Zobrazeno 1 - 10
of 34
pro vyhledávání: '"G C Palmer"'
Autor:
C. G. C. Palmer, S. Jagannathan
Publikováno v:
Anaesthesia. 71(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d83aad80551cc2661c437888b4345eb
https://pubmed.ncbi.nlm.nih.gov/27870178
https://pubmed.ncbi.nlm.nih.gov/27870178
Autor:
S. Jagannathan, C. G. C. Palmer
Publikováno v:
Anaesthesia. 72:413-414
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d373b49ba93c7411c8e8f2d4abc19fb9
https://doi.org/10.1111/anae.13820
https://doi.org/10.1111/anae.13820
Autor:
G. C. Palmer, Dan Widzowski
Publikováno v:
Amino acids. 19(1)
The success of the low affinity use-dependent NMDA receptor antagonists to reach clinical trials can be readily attributed to their wider margins of safety and lack of neurotoxicity at higher doses. Several mechanistic differences distinguish the low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5f035246b1657d8f68e52497f4032c
https://pubmed.ncbi.nlm.nih.gov/11026483
https://pubmed.ncbi.nlm.nih.gov/11026483
Autor:
G C, Palmer, R J, Murray, C L, Cramer, M L, Stagnitto, M K, Knowles, L R, Freedman, M S, Eismann, N, Mahmood, M, Balestra, A R, Borrelli, T J, Hudzik, D J, McCarthy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
A rational, chemical, synthetic effort to identify promising low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists for use as antiepileptic drugs led to the discovery of AR-R 15035AR, or [RS]-alpha-phenyl-2-pyridine-ethanamine.2HCl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7640a98edc976a3fa7c4cf18b0f614ee
https://pubmed.ncbi.nlm.nih.gov/9862762
https://pubmed.ncbi.nlm.nih.gov/9862762
Publikováno v:
Epilepsia. 37(6)
This study was designed to determine the possible abuse liability and phencyclidine-like effects of the low-affinity uncompetitive N-methyl-D-aspartate (NMDA) antagonists remacemide hydrochloride [(+/-)-2-amino-N-(1-methyl-1,2-diphenylethyl)-acetamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faf1c6f18e60a8852f47ce4c2a0232e8
https://pubmed.ncbi.nlm.nih.gov/8641231
https://pubmed.ncbi.nlm.nih.gov/8641231
Autor:
G C, Palmer, E C, Cregan, A R, Borrelli, E W, Harris, M L, Stagnitto, P, Colombo, F C, Kaiser, R J, Murray, R C, Griffith, J C, Strand
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(2)
2-Amino-N-(1,2-diphenylethyl)-acetamide hydrochloride (FPL 13950) has been demonstrated to have good anticonvulsant efficacy and a relative lack of acute side effects in rodents. Similar in structure to remacemide hydrochloride, it was also shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34d525f59dfead5ca586f236f8fcbd65
https://pubmed.ncbi.nlm.nih.gov/7636764
https://pubmed.ncbi.nlm.nih.gov/7636764
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 317
Intravenous injection of N-methyl-D,L-aspartic acid (NMDLA) into mice produces characteristic convulsions followed by death. The present study was designed to determine the degree of blockade of these seizures/mortality by compounds acting at various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5c3be7b8e5f4583e92b3bce197aa178
https://pubmed.ncbi.nlm.nih.gov/1456842
https://pubmed.ncbi.nlm.nih.gov/1456842
Autor:
K T, Muir, G C, Palmer
Publikováno v:
Epilepsy research. Supplement. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c478ee22fbec514ff3af7b5bfcc407dc
https://pubmed.ncbi.nlm.nih.gov/1777071
https://pubmed.ncbi.nlm.nih.gov/1777071
Autor:
G C, Palmer, E W, Harris, J J, Napier, M L, Stagnitto, G E, Garske, R C, Griffith, E A, Swinyard
Publikováno v:
Progress in clinical and biological research. 361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::895acd69bb5285d8764ac65978448d14
https://pubmed.ncbi.nlm.nih.gov/2290849
https://pubmed.ncbi.nlm.nih.gov/2290849
Publikováno v:
Journal of Neuroscience Research. 19:252-257
The present study was initiated to determine whether pretreatment of gerbils with calcium channel blockers, flunarizine and verapamil would prevent injury to cerebral ATPases following secondary ischemia consisting of 60-min bilateral clamping of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e95f5293f86519a5f05898231cd3ee
https://doi.org/10.1002/jnr.490190211
https://doi.org/10.1002/jnr.490190211