Zobrazeno 1 - 10
of 11
pro vyhledávání: '"G D, Rifkin"'
Autor:
Rodney Lusk, G. D. Rifkin, Robert Fekety, John Armstrong, Renu Toshniwal, John R. Ebright, Joseph Silva, Robert Browne, Maria Allo
Publikováno v:
Clinical Infectious Diseases. 3:S273-S281
Studies in humans and hamsters have shown that Clostridium difficile is the most important cause of antibiotic-associated colitis. A toxin produced by the organism is responsible for the disease and can be detected in the stools of patients. Proctosi
Publikováno v:
Gastroenterology. 75:422-424
A fecal toxin has previously been identified and implicated in the pathogenesis of clindamycin-induced cecitis in humans and hamsters. This report documents neutralization of the hamster toxin by Clostridium sordellii antitoxin and suggests its simil
Antibiotic-associated pseudomembranous colitis: an epidemiologic investigation of a cluster of cases
Autor:
P. F. Pierce, James M. Hughes, V. R. Dowell, Robert Fekety, R. Wilson, O. Nunez-Montiel, Joseph Silva, V. F. Garagusi, G. D. Rifkin
Publikováno v:
The Journal of infectious diseases. 145(2)
Ten cases of antibiotic-associated colitis (AAC) were identified at a hospital in Washington, D.C., from March 17 to May 9, 1979. No geographic clustering of cases was found, nor was an association with increased use of antibiotics demonstrated. Expo
Publikováno v:
The American journal of the medical sciences. 276(1)
Naturally acquired Brucella canis infection is believed to be uncommon, but is not readily diagnosed. A 55-year-old woman developed fever, abdominal pain, malaise, weakness, and anorexia eight weeks after her dog delivered stillborn pups. Blood cultu
Publikováno v:
Gut. 21(6)
A toxin produced by Clostridium difficile has been implicated in the pathogenesis of antibiotic-associated colitis in humans and experimental animals. This study was undertaken in order to define the sequential evolution of caecal mucosal lesions in
Publikováno v:
Gastroenterology. 76(2)
Toxins produced by Clostridium difficile have been implicated in the etiology of antibiotic-induced colitis. Clostridium difficile antitoxin is not available, but recent studies have shown that toxins present in the feces of patients with this diseas
Publikováno v:
The American journal of clinical nutrition. 32(1)
The hamster model of enterocolitis after the administration of clindamycin was used to study various drugs used in treatment of the disease in humans. Current evidence strongly suggests toxigenic, clindamycin-resistant Clostridium difficile is a caus
Autor:
G D, Rifkin
Publikováno v:
Archives of internal medicine. 140(6)
Two patients with previously undiagnosed agranulocytosis had rapidly fatal Clostridium septicum sepsis and neutropenic enterocolitis. This toxigenic organism has a known predilection for cecal lesions. The association reported herein suggests that C
Publikováno v:
Gastroenterology. 74(1)
The production of toxic substances by intestinal bacteria is one pathogenic mechanism proposed for antibiotic-associated colitis. We demonstrated the presence of a toxic substance(s) in the feces of hamsters developing clindamycin-induced enterocolit
Autor:
Robert Fekety, G. D. Rifkin, Maria Allo, Robert Browne, Joseph Silva, Renu Toshniwal, John Armstrong, John R. Ebright
Publikováno v:
Reviews of infectious diseases. 1(2)
Fifteen isolates of Clostridium difficile from hamsters and human patients were inhibited or killed by low concentrations of metronidazole, vancomycin, penicillin, and ampicillin; the isolates were often reesistant to tetracycline, cephalosporins, tr