Zobrazeno 1 - 10
of 158
pro vyhledávání: '"G Campbell, Teskey"'
Autor:
Renaud C. Gom, Antis G. George, Sydney A. Harris, Pasindu Wickramarachchi, Dhyey Bhatt, Shaona Acharjee, Quentin J. Pittman, Matthew N. Hill, Roberto Colangeli, G. Campbell Teskey
Publikováno v:
Neurobiology of Stress, Vol 33, Iss , Pp 100678- (2024)
People with epilepsy often have psychiatric comorbidities that can significantly impair their quality of life. We previously reported that repeated seizure activity persistently alters endocannabinoid (eCB) signaling in the amygdala which accounts fo
Externí odkaz:
https://doaj.org/article/ae117a00074c4221a0c8f41e455c6adf
Autor:
Bianca R. Villa, Dhyey Bhatt, Marshal D. Wolff, Kwaku Addo-Osafo, Jonathan R. Epp, G. Campbell Teskey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Comorbidities during the period between seizures present a significant challenge for individuals with epilepsy. Despite their clinical relevance, the pathophysiology of the interictal symptomatology is largely unknown. Postictal severe hypox
Externí odkaz:
https://doaj.org/article/c1c8361e8030463093a76d1490ae5292
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Sudden unexpected death in epilepsy (SUDEP) is the leading epilepsy-related cause of premature mortality in people with intractable epilepsy, who are 27 times more likely to die than the general population. Impairment of the central control
Externí odkaz:
https://doaj.org/article/83a6b645b38c407fa366f4a129208f31
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Adult neurogenesis, the proliferation and integration of newly generated neurons, has been observed in the adult mammalian hippocampus of many species. Numerous studies have also found adult neurogenesis in the human hippocampus, but several
Externí odkaz:
https://doaj.org/article/eb7d181611ad42fcbbc4cd92bacd8562
Autor:
Renaud C. Gom, Dhyey Bhatt, Bianca R. Villa, Antis G. George, Alexander W. Lohman, Richelle Mychasiuk, Jong M. Rho, G. Campbell Teskey
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105335- (2021)
Objectives: A prolonged vasoconstriction/hypoperfusion/hypoxic event follows self-terminating focal seizures. The ketogenic diet (KD) has demonstrated efficacy as a metabolic treatment for intractable epilepsy and other disorders but its effect on lo
Externí odkaz:
https://doaj.org/article/160750426e64448285582cddf18a1ed6
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Seizures can result in a severe hypoperfusion/hypoxic attack that causes postictal memory and behavioral impairments. However, neither postictal changes to microvasculature nor Ca2+ changes in key cell types controlling blood perfusion have been visu
Externí odkaz:
https://doaj.org/article/1887ad402b024477bcbfdef289570e19
Publikováno v:
Journal of Neurophysiology. 128:727-737
Repetitive mild traumatic brain injuries (RmTBIs) are increasingly recognized to have long-term neurological sequelae in a significant proportion of patients. Individuals that have had RmTBIs exhibit a variety of sensory, cognitive, or behavioral con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7344b07e0740f5c4a9ee9c837bc898f9
https://doi.org/10.1152/jn.00533.2021
https://doi.org/10.1152/jn.00533.2021
Autor:
Cam Ha T. Tran, G. Campbell Teskey
Publikováno v:
Neuroglia. 2:36-47
Neurovascular coupling is a key control mechanism in cerebral blood flow (CBF) regulation. Importantly, this process was demonstrated to be affected in several neurological disorders, including epilepsy. Neurovascular coupling (NVC) is the basis for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15eafe934cd043c9a6c3ebf2908a5a3e
https://doi.org/10.3390/neuroglia2010005
https://doi.org/10.3390/neuroglia2010005
Autor:
Antis G. George, Jordan S. Farrell, Roberto Colangeli, Alexandra K. Wall, Renaud C. Gom, Mitchell T. Kesler, Cristiane Rodriguez de la Hoz, Bianca R. Villa, Tefani Perera, Jong M. Rho, Deborah Kurrasch, G. Campbell Teskey
Publikováno v:
Neuropharmacology. 231:109513
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a679b5eb60a90ed7e5bc038f75b3d3
https://doi.org/10.1016/j.neuropharm.2023.109513
https://doi.org/10.1016/j.neuropharm.2023.109513
Autor:
Sydney A. Harris, Antis G. George, Karlene T. Barrett, Morris H. Scantlebury, G. Campbell Teskey
Publikováno v:
EpilepsiaREFERENCES. 63(10)
In adult brain tissue, oxygen levels typically remain in the normoxic zone, but status epilepticus results in hyperoxia, whereas brief self-terminating seizures lead to postictal hypoxia. The dynamic changes in oxygen levels and the underlying mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062b14277cd2a95333ad4313629b92a1
https://pubmed.ncbi.nlm.nih.gov/35852401
https://pubmed.ncbi.nlm.nih.gov/35852401