Zobrazeno 1 - 3
of 3
pro vyhledávání: '"G D, Martyn"'
Autor:
G. Veggiani, R. Villaseñor, G. D. Martyn, J. Q. Tang, W. M. Krone, J. Gu, C. Chen, M. L. Waters, K. H. Pearce, T. Baubec, S. S. Sidhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Engineered chromodomains are promising probes to analyze histone methylation. Here the authors designed high-affinity chromodomains for enhanced genome-wide binding analysis, live-cell imaging and ultra-potent CRISPR-based gene repression.
Externí odkaz:
https://doaj.org/article/c874d75ba0bf4500b8d0f94e68765f16
Autor:
G. Veggiani, R. Villaseñor, G. D. Martyn, J. Q. Tang, M. W. Krone, J. Gu, C. Chen, M. L. Waters, K. H. Pearce, T. Baubec, S. S. Sidhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/16dbff1044e14403a67465eb69dd73f3
Autor:
G, Veggiani, R, Villaseñor, G D, Martyn, J Q, Tang, M W, Krone, J, Gu, C, Chen, M L, Waters, K H, Pearce, T, Baubec, S S, Sidhu
Publikováno v:
Nature communications. 13(1)
Histone methylation is an important post-translational modification that plays a crucial role in regulating cellular functions, and its dysregulation is implicated in cancer and developmental defects. Therefore, systematic characterization of histone