Zobrazeno 1 - 10
of 13
pro vyhledávání: '"G C, Visor"'
Publikováno v:
Pharmaceutical research. 2(2)
Electrochemical and spectrophotometric detectors for the reversed phase HPLC analysis of thimerosal in an ophthalmic formulation were evaluated with respect to response linearity, recovery, and lower limit of detection. The electrochemical oxidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::126aa5465829e75e3e8d2665f21a33dc
https://pubmed.ncbi.nlm.nih.gov/24272612
https://pubmed.ncbi.nlm.nih.gov/24272612
Autor:
L C, Yuan, G C, Visor
Publikováno v:
PDA journal of pharmaceutical science and technology. 51(1)
The antiviral drug 9-[2-(phosphonomethoxy)ethyl]adenine, PMEA, was developed as an intravenous product for the treatment of human immunodeficiency virus infection. During the course of stability monitoring, PMEA i.v. injection was found to undergo pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e226e8ba2b2775d03a7fb09e588f7b7
https://pubmed.ncbi.nlm.nih.gov/9099062
https://pubmed.ncbi.nlm.nih.gov/9099062
Publikováno v:
Pharmaceutical research. 11(6)
The bioavailability of PMEA from three oral formulations of the prodrug bis(POM)-PMEA has been evaluated in fasted male cynomolgus monkeys. The formulations examined included a hydroxypropyl-beta-cyclodextrin (HPBCD) complex, a PEG based cosolvent so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b36d905ea3c9047ab7caeaa423ab8198
https://pubmed.ncbi.nlm.nih.gov/7937523
https://pubmed.ncbi.nlm.nih.gov/7937523
Autor:
L C, Gu, E A, Erdös, H S, Chiang, T, Calderwood, K, Tsai, G C, Visor, J, Duffy, W C, Hsu, L C, Foster
Publikováno v:
Pharmaceutical research. 8(4)
The thermal stability of IL-1 beta in aqueous solution as a function of temperature (5-60 degrees C), pH (2-9), buffer (acetate, citrate, tris, and phosphate), and cyroprotectants (sugars, HSA) was investigated in this study. The analytical methodolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d21d825e4408ff53525b9622b2fa1a4
https://pubmed.ncbi.nlm.nih.gov/1871044
https://pubmed.ncbi.nlm.nih.gov/1871044
Publikováno v:
Journal of parenteral science and technology : a publication of the Parenteral Drug Association. 44(3)
The stability and delivery of IL-1 beta has been characterized in a polypropylene based syringe pump infusion system and in polyvinyl chloride based infusion bags, at concentrations ranging from 100 ng/mL to 1 microgram/mL. At higher concentrations (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0338453236037ca6b6106c7a9ae405a
https://pubmed.ncbi.nlm.nih.gov/2370622
https://pubmed.ncbi.nlm.nih.gov/2370622
Autor:
G C, Visor, K P, Tsai, M D, Miller, J, Duffy, T, Calderwood, D, Lokensgard, J, Killian, T, Malefyt, L, Gu, I, Massey
Publikováno v:
Lymphokine research. 9(3)
The development and characterization of a lyophilized dosage form for recombinant Interleukin-1 beta is described. Included in the evaluation of the drug product are accelerated and long-term stability studies utilizing a number of biophysical techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01255d4a71a123fcfd183f521c40d024
https://pubmed.ncbi.nlm.nih.gov/2398744
https://pubmed.ncbi.nlm.nih.gov/2398744
Publikováno v:
Drug Development and Industrial Pharmacy. 13:1329-1343
Nicardipine hydrochloride, a highly potent calcium entry channel blocker was administered intranasally to rats and rhesus monkeys. The Intranasal absorption of nicardipine in rats was studied with aqueous vehicles containing 0.1 M citrate buffer pH 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2cafab7840bce5a2b4c1f4c260eda41
https://doi.org/10.3109/03639048709068379
https://doi.org/10.3109/03639048709068379
Publikováno v:
Pharmaceutical research. 6(11)
Because of the limited stability of moexipril (RS-10085; 1) in aqueous solution, lyophilized parenteral formulations were evaluated as a function of pH in this study. In general, the lyophilized powder of 1 showed about two orders of magnitude less r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e93dd190651e495c2d6b30b70a76829
https://pubmed.ncbi.nlm.nih.gov/2594691
https://pubmed.ncbi.nlm.nih.gov/2594691
Publikováno v:
American journal of hospital pharmacy. 43(11)
The stability of 9-[(1,3-dihydroxy-2-propoxymethyl]) guanine sodium (ganciclovir sodium, also known as DHPG sodium) in two infusion solutions was studied. Lyophilized ganciclovir sodium 500 mg was reconstituted with sterile water 10 mL to give a theo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d564e83529c0df68933b3a749ba2b63a
https://pubmed.ncbi.nlm.nih.gov/3492139
https://pubmed.ncbi.nlm.nih.gov/3492139
Publikováno v:
Drug design and delivery. 2(2)
The solution phase interaction between ascorbic acid and the cardiotonic drug N-cyclohexyl-N-methyl-4(7-oxy 1,2,3,5-tetrahydroimidazol[2,1-b] quinazolin-2-one butyramide (RS-82856) was evaluated using a differential pulse voltammetric technique. Shif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54e70ff6e4d38a1c6c4694e3c7bc3675
https://pubmed.ncbi.nlm.nih.gov/2855568
https://pubmed.ncbi.nlm.nih.gov/2855568