Zobrazeno 1 - 10
of 255
pro vyhledávání: '"G C, Todd"'
Publikováno v:
Veterinary and human toxicology. 36(4)
The toxicology of narasin has been extensively investigated in several species of laboratory animals. Acute median lethal po doses varied considerably between species (10 to 40.8 mg/kg). Animals of various species given acutely toxic doses of narasin
Publikováno v:
Teratology. 48(4)
Gemcitabine was given intravenously to female mice on gestation days (GD) 6-15 at doses of 0, 0.05, 0.25, or 1.5 mg/kg/day (0, 0.15, 0.75, or 4.5 mg/m2/day, respectively). Animals assigned to the teratology segment (25/group) were killed on GD 18 for
Publikováno v:
Cancer research. 50(14)
A new pyrimidine antimetabolite, 2',2'-difluorodeoxycytidine, Gemcitabine (LY188011, dFdCyd) has been synthesized and evaluated in experimental tumor models. dFdCyd is a very potent and specific deoxycytidine analogue. The concentration required for
Autor:
Stephens, Amanda L.1, Vifia, Sean M.2
Publikováno v:
Vermont Law Review. Winter2023, Vol. 48 Issue 2, p237-268. 32p.
Publikováno v:
Veterinary Pathology. 16:722-729
Lymphocytic thyroiditis was induced in young Wistar rats by feeding them the immunosuppressive compound frentizole [1-(6-methoxy-2-benzothiazolyl)-3-phenyl urea] for 1 year. About half of the rats given 0.060 and 0.150% frentizole in the diet had lym
Autor:
Baldino, Jacob, McKinny, Scott, Taylor, Jaymes, Wilson, Michael, Buchanan, Briggs, Walker, Robert S., Story, Brett, Bebber, Michelle R., Eren, Metin I.
Publikováno v:
Lithic Technology; Aug2024, Vol. 49 Issue 3, p295-310, 16p
Publikováno v:
Cancer treatment reports. 63(1)
Neurotoxicity is the major side effect occurring during the clinical use of vincristine (VCR). Animal models predictive of potential neurotoxicity would be very useful in the preclinical development of new vinca compounds. To simulate conditions in w
Publikováno v:
Food and cosmetics toxicology. 12(4)
Autor:
Gerald A. Poore, G. C. Todd, R. C. Hoying, R. L. Nelson, George Joseph Cullinan, R. L. Robison, Sweeney Mj, W. E. Jones, W. M. Newlon, Koert Gerzon, C. J. Barnett, R. W. Dyke
Publikováno v:
Journal of medicinal chemistry. 21(1)
Exploration of the effects of "minor" structural differences on the antitumor activity and toxicity of dimeric Catharanthus alkaloids resulted in the preparation of deacetylvinblastine amide (vindesine, VDS) from either vinblastine (VLB) or deacetylv
Publikováno v:
Veterinary pathology. 12(1)