Zobrazeno 1 - 10
of 21
pro vyhledávání: '"G D, Talley"'
Autor:
M E Brousseau, S Santamarina-Fojo, B L Vaisman, D Applebaum-Bowden, A M Bérard, G D Talley, H B Brewer, Jr, J M Hoeg
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2537-2547 (1997)
Lecithin:cholesterol acyltransferase (LCAT) is an enzyme well known for its involvement in the intravascular metabolism of high density lipoproteins; however, its role in the regulation of apolipoprotein (apo) B-containing lipoproteins remains elusiv
Externí odkaz:
https://doaj.org/article/b352b7ce0aec4d8b8c8838cdea68e5bb
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 651-661 (1996)
Familial lipoprotein lipase (LPL) deficiency is an inherited disorder of lipoprotein metabolism characterized by hypertriglyceridemia and recurrent episodes of abdominal pain and pancreatitis. We have studied the genetic basis of LPL deficiency in a
Externí odkaz:
https://doaj.org/article/f3b3c559415b4b72ad34c68b0b2b62d5
Autor:
Stephen J. Demosky, G D Talley, Jeffrey M. Hoeg, Silvia Santamarina-Fojo, Boris L. Vaisman, Jian Wang, H. Bryan Brewer, Margaret E. Brousseau
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 8, Pp 1558-1567 (1998)
Familial hypercholesterolemia (FH), a disease caused by a variety of mutations in the low density lipopro- tein receptor (LDLr) gene, leads not only to elevated LDL- cholesterol (C) concentrations but to reduced high density lipoprotein (HDL)-C and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7f7c03692fba4225c1726590cf0395
https://doi.org/10.1016/s0022-2275(20)32184-2
https://doi.org/10.1016/s0022-2275(20)32184-2
Autor:
Deborah Applebaum-Bowden, Jeffrey M. Hoeg, Boris L. Vaisman, G D Talley, Margaret E. Brousseau, H B Brewer, Silvia Santamarina-Fojo, A M Bérard
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 12, Pp 2537-2547 (1997)
Lecithin:cholesterol acyltransferase (LCAT) is an enzyme well known for its involvement in the intravascular metabolism of high density lipoproteins; however, its role in the regulation of apolipoprotein (apo) B-containing lipoproteins remains elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7f157e1824ff8f9e1cb6352e96ef6d
http://www.sciencedirect.com/science/article/pii/S0022227520300389
http://www.sciencedirect.com/science/article/pii/S0022227520300389
Autor:
Bernhard Föger, H. Bryan Brewer, G D Talley, Catherine L. Parrot, Robert D. Shamburek, Silvia Santamarina-Fojo
Publikováno v:
Journal of Biological Chemistry. 272:27393-27400
In vitro studies have shown that plasma phospholipid transfer protein (PLTP) converts isolated human high density lipoprotein-3 (HDL3) into larger HDL particles and generates lipid-poor apoA-I containing nascent HDL. To evaluate the role of PLTP in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069de560f7e3422b16a0ad0364718d8c
https://doi.org/10.1074/jbc.272.43.27393
https://doi.org/10.1074/jbc.272.43.27393
Autor:
Silvia Santamarina-Fojo, A M Bérard, Robert D. Shamburek, Boris L. Vaisman, Beverly Paigen, Robert F. Hoyt, Alan T. Remaley, G D Talley, H. Bryan Brewer, Santica M. Marcovina, Bernhard Föger
Publikováno v:
Nature Medicine. 3:744-749
A subset of patients with high plasma HDL concentrations have enhanced rather than reduced atherosclerosis. We have developed a new transgenic mouse model overexpressing human lecithin-cholesteryl acyltransferase (LCAT) that has elevated HDL and incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c623972b8ce0c5565300091c02a510
https://doi.org/10.1038/nm0797-744
https://doi.org/10.1038/nm0797-744
Autor:
S.M. Meyn, Jorge Paiz, H B Brewer, Robert F. Hoyt, Naohiko Sakai, Silvia Santamarina-Fojo, Boris L. Vaisman, Christine A. Koch, G D Talley
Publikováno v:
Journal of Biological Chemistry. 272:7506-7510
We have established a mouse model for human LCAT deficiency by performing targeted disruption of the LCAT gene in mouse embryonic stem cells. Homozygous LCAT-deficient mice were healthy at birth and fertile. Compared with age-matched wild-type litter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ad8ff36c1b76b2f6a4cebd445add3c6
https://doi.org/10.1074/jbc.272.11.7506
https://doi.org/10.1074/jbc.272.11.7506
Autor:
L Previato, Klaus A. Dugi, R Ronan, O Guardamagna, Silvia Santamarina-Fojo, G D Talley, H B Brewer
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 9, Pp 1552-1560 (1994)
Lipoprotein lipase (LPL) is a complex enzyme consisting of multiple functional domains essential for the initial hydrolysis of triglycerides present in plasma lipoproteins. Previous studies have localized the catalytic domain of LPL, responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60040fb6abd5fe672325578cf25506c
https://doi.org/10.1016/s0022-2275(20)41153-8
https://doi.org/10.1016/s0022-2275(20)41153-8
Publikováno v:
Journal of Biological Chemistry. 267:25086-25091
Lipoprotein lipase (LPL), a key enzyme which initiates the hydrolysis of triglycerides present in chylomicrons and very low density lipoproteins, consists of multiple functional domains which are necessary for normal activity. The catalytic domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e813d7592b3d179d6279aceb2c354b25
https://doi.org/10.1016/s0021-9258(19)74009-5
https://doi.org/10.1016/s0021-9258(19)74009-5
Autor:
M E, Brousseau, J, Wang, S J, Demosky, B L, Vaisman, G D, Talley, S, Santamarina-Fojo, H B, Brewer, J M, Hoeg
Publikováno v:
Journal of lipid research. 39(8)
Familial hypercholesterolemia (FH), a disease caused by a variety of mutations in the low density lipoprotein receptor (LDLr) gene, leads not only to elevated LDL-cholesterol (C) concentrations but to reduced high density lipoprotein (HDL)-C and apol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44c72a63a873a358d9e9a6b34e59a24c
https://pubmed.ncbi.nlm.nih.gov/9717715
https://pubmed.ncbi.nlm.nih.gov/9717715