Sivaraman, Mitchell F. Brin, Tatiana Galperin, Rebecca R. Seltzer, Selma C. Kunitz, S. J. Wiegand, Richard Torres, Toby Miller, Jordan J. Elm, Stanley T. Fricke, Robert C. Griggs, S. D. Croll, D. Badman, Scott P. Runyon, K. D. Anderson, Sara Kollack-Walker, Ricardo E. Jorge, Harumi Sakai, Joh-E Ikeda, Esteban Fridman, Virginia L. Stauffer, Ben-Zion Krimchansky, T. Jackson, Richard S.E. Keefe, John van Meter, Mendel Tuchman, Kimberly R. Byrnes, Yoshinori Okada, Michael A. Rogawski, Ayichew Hailu, J. Vercollone, Jonna Ahl, A. J. Murphy, Frederick Beddingfield, Mariana Bonetto, Asako Otomo, Barbara C. Tilley, Haya Ascher-Svanum, Rafal Kaminski, G. D. Yancopoulos, Mark Batshaw, Andrea L. Gropman
Publikováno v:
Neurotherapeutics
Publikováno v:
Journal of Neurochemistry. 65:10-22
We have isolated several new genes that are specifically expressed by oligodendrocytes in the CNS. This was achieved by differential screening of a rat spinal cord cDNA library with probes derived from normal and from oligodendrocyte-free spinal cord
Publikováno v:
Journal of Biological Chemistry. 269:30370-30377
Brain-derived neurotrophic factor (BDNF) interacts with the TrkB receptor tyrosine kinase, the tyrosine kinase domain of which has homology with the insulin receptor subfamily of protein kinases. This includes the conservation of three regulatory tyr
Autor:
F. Wong, Frederick W. Alt, Kenneth B. Kaplan, A. Rolink, F. Melchers, S. Gillis, G D Yancopoulos, Maureen A. Morrow, Gwo-Hwa Lee, E. M. Oltz
Publikováno v:
The EMBO Journal. 11:2759-2767
We describe a novel regulatory myosin light chain gene (termed precursor lymphocyte-specific regulatory light chain or PLRLC) that is expressed specifically in precursor B and T lymphocytes. PLRLC is the first example of a regulatory myosin light cha
Autor:
E. M. Oltz, Paul B. Rothman, Gary Rathbun, G D Yancopoulos, Maureen A. Morrow, Jeffrey E. Berman, Roger Smith, Gwo-Hwa Lee, Ami Okada, Rusty Lansford
Publikováno v:
Proceedings of the National Academy of Sciences. 87:5759-5763
We have utilized subtractive hybridization to isolate 16 distinct cDNA sequences representing genes expressed in pre-B-cell lines but not myeloma cell or fibroblast lines. These sequences represent RNA transcripts that vary in abundance in pre-B-cell
Autor:
Susan E. Prockop, Leonore A. Herzenberg, Garry P. Nolan, S C Li, Roberta R. Pollock, Frederick W. Alt, G D Yancopoulos
Publikováno v:
Molecular and Cellular Biology. 10:1697-1704
We describe two retroviral vector-based recombination substrate systems designed to assay for lymphoid VDJ recombinase activity in cultured cells. Both substrates incorporate a constitutive dominant marker gene (the simian virus promoter-driven neo g
Autor:
P C, Maisonpierre, L, Belluscio, S, Squinto, N Y, Ip, M E, Furth, R M, Lindsay, G D, Yancopoulos
Publikováno v:
Science. 247:1446-1451
The development and maintenance of the nervous system depends on proteins known as neurotrophic factors. Although the prototypical neurotrophic factor, nerve growth factor (NGF), has been intensively studied for decades, the discovery and characteriz
Publikováno v:
The Journal of Experimental Medicine
We have previously demonstrated a dramatic preference for utilization of the most JH-proximal VH gene segments in the newborn liver versus adult spleen. We now examine in detail the relative expression of different VH gene families throughout ontogen
Autor:
K D, Anderson, P D, Lambert, T L, Corcoran, J D, Murray, K E, Thabet, G D, Yancopoulos, S J, Wiegand
Publikováno v:
Journal of neuroendocrinology. 15(7)
Similar to leptin, ciliary neurotrophic factor (CNTF) suppresses appetite and selectively reduces body fat in leptin-deficient ob/ob mice. To assess the relative importance of specific regions of the hypothalamus in mediating these effects, we admini