Zobrazeno 1 - 10
of 12
pro vyhledávání: '"G D, van Rossum"'
Publikováno v:
Journal of cellular biochemistry. 81(1)
Heterotrimeric G protein G12 stimulates diverse physiological responses including the activities of Na+/H+ exchangers and Jun kinases. We have observed that the expression of the constitutively activated, GTPase-deficient mutant of Galpha(12) (Galpha
Publikováno v:
European journal of cell biology. 64(2)
Rat hepatocytes in primary monolayer culture have been studied by a combination of physiological and morphological approaches under conditions affecting ion transport and cell volume. A concentration of ouabain completely inhibiting the coupled trans
Autor:
H I, Yeh, G D, van Rossum
Publikováno v:
Hepatology (Baltimore, Md.). 13(3)
We have studied the mechanism by which liver Golgi apparatus maintains the acidity of its contents, using a subcellular fraction from rat liver highly enriched in Golgi marker enzymes. Proton accumulation (measured by quenching of acridine-orange flu
Autor:
M A, Russo, G D, van Rossum
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 54(6)
The development of cellular damage in response to ethacrynic acid and to amytal has been studied in slices of rat liver. After a preincubation at 1 degree C, the slices were incubated with or without the agents at 38 degrees C. Control slices showed
Inhibition of sodium-potassium-activated adenosine 5'-triphosphatase and ion transport by adriamycin
Publikováno v:
Cancer research. 39(1)
The antitumor antibiotic Adriamycin is a potent inhibitor of the sodium-potassium-activated adenosine triphosphatase of native heart microsomes. Adriamycin also inhibits potassium transport (although not sodium transport) in slices of kidney cortex.
Publikováno v:
Cancer research. 36(11 Pt 1)
The changes in water and electrolyte content of slices of Morris hepatoma 3924A induced by various conditions of incubation have been compared with the ultrastructural appearance of the tissue. Incubation at 1 degrees led to an increase of water, Na+
Publikováno v:
British journal of experimental pathology. 69(2)
The subcellular distribution and ultrastructural effects of lead have been studied in the kidneys and liver of rats given lead acetate (600 ppm Pb2+) in their drinking water for 6 months. Control rats were given sodium acetate. Tissue samples were fi
Publikováno v:
Cancer research. 36(11 Pt 1)
Addition of increasing concentrations of glucose to slices of Morris hepatoma 3924A greatly stimulated aerobic lactate production and reduced respiration by 20%. Neither the adenine nucleotide content of the slices nor the calculated rate of adenosin
Autor:
G D, Van Rossum
Publikováno v:
Biochimica et biophysica acta. 110(2)
Publikováno v:
Cancer research. 33(5)