Zobrazeno 1 - 10
of 60
pro vyhledávání: '"G C Ford"'
Publikováno v:
Diabetologia. 49:543-551
In non-diabetic people, insulin levels in the liver are two-fold higher than those in the systemic circulation. In contrast, patients with type 1 diabetes have similar hepatic and systemic insulin levels because insulin is administered peripherally.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770672067f03606f9884295959f6356
https://doi.org/10.1007/s00125-005-0062-x
https://doi.org/10.1007/s00125-005-0062-x
Autor:
M. J. ADAMS, G. C. FORD, R. KOEKOEK, P. J. LENTZ, A. McPHERSON, M. G. ROSSMANN, I. E. SMILEY, R. W. SCHEVITZ, A. J. WONACOTI
Publikováno v:
Selected Papers of Michael G Rossmann with Commentaries ISBN: 9789814513340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe05fea54804e4e78b3fb986f00e3c30
https://doi.org/10.1142/9789814513357_0010
https://doi.org/10.1142/9789814513357_0010
Autor:
David P. Hornby, G. C. Ford
Publikováno v:
Current Opinion in Biotechnology. 9:354-358
Since the discovery that the DNA methyltransferase M. Hha I utilises a base flipping mechanism to expose its target cytosine during catalysis, this phenomenon has been observed in other nucleic acid modifying enzymes. The crystallographic analyses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf77d8feb03548b48a2de6cf69a00b2c
https://doi.org/10.1016/s0958-1669(98)80007-4
https://doi.org/10.1016/s0958-1669(98)80007-4
Autor:
G. C. Ford, Alisdair R Fernie, D. M. Lawson, Paul D. Hempstead, Pauline M. Harrison, S J Yewdall, Peter J. Artymiuk, David W. Rice
Publikováno v:
Journal of Molecular Biology. 268:424-448
Mammalian ferritins are 24-mers assembled from two types of polypeptide chain which provide the molecule with different functions. H(eavy) chains catalyse the first step in iron storage, the oxidation of iron(II). L(ight) chains promote the nucleatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85a8adeeb837deb61060842d2383dd78
https://doi.org/10.1006/jmbi.1997.0970
https://doi.org/10.1006/jmbi.1997.0970
Publikováno v:
Analytical Biochemistry. 247:228-236
A determinant of the accuracy of protein synthesis measurement using stable isotope is the purity of the protein under study. An Immunoaffinity chromatographic technique to sequentially purify human plasma albumin, fibrinogen, and apolipoprotein B-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2851174f9e260c4b7b2a304888f935
https://doi.org/10.1006/abio.1997.2086
https://doi.org/10.1006/abio.1997.2086
Publikováno v:
Journal of Clinical Investigation. 95:2926-2937
To elucidate the mechanism of insulin's anticatabolic effect in humans, protein dynamics were evaluated in the whole-body, splanchnic, and leg tissues in six C-peptide-negative type I diabetic male patients in the insulin-deprived and insulin-treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bffb883566e126ea65e72285c90e62c
https://doi.org/10.1172/jci118000
https://doi.org/10.1172/jci118000
Autor:
Venkatachalem Sathish, A. Barnes, Michael A. Thompson, G. C. Ford, Christina M. Pabelick, Dan F. Smelter, Y. S. Prakash, Amard J. Abcejo, K. J. Grim
Publikováno v:
British journal of anaesthesia. 109(3)
Background The i.v. anaesthetic propofol produces bronchodilatation. Airway relaxation involves reduced intracellular Ca2+ ([Ca2+]i) in airway smooth muscle (ASM) and lipid rafts (caveolae), and constitutional caveolin proteins regulate [Ca2+]i. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002fa5912c898c73433f30dbbbe3f46d
https://pubmed.ncbi.nlm.nih.gov/22542538
https://pubmed.ncbi.nlm.nih.gov/22542538
Autor:
Amyra Treffry, J. C. Livingstone, John R. Guest, Peter J. Artymiuk, J. M. A. Smith, Pauline M. Harrison, D. M. Lawson, S J Yewdall, Simon C. Andrews, J. Hirzmann, G. C. Ford
Publikováno v:
ChemInform. 22
Publisher Summary This chapter compares the structures of the iron cores and protein coats of ferritins and the hemoferritins of bacteria, and the current state of knowledge concerning mineralization processes in these molecules is discussed in relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca6388cecc95ad929e7c3e8caf8bd875
https://doi.org/10.1002/chin.199150348
https://doi.org/10.1002/chin.199150348
Publikováno v:
Biology of Metals. 4:95-99
The nature of the amino acids whose codons border introns in ferritin genes is novel; the disposition of these intron boundaries within the three-dimensional structure of the 24-subunit molecule differs significantly from that of other proteins. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c1d05cc67f12a7c264485838fa905f
https://doi.org/10.1007/bf01135385
https://doi.org/10.1007/bf01135385
Publikováno v:
British Journal of Surgery. 77:791-794
The counter-regulatory hormones, including glucagon, may be involved in the generation of postoperative negative nitrogen balance. We examined the influence of glucagon on whole body and forearm muscle protein kinetics, determined by L-[1–13C,15N]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f47adfd6c296ab7db21249135c0077
https://doi.org/10.1002/bjs.1800770723
https://doi.org/10.1002/bjs.1800770723