Zobrazeno 1 - 10 of 19 pro vyhledávání: '"G D McIntyre"'
1
Rapid development of affinity matured monoclonal antibodies using RIMMS
Autor: G D McIntyre, Katherine E. Kilpatrick, Bruce Caterson, S A Wring, D H Walker, M D Macklin, Jui-Lan Su, B R Champion, J A Payne
Publikováno v: Hybridoma. 16(4)
Affinity matured murine monoclonal antibody producing cell lines can now be rapidly generated using a novel repetitive, multiple site immunization strategy designated RIMMS. RIMMS capitalizes on rapid hypermutation and affinity maturation events whic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e300750e713040e26ff8872f18ceedfe
https://pubmed.ncbi.nlm.nih.gov/9309429
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2
Activation of human cytolytic cells through CD2/T11. Comparison of the requirements for the induction and direction of lysis of tumor targets by T cells and NK cells
Autor: C F Scott, S Bolender, G D McIntyre, J Holldack, J M Lambert, Y P Venkatesh, C Morimoto, J Ritz, S F Schlossman
Publikováno v: The Journal of Immunology. 142:4105-4112
We studied the mechanisms whereby human T cells and NK cells are activated and directed to lyse tumor targets through the CD2 (T11/E-rosette) Ag. Using two cloned NK lines, we showed that these cells, as had previously been shown for T cells, could b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5df1eec61ee27f5f0665216573a9540f
https://doi.org/10.4049/jimmunol.142.11.4105
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3
Plasma atrial natriuretic peptide concentrations during exercise in sodium replete and deplete normal man
Autor: Brenda J. Leckie, John G.F. Cleland, S.G. Ball, J. I. S. Robertson, G. Tonolo, A. M. Richards, Henry J. Dargie, G. D. Mcintyre
Publikováno v: Clinical Science. 72:159-164
1. To explore the effects of exercise on plasma atrial natriuretic peptide (ANP) concentrations, eight normotensive volunteers performed maximal treadmill exercise in sodium replete and deplete states. 2. Baseline immunoreactive plasma ANP concentrat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991374f147ea117bbdc45928ada6f8b2
https://doi.org/10.1042/cs0720159
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5
Radio-lmmunoassay for Plasma Alpha Human Atrial Natriuretic Peptide: A Comparison of Direct and Pre-Extracted Methods
Autor: Brenda J. Leckie, Arthur Mark Richards, G. D. Mcintyre, J. I. A. Robertson, G. Tonolo
Publikováno v: Journal of Hypertension. 5:227-236
Plasma atrial natriuretic peptide (ANP) concentrations were measured by both direct radio-immunoassay and with pre-extraction of the peptide from plasma using C18 reverse phase columns. Peptide concentrations were measured in normal subjects (includi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa70d6df23fb005db52d8995914a2e8d
https://doi.org/10.1097/00004872-198704000-00015
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6
Renin and Inactive Renin (Prorenin) in the Plasma of Patients with Malignant Renal Tumours
Autor: R. Carachi, G. B. M. Lindop, W. D. Millan, G. D. McIntyre, Brenda J. Leckie
Publikováno v: Clinical and Experimental Hypertension. Part A: Theory and Practice. 9:1325-1332
Plasma active and inactive renin (prorenin) concentrations were measured in 26 adults with renal carcinoma and 8 children with nephroblastoma. In patients with carcinoma, plasma total renin concentration was slightly raised in 8 patients and markedly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220f3245c3d983f53ed9e3aaf67a2549
https://doi.org/10.3109/10641968709158986
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7
Evidence from peptide mapping for a human renin zymogen
Autor: G. D. McIntyre, Subhendu Chaudhuri, John R. Coggins
Publikováno v: FEBS Letters. (2):439-442
Data obtained from peptide mapping of the active and inactive forms of human renin show that there are extensive regions of common sequence in the two forms of the enzyme, and are consistent with the hypothesis that inactive renin is a renin zymogen.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4de8c3e71af9a66245006a82ccee9a
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8
Plasma atrial natriuretic peptide: responses to modest and severe sodium restriction
Autor: A M, Richards, G, Tonolo, J G, Cleland, B J, Leckie, G D, McIntyre, M, Ingram, H J, Dargie, S G, Ball, J I, Robertson
Publikováno v: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 4(6)
Plasma atrial natriuretic peptide (ANP), active renin and aldosterone concentrations were measured during modest and severe sodium restriction in 16 normal volunteers. Eight volunteers took, in two separate 4-day periods, diets containing 200 and 15
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1f2bca6dce950517d57c741718c45d2
https://pubmed.ncbi.nlm.nih.gov/2956392
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9
Immunocytochemistry of renin in renal tumours
Autor: D. Murray, G. D. McIntyre, D. W. M. Millan, A. A. M. Gibson, G. B. M. Lindop, Brenda J. Leckie
Publikováno v: Clinical and experimental hypertension. Part A, Theory and practice. 9(8-9)
We used a panel of two polyclonal antisera and two monoclonal antibodies to human renin to assess the tissue distribution of immunoreactive renin in a range of tumours and normal human tissues. The only tissue showing positive staining for renin was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462f8083ef5339237c860e5442aa1fb7
https://pubmed.ncbi.nlm.nih.gov/2820624
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